Development of an in-vitro model for extracorporeal blood pumps to study the effects of artificial pulsatility on human blood

Autor: Barbara Zieger, Denise Schneider, Sam Joé Brixius, Christian Scherer, Armin Buchwald, Georg Trummer, Martin Czerny, Friedhelm Beyersdorf, Hans-Jörg Busch, Christoph Benk, Jan-Steffen Pooth

Publikováno v: Frontiers in Medicine, Vol 10 (2023)

IntroductionThe application of extracorporeal circulation (ECC) systems is known to be associated with several implications regarding hemolysis, inflammation, and coagulation. In the last years, systems with pulsatile blood flow are increasingly used

Externí odkaz: https://doaj.org/article/14c9d0b7df34480ba6b66206a52d0c2d

Serum proteome alterations during conventional and extracorporeal resuscitation in pigs

Autor: Patrick Bernhard, Berit Amelie Bretthauer, Sam Joé Brixius, Hannah Bügener, Johannes Elias Groh, Christian Scherer, Domagoj Damjanovic, Jörg Haberstroh, Georg Trummer, Christoph Benk, Friedhelm Beyersdorf, Oliver Schilling, Jan-Steffen Pooth

Publikováno v: Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-13 (2022)

Abstract Background Only a small number of patients survive an out-of-hospital cardiac arrest (CA) and can be discharged from hospital alive with a large percentage of these patients retaining neurological impairments. In recent years, extracorporeal

Externí odkaz: https://doaj.org/article/4866eeb3d28740908ead88ad88dda34c

Effects of Prolonged Serum Calcium Suppression during Extracorporeal Cardiopulmonary Resuscitation in Pigs

Autor: Jan-Steffen Pooth, Yechi Liu, Ralf Petzold, Christian Scherer, Leo Benning, Maximilian Kreibich, Martin Czerny, Friedhelm Beyersdorf, Christoph Benk, Georg Trummer, Sam Joé Brixius

Publikováno v: Biomedicines, Vol 11, Iss 10, p 2612 (2023)

Controlled reperfusion by monitoring the blood pressure, blood flow, and specific blood parameters during extracorporeal reperfusion after cardiac arrest has the potential to limit ischemia–reperfusion injury. The intracellular calcium overload as

Externí odkaz: https://doaj.org/article/2d86266e59d64fbb942a1de0fc6aa802

Societies of Futures Past: Examining the History and Potential of International Society Collaborations in Addressing the Burden of Rheumatic Heart Disease in the Developing World

Autor: Zachary Obinna Enumah, Percy Boateng, Ralph Morton Bolman, Friedhelm Beyersdorf, Liesl Zühlke, Maurice Musoni, Adriano Tivane, Peter Zilla

Publikováno v: Frontiers in Cardiovascular Medicine, Vol 8 (2021)

This paper explores the role and place of national, regional, and international society collaborations in addressing the major global burden of rheumatic heart disease (RHD). On the same order of HIV, RHD affects over 40 million people worldwide. In

Externí odkaz: https://doaj.org/article/88e6b9a9d0a440b595cf4b5323a26feb

Development and validation of explainable machine learning models for risk of mortality in transcatheter aortic valve implantation: TAVI risk machine scores

Autor: Andreas Leha, Cynthia Huber, Tim Friede, Timm Bauer, Andreas Beckmann, Raffi Bekeredjian, Sabine Bleiziffer, Eva Herrmann, Helge Möllmann, Thomas Walther, Friedhelm Beyersdorf, Christian Hamm, Arnaud Künzi, Stephan Windecker, Stefan Stortecky, Ingo Kutschka, Gerd Hasenfuß, Stephan Ensminger, Christian Frerker, Tim Seidler

Publikováno v: Leha, Andreas; Huber, Cynthia; Friede, Tim; Bauer, Timm; Beckmann, Andreas; Bekeredjian, Raffi; Bleiziffer, Sabine; Herrmann, Eva; Möllmann, Helge; Walther, Thomas; Beyersdorf, Friedhelm; Hamm, Christian; Künzi, Arnaud; Windecker, Stephan; Stortecky, Stefan; Kutschka, Ingo; Hasenfuß, Gerd; Ensminger, Stephan; Frerker, Christian and Seidler, Tim (2023). Development and validation of explainable machine learning models for risk of mortality in transcatheter aortic valve implantation: TAVI risk machine scores. European heart journal. Digital health, 4(3), pp. 225-235. Oxford University Press 10.1093/ehjdh/ztad021

Aims Identification of high-risk patients and individualized decision support based on objective criteria for rapid discharge after transcatheter aortic valve implantation (TAVI) are key requirements in the context of contemporary TAVI treatment. Thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc9aa66b9d6a999583d49c603fc75cd2
https://doi.org/10.1093/ehjdh/ztad021