Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Friedrich von Landenberg"'
Autor:
Friedrich Von Landenberg, Hartmut Poth, Michael W. Schmitt, Thomas Goddemeier, Icilio Cavero, Elmar Wimmer
Publikováno v:
European Journal of Pharmacology. 554:46-52
Electrocardiogram (ECG) QT interval prolongation produced by drugs in certain animal models is currently believed to be predictive of cardiac proarrhythmic effects in humans. For this reason, nonclinical assessment of the effects of novel drugs on ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87601c9da8f442162bfa9f12b873cf5b
https://doi.org/10.1016/j.ejphar.2006.09.056
https://doi.org/10.1016/j.ejphar.2006.09.056
Autor:
Friedrich von Landenberg, Wolfgang Völkel, Wolfgang Dekant, Ute M.D. Schauer, Alexander Heusener, Thomas H. Broschard, Thomas Colnot
Publikováno v:
Toxicology and Applied Pharmacology. 216:339-346
The toxicokinetics of 4-MBC after dermal administration were investigated in human subjects and in rats. Humans (3 male and 3 female subjects) were exposed to 4-MBC by topical application of a commercial sunscreen formulation containing 4% 4-MBC (w/w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d244c10b59f368634122a6be694d36ca
https://doi.org/10.1016/j.taap.2006.05.011
https://doi.org/10.1016/j.taap.2006.05.011
Autor:
Friedrich von Landenberg, Barbara Gottschling, Maren Jacobs, Marion Hewicker-Trautwein, Nicole Hübler
Publikováno v:
Toxicology and Applied Pharmacology. 208:266-276
Two tests, a functional observational battery (FOB) and measurement of motor activity, have been used to screen the two NHE inhibitors EMD 96785 and EMD 125021 for neurobehavioral effects. These two NHE inhibitors, which exhibit a marked selectivity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdf78c3841f19280652fb1b7dcb43785
https://doi.org/10.1016/j.taap.2005.02.017
https://doi.org/10.1016/j.taap.2005.02.017
Autor:
Yvon Rabemampianina, Lieve Lammens, Markus Stephan-Gueldner, Friedrich von Landenberg, Claudia Stark, Olympe Depelchin, Rudolf Pfister, David M. Smith, Robert Combes, Ruediger Hack, Joerg Luft, Barry Phillips, Soren Dyring Jacobsen, Susan Sparrow
Publikováno v:
Regulatory Toxicology and Pharmacology. 41:95-101
A working party, comprising two animal welfare organisations and some 12 pharmaceutical companies in Europe, was established to minimise the use of the dog in safety testing. As first step, the participants defined the major objectives of preliminary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ddeeee3a8ebf7ffebe09170b4c03e50
https://doi.org/10.1016/j.yrtph.2004.10.006
https://doi.org/10.1016/j.yrtph.2004.10.006
Autor:
Klaus Krauser, Gerard Descotes, David M. Smith, Yvon Rabemampianina, Friedrich von Landenberg, Soren Dyring Jacobsen, Ruediger Hack, Robert Combes, Barry Phillips, Sue Sparrow, Rudolf Pfister, Joerg Kemkowski, Markus Stephan-Gueldner
Publikováno v:
Alternatives to laboratory animals : ATLA. 32
The primary non-rodent species used in toxicology is the dog. It is generally agreed that, for ethical reasons, dog use should be reduced to the minimum consistent with maintaining the scientific quality of toxicology studies and ensuring human safet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f96221d06b24e56d68d6fe920e9d617
https://pubmed.ncbi.nlm.nih.gov/23581116
https://pubmed.ncbi.nlm.nih.gov/23581116
Autor:
Friedrich von Landenberg, Stephanie Czasch, Katharina Frick, Philip G. Hewitt, Barbara Emde, Tobias Christian Fuchs
Publikováno v:
Toxicologic pathology. 40(7)
Novel urinary protein biomarkers for the detection of acute renal damage, recently accepted by the U.S. Food and Drug Administration, European Medicines Agency, and Pharmaceuticals and Medical Devices Agency (Japan), now have to be validated in pract
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcb4b72305eafa50db9efed136cbbe08
https://pubmed.ncbi.nlm.nih.gov/22581810
https://pubmed.ncbi.nlm.nih.gov/22581810
Autor:
Nicole Huebler, Stefan O. Mueller, Roland Nagel, Franc xois Busquet, Friedrich von Landenberg, Thomas H. Broschard
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 104(1)
The assessment of teratogenic effects of chemicals is generally performed using in vivo teratogenicity assays, for example, in rats or rabbits. We have developed an in vitro teratogenicity assay using the zebrafish Danio rerio embryo combined with an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::944f30463e02d5dc39c82b99da4a841d
https://pubmed.ncbi.nlm.nih.gov/18375544
https://pubmed.ncbi.nlm.nih.gov/18375544
Autor:
Friedrich von Landenberg, Thomas Braunbeck, Stefan Weigt, Francois Busquet, Nicole Huebler, Thomas H. Broschard
Publikováno v:
Toxicology Letters. 180:S96-S97
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9c0927d1371030ab946444ff0bd9296
https://doi.org/10.1016/j.toxlet.2008.06.398
https://doi.org/10.1016/j.toxlet.2008.06.398
Autor:
Lieve Lammens, Peter Stei, Markus Stephan-Gueldner, Rudolf Pfister, Claudia Stark, David M. Smith, Yvon Rabemampianina, Annie Delaunois, Joerg Luft, Friedrich von Landenberg, Ruediger Hack, Barry Phillips, Sue Sparrow, Robert Combes, Anna-Mette Paarup
Publikováno v:
Toxicology. 231:97-98
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9bf2e8d8ca51bdd2263748465ae564f8
https://doi.org/10.1016/j.tox.2006.11.020
https://doi.org/10.1016/j.tox.2006.11.020
Publikováno v:
Toxicology Letters. 189:S143
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aadb891c60bd457dc8da5e7bac062d56
https://doi.org/10.1016/j.toxlet.2009.06.808
https://doi.org/10.1016/j.toxlet.2009.06.808