Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Friederike M Mansfeld"'
Autor:
Pegah Varamini, Friederike M Mansfeld, Joanne T Blanchfield, Bruce D Wyse, Maree T Smith, Istvan Toth
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e41909 (2012)
To enhance the drug-like properties of the endogenous opioid peptide endomorphin-1 (1 = Tyr-Pro-Trp-Phe-NH(2)), the N-terminus of the peptide was modified with 2-aminodecanoic acid, resulting in compound 3. Tyr in compound 1 was replaced with 2,6-dim
Externí odkaz:
https://doaj.org/article/21fea07637ff47759063f511330e0f1d
Autor:
Stephen G. Parker, Ying Yang, Simone Ciampi, Bakul Gupta, Kathleen Kimpton, Friederike M. Mansfeld, Maria Kavallaris, Katharina Gaus, J. Justin Gooding
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Many cell capture systems exist but the characterisation and controlled release of single cells is a challenge. Here, the authors report on the development of a duel trigger release system using a combination of photo and electro triggers to allow fo
Externí odkaz:
https://doaj.org/article/94d7d15e25f5408fa2d9811dcc6d2e3e
Autor:
J. Justin Gooding, Maria Kavallaris, Friederike M. Mansfeld, Ying Yang, Katharina Gaus, Richard D. Tilley
Publikováno v:
Chemical Science
Impedance spectroscopy is a widely used technique for monitoring cell–surface interactions and morphological changes, typically based on averaged signals from thousands of cells. However, acquiring impedance data at the single cell level, can poten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4d6d36f3af5bfa9917d76dfc2a4bbbf
https://doi.org/10.1039/d0sc05489e
https://doi.org/10.1039/d0sc05489e
Autor:
Anand Kumar Meka, Helen Forgham, Joshua A. McCarroll, Yuxue Cao, Roberta Mazzieri, Amirali Popat, Rosa Mistica C. Ignacio, Friederike M. Mansfeld, Maria Kavallaris, Taskeen Iqbal Janjua, Aria Ahmed-Cox
Publikováno v:
Nanoscale. 13(40)
The blood brain barrier (BBB) and blood tumour barrier (BTB) remain a major roadblock for delivering therapies to treat brain cancer. Amongst brain cancers, glioblastoma (GBM) is notoriously difficult to treat due to the challenge of delivering chemo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdd99ebb23540a358e191a4ecbdb2bb6
https://pubmed.ncbi.nlm.nih.gov/34533167
https://pubmed.ncbi.nlm.nih.gov/34533167
Autor:
Aria Ahmed-Cox, Elvis Pandzic, Stuart T. Johnston, Celine Heu, John McGhee, Friederike M. Mansfeld, Edmund J. Crampin, Thomas P. Davis, Renee M. Whan, Maria Kavallaris
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 341
Nanoparticles hold great preclinical promise in cancer therapy but continue to suffer attrition through clinical trials. Advanced, three dimensional (3D) cellular models such as tumor spheroids can recapitulate elements of the tumor environment and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93203767a09b0b4f520332ce3fcb4704
https://pubmed.ncbi.nlm.nih.gov/34915071
https://pubmed.ncbi.nlm.nih.gov/34915071
Autor:
David S. Ziegler, Maria Kavallaris, Tushar Kumeria, Roberta Mazzieri, Amirali Popat, Friederike M. Mansfeld, Aria Ahmed-Cox, Iqira Saeed, Prarthana V. Rewatkar, Ritu Kulshreshtha, Taskeen Iqbal Janjua
Publikováno v:
Advanced drug delivery reviews. 171
Glioblastoma (GBM) is one of the most aggressive cancers of the brain. Despite extensive research over the last several decades, the survival rates for GBM have not improved and prognosis remains poor. To date, only a few therapies are approved for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b704ac2515f87abce9a159f6a8168a22
https://pubmed.ncbi.nlm.nih.gov/33486006
https://pubmed.ncbi.nlm.nih.gov/33486006
Autor:
Sarah M. Y. Ng, Andrew Craig Donohue, Adrian Sulistio, Cindy C. Shu, John F. Quinn, Stephen Lonsdale Birkett, Michael R. Whittaker, Thomas P. Davis, David Valade, Christopher B. Little, Anton Blencowe, Alison M. Bendele, Friederike M. Mansfeld, Asha M. D’Souza, Felisa Reyes-Ortega, Russell John Tait, Greg G. Qiao
The most common treatment for osteoarthritis is daily oral administration of a nonsteroidal anti-inflammatory drug such as diclofenac. This daily dosage regime is often associated with severe side effects. In this study, we explored the potential of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a30b61e9ea86a32c81bda06881c0240
https://hdl.handle.net/11541.2/138572
https://hdl.handle.net/11541.2/138572
Autor:
Anahid Ehteda, Greg M. Arndt, Annafranca Farfalla, Domenico Cassano, Valerio Voliani, Caitlin Ung, Maria Tsoli, Jie Liu, Giuseppe Cirillo, Timothy W. Failes, Dannielle Upton, Salvador Pocoví-Martínez, Maria Kavallaris, David S. Ziegler, Friederike M. Mansfeld, Orazio Vittorio, Christopher J. Katsinas
Publikováno v:
Cancers, Vol 13, Iss 1278, p 1278 (2021)
Cancers
Volume 13
Issue 6
Cancers
Volume 13
Issue 6
Simple Summary Diffuse intrinsic pontine gliomas (DIPGs) are the most aggressive high-grade gliomas known to affect children. Due to the infiltrative nature of the DIPG tumours in the brainstem, they are very difficult to treat. Unfortunately, childr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::882e859f2b7b556b8f06aecf0293aa4c
https://doi.org/10.3390/cancers13061278
https://doi.org/10.3390/cancers13061278
Autor:
David Chang, May Lim, Jeroen A. C. M. Goos, Ruirui Qiao, Yun Yee Ng, Friederike M. Mansfeld, Michael Jackson, Thomas P. Davis, Maria Kavallaris
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 9 (2018)
Frontiers in Pharmacology, Vol 9 (2018)
Hyperthermia, the mild elevation of temperature to 40–43°C, can induce cancer cell death and enhance the effects of radiotherapy and chemotherapy. However, achievement of its full potential as a clinically relevant treatment modality has been rest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3bb373f071da93f24b23b138ff73703
http://wrap.warwick.ac.uk/107903/1/WRAP-biologically-targeted-magnetic-hyperthermia-potential-Davis-2018.pdf
http://wrap.warwick.ac.uk/107903/1/WRAP-biologically-targeted-magnetic-hyperthermia-potential-Davis-2018.pdf
Autor:
J. Justin Gooding, Kathleen Kimpton, Bakul Gupta, Maria Kavallaris, Friederike M. Mansfeld, Simone Ciampi, Stephen G. Parker, Ying Yang, Katharina Gaus
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Nature Communications
Nature Communications
For many normal and aberrant cell behaviours, it is important to understand the origin of cellular heterogeneity. Although powerful methods for studying cell heterogeneity have emerged, they are more suitable for common rather than rare cells. Explor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::664d5ce17a4babaaf59c1d3eeb87ab27
https://doi.org/10.1038/s41467-018-04701-y
https://doi.org/10.1038/s41467-018-04701-y