Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Friederike L. Jayes"'
Autor:
Md Soriful Islam, Sadia Afrin, Bhuchitra Singh, Friederike L. Jayes, Joshua T. Brennan, Mostafa A. Borahay, Phyllis C. Leppert, James H. Segars
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 7, Pp n/a-n/a (2021)
Abstract Background Uterine fibroids are highly prevalent, collagen‐rich, mechanically stiff, fibrotic tumors for which new therapeutic options are needed. Increased extracellular matrix (ECM) stiffness activates mechanical signaling and Hippo/YAP
Externí odkaz:
https://doaj.org/article/ec5c65d77a9d4bec9bd60d4bb10a2bae
Publikováno v:
Journal of Functional Biomaterials, Vol 2, Iss 3, Pp 173-194 (2011)
Temperature-triggered copolymers are proposed for a number of bio-applications but there is no ideal material platform, especially for injectable drug delivery. Options are needed for degradable biomaterials that not only respond to temperature but a
Externí odkaz:
https://doaj.org/article/6203c25efd864ffe9cf0e34a11b4ef75
Publikováno v:
Obstetrics and Gynecology International, Vol 2014 (2014)
The role of the extracellular matrix (ECM) and mechanotransduction as an important signaling factor in the human uterus is just beginning to be appreciated. The ECM is not only the substance that surrounds cells, but ECM stiffness will either compres
Externí odkaz:
https://doaj.org/article/ffa5b8691d8c4ef6ba57d5fe158ff41b
Autor:
Ayman Al-Hendy, Andrea Tinelli, Quaker E. Harmon, James H. Segars, Emmanuel Paul, Elizabeth A. Stewart, Serdar E. Bulun, William H. Catherino, Daniel J. Tschumperlin, Phyllis C. Leppert, José A. Teixeira, Merrick T. Ducharme, Aymara Mas Perucho, Carlos Simón, Ami R. Zota, Darlene Dixon, Friederike L. Jayes, Donna D. Baird
Publikováno v:
F S Sci
Scientists from multiple basic disciplines and an international group of physician-scientists from the field of obstetrics and gynecology presented recent studies and discussed new and evolving theories of uterine fibroid etiology, growth and develop
Autor:
Soriful Islam, James H. Segars, Joshua T. Brennan, Sadia Afrin, Mostafa A. Borahay, Friederike L. Jayes, Phyllis C. Leppert, Bhuchitra Singh
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 7, Pp n/a-n/a (2021)
Clinical and Translational Medicine
Clinical and Translational Medicine
Background Uterine fibroids are highly prevalent, collagen‐rich, mechanically stiff, fibrotic tumors for which new therapeutic options are needed. Increased extracellular matrix (ECM) stiffness activates mechanical signaling and Hippo/YAP promoting
Autor:
Robert B. Vachieri, Saad A. Khan, Friederike L. Jayes, John M. Cullen, Darlene K. Taylor, Ria D. Corder, Sashi V. Gadi
Publikováno v:
Acta Biomater
Uterine fibroids are stiff, benign tumors containing excessive, disordered collagens that occur in 70-80% of women before age 50 and cause bleeding and pain. Collagenase Clostridium histolyticum (CCH) is a bacterial enzyme capable of digesting the co
Autor:
Nazema Y. Siddiqui, Ken Gall, Andrew Miller, Friederike L. Jayes, Stanley J. Robboy, Frank C. Marini, Jennifer A. Bickhaus, Alison C. Weidner, Matthew O. Fraser, Cindy L. Amundsen
Publikováno v:
Female pelvic medicinereconstructive surgery. 27(2)
OBJECTIVE Polycarbonate urethane (PCU) is a new biomaterial, and its mechanical properties can be tailored to match that of vaginal tissue. We aimed to determine whether vaginal host immune and extracellular matrix responses differ after PCU versus l
Autor:
Stanley J. Robboy, Friederike L. Jayes, Alison C. Weidner, Jennifer A. Bickhaus, Ken Gall, Cindy L. Amundsen, Matthew O. Fraser, Nazema Y. Siddiqui, Frank C. Marini
Publikováno v:
Female pelvic medicinereconstructive surgery. 27(2)
OBJECTIVES We sought to determine whether vaginal host immune cellular and extracellular matrix responses are altered in a rat sacrocolpopexy model when lightweight polypropylene mesh is attached on tension versus without tension. METHODS We performe
Autor:
Phyllis C. Leppert, David W. Schomberg, Liping Feng, Friederike L. Jayes, Lauren N.C. Johnson
Publikováno v:
Current Protein & Peptide Science. 18:155-166
Utilizing both primary myometrial cells and a myometrial cell line, we show here that myometrial cells undergo transition to a myofibroblast-like phenotype after a biological insult of 72 hours serum starvation and serum add-back (SB: 1% to 10% FBS).
Autor:
James H. Segars, Joshua T. Brennan, Friederike L. Jayes, Soriful Islam, Phyllis C. Leppert, Bhuchitra Singh
Publikováno v:
Fertility and Sterility. 114:e86