Zobrazeno 1 - 10
of 2 323
pro vyhledávání: '"Friedrich C, Luft"'
Autor:
Lale A. Ertuglu, Melis Sahinoz, Aseel Alsouqi, Serpil Muge Deger, Andrew Guide, Mindy Pike, Cassianne Robinson‐Cohen, Elvis Akwo, Michael Pridmore, Rachelle Crescenzi, Meena S. Madhur, Annet Kirabo, David G. Harrison, Friedrich C. Luft, Jens Titze, T. Alp Ikizler, Jorge L. Gamboa
Publikováno v:
Physiological Reports, Vol 12, Iss 13, Pp n/a-n/a (2024)
Abstract Background and Aims High tissue sodium accumulation and intermuscular adipose tissue (IMAT) are associated with aging, type 2 diabetes, and chronic kidney disease. In this study, we aim to investigate whether high lower‐extremity tissue so
Externí odkaz:
https://doaj.org/article/2d80718d9ae942958f38c50f8e47b5b3
Autor:
Tong Liu, Inci Dogan, Michael Rothe, Evgenij Potapov, Felix Schoenrath, Maik Gollasch, Friedrich C. Luft, Benjamin Gollasch
Publikováno v:
Lipids in Health and Disease, Vol 22, Iss 1, Pp 1-12 (2023)
Abstract Background Oxylipins, the oxidative metabolites of polyunsaturated fatty acids (PUFAs), serve as key mediators of oxidative stress, inflammatory responses, and vasoactive reactions in vivo. Our previous work has established that hemodialysis
Externí odkaz:
https://doaj.org/article/1a5198b5efcd4d6ab6a17b8a1751251d
Autor:
Yi Li, Niklas Dörmann, Björn Brinschwitz, Melanie Kny, Elisa Martin, Kirsten Bartels, Ning Li, Priyanka Voori Giri, Stefan Schwanz, Michael Boschmann, Susanne Hille, Britta Fielitz, Tobias Wollersheim, Julius Grunow, Stephan B. Felix, Steffen Weber‐Carstens, Friedrich C. Luft, Oliver J. Müller, Jens Fielitz
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 4, Pp 1721-1736 (2023)
Abstract Background Sepsis‐induced intensive care unit‐acquired weakness (ICUAW) features profound muscle atrophy and attenuated muscle regeneration related to malfunctioning satellite cells. Transforming growth factor beta (TGF‐β) is involved
Externí odkaz:
https://doaj.org/article/4f3b327ad2d446c7ae036a28a5240cf3
Autor:
Zhugang Chu, Mario Kassmann, Yoland-Marie Anistan, Friedrich C. Luft, Maik Gollasch, Dmitry Tsvetkov
Publikováno v:
STAR Protocols, Vol 5, Iss 1, Pp 102845- (2024)
Summary: The isolated perfused kidney is a classic ex vivo preparation for studying renal physiology in general and vascular function. Here, we present a protocol for assessing myogenic tone in isolated mouse kidneys as well as vasodilatory and vasoc
Externí odkaz:
https://doaj.org/article/b9e16d014fee4a248769c6b4600eeb28
Autor:
Lukas Zanders, Melanie Kny, Alexander Hahn, Sibylle Schmidt, Sebastian Wundersitz, Mihail Todiras, Ines Lahmann, Arnab Bandyopadhyay, Tobias Wollersheim, Lars Kaderali, Friedrich C. Luft, Carmen Birchmeier, Steffen Weber‐Carstens, Jens Fielitz
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 1, Pp 713-727 (2022)
Abstract Background Sepsis and inflammation can cause intensive care unit‐acquired weakness (ICUAW). Increased interleukin‐6 (IL‐6) plasma levels are a risk factor for ICUAW. IL‐6 signalling involves the glycoprotein 130 (gp130) receptor and
Externí odkaz:
https://doaj.org/article/f560140054434db8868ed4b786ec405c
Autor:
Tobias Opialla, Benjamin Gollasch, Peter H. J. L. Kuich, Lars Klug, Gabriele Rahn, Andreas Busjahn, Simone Spuler, Michael Boschmann, Jennifer A. Kirwan, Friedrich C. Luft, Stefan Kempa
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/571cc22ba1104ade9b7436fd65d709cb
Autor:
Anja Pfau, Karen I. López-Cayuqueo, Nora Scherer, Matthias Wuttke, Annekatrin Wernstedt, Daniela González Fassrainer, Desiree E.C. Smith, Jiddeke M. van de Kamp, Katharina Ziegeler, Kai-Uwe Eckardt, Friedrich C. Luft, Peter S. Aronson, Anna Köttgen, Thomas J. Jentsch, Felix Knauf
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 3 (2023)
Sulfate plays a pivotal role in numerous physiological processes in the human body, including bone and cartilage health. A role of the anion transporter SLC26A1 (Sat1) for sulfate reabsorption in the kidney is supported by the observation of hyposulf
Externí odkaz:
https://doaj.org/article/c70d5d8f3506419b8e69ebb496d32f97
Autor:
Katharina Busch, Melanie Kny, Nora Huang, Tilman E. Klassert, Magdalena Stock, Alexander Hahn, Sebastian Graeger, Mihail Todiras, Sibylle Schmidt, Bishwas Chamling, Michael Willenbrock, Stefan Groß, Doreen Biedenweg, Arnd Heuser, Claus Scheidereit, Christian Butter, Stephan B. Felix, Oliver Otto, Friedrich C. Luft, Hortense Slevogt, Jens Fielitz
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 6, Pp 1653-1668 (2021)
Abstract Background Septic cardiomyopathy worsens the prognosis of critically ill patients. Clinical data suggest that interleukin‐1β (IL‐1β), activated by the NLRP3 inflammasome, compromises cardiac function. Whether or not deleting Nlrp3 woul
Externí odkaz:
https://doaj.org/article/c6eda1ee71e947879615bcafea821786
Autor:
Tobias Opialla, Benjamin Gollasch, Peter H. J. L. Kuich, Lars Klug, Gabriele Rahn, Andreas Busjahn, Simone Spuler, Michael Boschmann, Jennifer A. Kirwan, Friedrich C. Luft, Stefan Kempa
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Background: Assessing detailed metabolism in exercising persons minute-to-minute has not been possible. We developed a “drop-of-blood” platform to fulfill that need. Our study aimed not only to demonstrate the utility of our methodology, but also
Externí odkaz:
https://doaj.org/article/8777a0cad56e41b88752ca154dc2ef44
Autor:
Alexander Hahn, Melanie Kny, Cristina Pablo‐Tortola, Mihail Todiras, Michael Willenbrock, Sibylle Schmidt, Katrin Schmoeckel, Ilka Jorde, Marcel Nowak, Ernst Jarosch, Thomas Sommer, Barbara M. Bröker, Stephan B. Felix, Claus Scheidereit, Steffen Weber‐Carstens, Christian Butter, Friedrich C. Luft, Jens Fielitz
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 11, Iss 1, Pp 103-119 (2020)
Abstract Background Critically ill patients frequently develop muscle atrophy and weakness in the intensive‐care‐unit setting [intensive care unit‐acquired weakness (ICUAW)]. Sepsis, systemic inflammation, and acute‐phase response are major r
Externí odkaz:
https://doaj.org/article/bd0b836c9c4742d59eda00dff324776d