Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Friederike Steudle"'
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 12 (2020)
GABAA receptors are pentameric GABA-gated chloride channels. The existence of 19 different subunits (six α, three β, three γ, δ, ε, θ, π, and three ρ) in mammalian systems gives rise to an enormous theoretical diversity of GABAA receptor subt
Externí odkaz:
https://doaj.org/article/f4a17d425d514d119e8d59a445c19640
Autor:
Xenia Simeone, David C. B. Siebert, Konstantina Bampali, Zdravko Varagic, Marco Treven, Sabah Rehman, Jakob Pyszkowski, Raphael Holzinger, Friederike Steudle, Petra Scholze, Marko D. Mihovilovic, Michael Schnürch, Margot Ernst
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract γ-Aminobutyric acid type A (GABAA) receptors are pentameric GABA-gated chloride channels that are, in mammalians, drawn from a repertoire of 19 different genes, namely α1-6, β1-3, γ1-3, δ, ε, θ, π and ρ1-3. The existence of this wid
Externí odkaz:
https://doaj.org/article/46343707d7194d3e987086a53ab6033f
Autor:
Petra Scholze, Roshan Puthenkalam, Margot Ernst, Markus Müllegger, Xenia Simeone, Andreas Smetka, Filip Koniuszewski, Friederike Steudle
Publikováno v:
Molecular Pharmacology. 99:39-48
The family of GABAA receptors is an important drug target group in the treatment of sleep disorders, anxiety, epileptic seizures, and many others. The most frequent GABAA receptor subtype is composed of two α-, two β-, and one γ2-subunit, whereas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba009f09b8e9ef3fb9e37c5ff0fe58e0
https://doi.org/10.1124/molpharm.120.000067
https://doi.org/10.1124/molpharm.120.000067
Autor:
Xenia, Simeone, Filip, Koniuszewski, Markus, Müllegger, Andreas, Smetka, Friederike, Steudle, Roshan, Puthenkalam, Margot, Ernst, Petra, Scholze
Publikováno v:
Molecular pharmacology. 99(1)
The family of GABA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fc8744fa769520b72dcf3ea4c2d2a120
https://pubmed.ncbi.nlm.nih.gov/33268553
https://pubmed.ncbi.nlm.nih.gov/33268553
Publikováno v:
eLS. :1-12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb31882a9059ab6b8db7358fc5f589ed
https://doi.org/10.1002/9780470015902.a0000233.pub3
https://doi.org/10.1002/9780470015902.a0000233.pub3
Autor:
Marco Treven, Michael Schnürch, David C. B. Siebert, Petra Scholze, Margot Ernst, Marko D. Mihovilovic, Jure Fabjan, Zdravko Varagic, Laurin Wimmer, Konstantina Bampali, Raphael Holzinger, Friederike Steudle
Publikováno v:
British Journal of Pharmacology. 175:419-428
Background and purpose The GABAA receptors are ligand-gated ion channels, which play an important role in neurotransmission. Their variety of binding sites serves as an appealing target for many clinically relevant drugs. Here, we explored the functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f407f7216807bb6d97c5a9a317bb96a
https://doi.org/10.1111/bph.14087
https://doi.org/10.1111/bph.14087
Autor:
Marco Treven, Margot Ernst, Dina Vasovic, Jure Fabjan, Friederike Steudle, Božidar Brković, Daniel E. Knutson, Aleksandar Obradovic, Branka Divović, James M. Cook, Miroslav M. Savić, Werner Sieghart, Petra Scholze
Publikováno v:
European Journal of Pain
gamma-Aminobutyric acid type A (GABA(A)) receptors containing the alpha 6 subunit are located in trigeminal ganglia, and their reduction by small interfering RNA increases inflammatory temporomandibular and myofascial pain in rats. We thus hypothesiz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fffffdec3b643b9b978f1b4f1fa45521
Autor:
Konstantina Bampali, Friederike Steudle, Marko D. Mihovilovic, Sabah Rehman, Margot Ernst, Zdravko Varagic, Marco Treven, David C. B. Siebert, Raphael Holzinger, Michael Schnürch, Jakob Pyszkowski, Petra Scholze, Xenia Simeone
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
γ-Aminobutyric acid type A (GABAA) receptors are pentameric GABA-gated chloride channels that are, in mammalians, drawn from a repertoire of 19 different genes, namely α1-6, β1-3, γ1-3, δ, ε, θ, π and ρ1-3. The existence of this wide variety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2982ac485839c1cd7c2a388afff92614
http://europepmc.org/articles/PMC5516028
http://europepmc.org/articles/PMC5516028