Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Friedrich Felix Hoyer"'
Autor:
Vera B.M. Peters, Friederike Matheis, Immanuel Erdmann, Harshal N. Nemade, David Muders, Martin Toubartz, Merve Torun, Dennis Mehrkens, Simon Geißen, Felix Sebastian Nettersheim, Felix Picard, Henning Guthoff, Alexander Hof, Per Arkenberg, Birgit Arand, Anna Klinke, Volker Rudolph, Hinrich Peter Hansen, Daniel Bachurski, Matti Adam, Friedrich Felix Hoyer, Holger Winkels, Stephan Baldus, Martin Mollenhauer
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionMyocardial infarction (MI) is a significant contributor to morbidity and mortality worldwide. Many individuals who survive the acute event continue to experience heart failure (HF), with inflammatory and healing processes post-MI playing
Externí odkaz:
https://doaj.org/article/57387f045bd6483c8bcab9b7611b4d48
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2022)
The development and clinical approval of immunotherapies has revolutionized cancer therapy. Although the role of adaptive immunity in atherogenesis is now well-established and several immunomodulatory strategies have proven beneficial in preclinical
Externí odkaz:
https://doaj.org/article/bbe628ce48d24160ad7145a885eb9fa5
Autor:
Harshal N Nemade, Dennis Mehrkens, Hannah Sophia Lottermoser, Zeynep Ece Yilmaz, Patrick Schelemei, Felix Ruben Picard, Simon Geißen, Gülsah Fülgen Schwab, Friedrich Felix Hoyer, Henning Guthoff, Alexander Hof, Felix Sebastian Nettersheim, Agapios Sachinidis, Holger Winkels, Stefan Baldus, Manolis Pasparakis, Matti Adam, Martin Mollenhauer
BackgroundReceptor-interacting serine/threonine-protein kinase 1 and 3 (RIPK1 and RIPK3) dependent cell death has been identified as a crucial mediator of abdominal aortic aneurysm (AAA) development. RIPK3 mediates phosphorylation of Mixed lineage ki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e7444009784a01d7997017d30508646
https://doi.org/10.1101/2022.11.24.517638
https://doi.org/10.1101/2022.11.24.517638
Autor:
Julian Jehle, Friedrich Felix Hoyer, Benedikt Schöne, Philipp Pfeifer, Katharina Schild, Imke Jenniches, Laura Bindila, Beat Lutz, Dieter Lütjohann, Andreas Zimmer, Georg Nickenig
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146267 (2016)
BACKGROUND:The endocannabinoid 2-arachidonoylglycerol (2-AG) is a known modulator of inflammation. Despite its high concentration in vascular tissue, the role of 2-AG in atherogenesis has not yet been examined. METHODS:ApoE-deficient mice were sublet
Externí odkaz:
https://doaj.org/article/bd81e1fbe15b4f5397ed63f86dee160c
Autor:
Xinyi Zhang, Cameron S. McAlpine, Yoshiko Iwamoto, Partha Dutta, David Rohde, Maximilian J. Schloss, Sathish Babu Vasamsetti, Friedrich Felix Hoyer, Peter Libby, Emilie Coppin, Filip K. Swirski, Kamila Naxerova, Matthias Nahrendorf, Ganesh Modugu
Publikováno v:
Circulation. 142:244-258
Background: Diabetes mellitus is a prevalent public health problem that affects about one-third of the US population and leads to serious vascular complications with increased risk for coronary artery disease. How bone marrow hematopoiesis contribute
Autor:
Alexander Hof, Simon Geißen, Kezia Singgih, Martin Mollenhauer, Holger Winkels, Thomas Benzing, Stephan Baldus, Friedrich Felix Hoyer
Publikováno v:
Basic research in cardiology. 117(1)
Chronic kidney disease’s prevalence rises globally. Whereas dialysis treatment replaces the kidney’s filtering function and prolongs life, dreaded consequences in remote organs develop inevitably over time. Even milder reductions in kidney functi
Autor:
Kamila Naxerova, Hajera Amatullah, Vanessa Frodermann, Gerard Pasterkamp, I-Hsiu Lee, Fanny Herisson, Nicolas Severe, David Rohde, Gregory R. Wojtkiewicz, Paul M. Ridker, Jana Grune, Friedrich Felix Hoyer, Matthias Nahrendorf, Saskia C. A. de Jager, Yoshiko Iwamoto, Karin Gustafsson, Peter Libby, Lisa Honold, Sebastian Cremer, Gustavo Santos Masson, Ruslan I. Sadreyev, Shuang Zhang, Kate L. Jeffrey, Filip K. Swirski, Gabriel Courties, Fei Ji, Cameron S. McAlpine, Stephen P. Schmidt, Maximilian J. Schloss, Jean G. MacFadyen, Ian D. van Koeverden, David T. Scadden
Publikováno v:
Nature Medicine, 25(11), 1761. Nature Publishing Group
Nature Medicine
Nature Medicine
A sedentary lifestyle, chronic inflammation and leukocytosis increase atherosclerosis; however, it remains unclear whether regular physical activity influences leukocyte production. Here we show that voluntary running decreases hematopoietic activity
Autor:
Peter Libby, Vanessa Frodermann, Friedrich Felix Hoyer, Christoph J. Binder, Christopher T. Chan, Annemijn F. Gregory, Yoshiko Iwamoto, Anne Vassalli, Cameron S. McAlpine, Matthias Nahrendorf, Atsushi Anzai, Filip K. Swirski, Thomas E. Scammell, Shun He, Florian Kahles, Wolfram C. Poller, Ashley M. Fenn, Mehdi Tafti, John E. Mindur, Colin Valet, Sara Rattik, Lennard Halle, M. Kiss
Publikováno v:
Nature
Nature, vol. 566, no. 7744, pp. 383-387
Nature, vol. 566, no. 7744, pp. 383-387
Sleep is integral to life 1 . Although insufficient or disrupted sleep increases the risk of multiple pathological conditions, including cardiovascular disease 2 , we know little about the cellular and molecular mechanisms by which sleep maintains ca
Publikováno v:
Circulation. 139:97-100
Autor:
Filip K. Swirski, Emma D. Klein, David Izquierdo-Garcia, Kenneth Fish, Abraham J. P. Teunissen, Gregory R. Wojtkiewicz, Aaron D. Aguirre, George Soultanidis, Max L. Senders, Esther M. van Leeuwen, Yohana C. Toner, Kiyotake Ishikawa, Yoshiko Iwamoto, Anu E. Meerwaldt, Ken Sakurai, Alexandros Marios Sofias, Matthias Nahrendorf, Carlos Pérez-Medina, Thomas Reiner, Claudia Calcagno, Friedrich Felix Hoyer, Willem J. M. Mulder, Stephen D. Schmidt, Ralph Weissleder, Philip M. Robson, Peter Caravan, Mandy M. T. van Leent, David Rohde
Publikováno v:
Circulation. Cardiovascular Imaging, 13(10):e010586. Lippincott Williams and Wilkins Ltd.
Circulation. Cardiovascular imaging, 13(10):e010586. Lippincott Williams and Wilkins
Circulation. Cardiovascular imaging, 13(10):e010586. Lippincott Williams and Wilkins
Background: Macrophages, innate immune cells that reside in all organs, defend the host against infection and injury. In the heart and vasculature, inflammatory macrophages also enhance tissue damage and propel cardiovascular diseases. Methods: We he