Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Friedrich FO"'
Autor:
Lukas Müller, Daniel Bender, Simon J. Gairing, Friedrich Foerster, Arndt Weinmann, Jens Mittler, Fabian Stoehr, Moritz C. Halfmann, Aline Mähringer-Kunz, Peter R. Galle, Roman Kloeckner, Felix Hahn
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Preliminary work has shown that portal hypertension plays a key role for the prognosis in patients with hepatocellular carcinoma (HCC) undergoing transarterial chemoembolization (TACE). Specifically, the presence of ascites appears to be a s
Externí odkaz:
https://doaj.org/article/b72703a27f5b45bba88bd2d1cdf79e29
Autor:
Najib Ben Khaled, Marie Möller, Leonie S. Jochheim, Catherine Leyh, Ursula Ehmer, Katrin Böttcher, Matthias Pinter, Lorenz Balcar, Bernhard Scheiner, Alexander Weich, Hans Benno Leicht, Valentina Zarka, Liangtao Ye, Julia Schneider, Ignazio Piseddu, Osman Öcal, Monika Rau, Friedrich Sinner, Marino Venerito, Simon Johannes Gairing, Friedrich Förster, Julia Mayerle, Enrico N. De Toni, Andreas Geier, Florian P. Reiter
Publikováno v:
JHEP Reports, Vol 6, Iss 6, Pp 101065- (2024)
Background & Aims: Atezolizumab/bevacizumab (atezo/bev) and lenvatinib have demonstrated efficacy as first-line therapies for hepatocellular carcinoma (HCC). However, vascular endothelial growth factor (VEGF) inhibition with these therapies may be as
Externí odkaz:
https://doaj.org/article/8bfa5b4342fd47ce9b2a38f731714629
Autor:
Dimitrios Vismpas, Friedrich Förster
Publikováno v:
eLife, Vol 13 (2024)
Advanced cryo-EM approaches reveal surprising insights into the molecular structure that allows nascent proteins to be inserted into the membrane of the endoplasmic reticulum.
Externí odkaz:
https://doaj.org/article/03de1a0db44a44c281fd3e6bd286b81c
Autor:
Dirk Graafen, Fabian Stoehr, Moritz C. Halfmann, Tilman Emrich, Friedrich Foerster, Yang Yang, Christoph Düber, Lukas Müller, Roman Kloeckner
Publikováno v:
Cancer Imaging, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background Excellent image quality is crucial for workup of hepatocellular carcinoma (HCC) in patients with liver cirrhosis because a signature tumor signal allows for non-invasive diagnosis without histologic proof. Photon-counting detector
Externí odkaz:
https://doaj.org/article/4b0d13ba3891493ca182a3609543e5aa
Autor:
Marika K. Kucińska, Juliette Fedry, Carmela Galli, Diego Morone, Andrea Raimondi, Tatiana Soldà, Friedrich Förster, Maurizio Molinari
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract The endoplasmic reticulum (ER) is an organelle of nucleated cells that produces proteins, lipids and oligosaccharides. ER volume and activity are increased upon induction of unfolded protein responses (UPR) and are reduced upon activation of
Externí odkaz:
https://doaj.org/article/776f9f177eb6455eaad59ec9b6588efd
Autor:
Lukas Müller, Simon J. Gairing, Friedrich Foerster, Arndt Weinmann, Jens Mittler, Fabian Stoehr, Dirk Graafen, Christoph Düber, Peter R. Galle, Roman Kloeckner, Felix Hahn
Publikováno v:
Cancer Imaging, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background Clinically significant portal hypertension (CSPH) has been identified as an important prognostic factor in patients with hepatocellular carcinoma (HCC) undergoing curative treatment. This study aimed to assess PH estimates as prog
Externí odkaz:
https://doaj.org/article/e549110fd002445bb05d67267d1d67da
Autor:
Lukas Müller, Simon Johannes Gairing, Roman Kloeckner, Friedrich Foerster, Eva Maria Schleicher, Arndt Weinmann, Jens Mittler, Fabian Stoehr, Moritz Christian Halfmann, Christoph Düber, Peter Robert Galle, Felix Hahn
Publikováno v:
Cancer Imaging, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background Early tumor shrinkage (ETS) has been identified as a promising imaging biomarker for patients undergoing immunotherapy for several cancer entities. This study aimed to validate the potential of ETS as an imaging biomarker for pati
Externí odkaz:
https://doaj.org/article/2da7dae9cdaf453d8bcbb823602a367c
Autor:
Marten L. Chaillet, Gijs van der Schot, Ilja Gubins, Sander Roet, Remco C. Veltkamp, Friedrich Förster
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13375 (2023)
Cryo-electron tomography provides 3D images of macromolecules in their cellular context. To detect macromolecules in tomograms, template matching (TM) is often used, which uses 3D models that are often reliable for substantial parts of the macromolec
Externí odkaz:
https://doaj.org/article/1b65b7ae68d847fb896e7403d35af438
Autor:
Florent Waltz, Thalia Salinas-Giegé, Robert Englmeier, Herrade Meichel, Heddy Soufari, Lauriane Kuhn, Stefan Pfeffer, Friedrich Förster, Benjamin D. Engel, Philippe Giegé, Laurence Drouard, Yaser Hashem
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Mitoribosomes are remarkably diverse in their structures and compositions. Here the authors combine biochemistry, genetics, single particle cryo-electron microscopy and in situ cryo-electron tomography to reveal the mitochondrial ribosome of Chlamydo
Externí odkaz:
https://doaj.org/article/413c5709f68a44d2b4550397760ea349
Autor:
Felix Thol, Simon Johannes Gairing, Carolin Czauderna, Thomas Thomaidis, Thomas Gamstätter, Yvonne Huber, Johanna Vollmar, Johanna Lorenz, Maurice Michel, Fabian Bartsch, Lukas Müller, Roman Kloeckner, Peter Robert Galle, Marcus-Alexander Wörns, Jens Uwe Marquardt, Markus Moehler, Arndt Weinmann, Friedrich Foerster
Publikováno v:
JHEP Reports, Vol 4, Iss 3, Pp 100417- (2022)
Background & Aims: Advanced biliary tract cancer (ABTC) is associated with a poor prognosis. Real-world data on the outcome of patients with ABTC undergoing sequential chemotherapies remain scarce, and little is known about treatment options beyond t
Externí odkaz:
https://doaj.org/article/ca54cc67fe5d403f87475984aa7900e7