Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Friederike Herbst"'
Autor:
Tim Schmäche, Juliane Fohgrub, Anna Klimova, Karin Laaber, Stephan Drukewitz, Felix Merboth, Alexander Hennig, Therese Seidlitz, Friederike Herbst, Franziska Baenke, Anne-Marlen Ada, Thomas Groß, Carina Wenzel, Claudia R. Ball, Christian Praetorius, Thomas Schmidt, Barbara Ringelband-Schilling, Ronald Koschny, Albrecht Stenzinger, Ingo Roeder, Dirk Jaeger, Sebastian Zeissig, Thilo Welsch, Daniela Aust, Hanno Glimm, Gunnar Folprecht, Jürgen Weitz, Georg M. Haag, Daniel E. Stange
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-8 (2024)
Abstract Background and aims This study sought to determine the value of patient-derived organoids (PDOs) from esophago-gastric adenocarcinoma (EGC) for response prediction to neoadjuvant chemotherapy (neoCTx). Methods Endoscopic biopsies of patients
Externí odkaz:
https://doaj.org/article/ef3c4b197b1249f6b014c0fc293e9167
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-13 (2022)
Abstract Chimeric Antigen Receptor (CAR) T-cells represent a breakthrough in personalized cancer therapy. In this strategy, synthetic receptors comprised of antigen recognition, signaling, and costimulatory domains are used to reprogram T-cells to ta
Externí odkaz:
https://doaj.org/article/56e54c566c9b454fa23542e0f2dcf4c5
Autor:
Sarah Weber, Sebastian E. Koschade, Christopher M. Hoffmann, Taronish D. Dubash, Klara M. Giessler, Sebastian M. Dieter, Friederike Herbst, Hanno Glimm, Claudia R. Ball
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-12 (2019)
Abstract Background While colorectal cancer (CRC) patients with localized disease have a favorable prognosis, the five-year-survival rate in patients with distant spread is still below 15%. Hence, a detailed understanding of the mechanisms regulating
Externí odkaz:
https://doaj.org/article/ba1aaeb46e174969b3e687ece0a945c4
Autor:
Claudia R Ball, Felix Oppel, Karl Roland Ehrenberg, Taronish D Dubash, Sebastian M Dieter, Christopher M Hoffmann, Ulrich Abel, Friederike Herbst, Moritz Koch, Jens Werner, Frank Bergmann, Naveed Ishaque, Manfred Schmidt, Christof von Kalle, Claudia Scholl, Stefan Fröhling, Benedikt Brors, Wilko Weichert, Jürgen Weitz, Hanno Glimm
Publikováno v:
EMBO Molecular Medicine, Vol 9, Iss 7, Pp 918-932 (2017)
Abstract Although tumor‐initiating cell (TIC) self‐renewal has been postulated to be essential in progression and metastasis formation of human pancreatic adenocarcinoma (PDAC), clonal dynamics of TICs within PDAC tumors are yet unknown. Here, we
Externí odkaz:
https://doaj.org/article/806e5c3796d448e3a3f8956eba08fa15
Autor:
Karl Roland Ehrenberg, Jianpeng Gao, Felix Oppel, Stephanie Frank, Na Kang, Tim Kindinger, Sebastian M. Dieter, Friederike Herbst, Lino Möhrmann, Taronish D. Dubash, Erik R. Schulz, Hendrik Strakerjahn, Klara M. Giessler, Sarah Weber, Ava Oberlack, Eva-Maria Rief, Oliver Strobel, Frank Bergmann, Felix Lasitschka, Jürgen Weitz, Hanno Glimm, Claudia R. Ball
Publikováno v:
Cells, Vol 8, Iss 2, p 142 (2019)
In highly aggressive malignancies like pancreatic cancer (PC), patient-derived tumor models can serve as disease-relevant models to understand disease-related biology as well as to guide clinical decision-making. In this study, we describe a two-step
Externí odkaz:
https://doaj.org/article/1256f87644bb43a386fa5d4e662c089e
Autor:
Anna Rommer, Birgit Steinmetz, Friederike Herbst, Hubert Hackl, Petra Heffeter, Daniela Heilos, Martin Filipits, Katarina Steinleitner, Shayda Hemmati, Irene Herbacek, Ilse Schwarzinger, Katharina Hartl, Pieter Rondou, Hanno Glimm, Kadin Karakaya, Alwin Krämer, Walter Berger, Rotraud Wieser
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56308 (2013)
Overexpression of ecotropic viral integration site 1 (EVI1) is associated with aggressive disease in acute myeloid leukemia (AML). Despite of its clinical importance, little is known about the mechanism through which EVI1 confers resistance to antile
Externí odkaz:
https://doaj.org/article/585c0852f1d94e859d4e2ecfd8b60976
Autor:
Daniela Richter, G. Folprecht, Christoph Heining, Karin Laaber, Heiner Nebelung, Sebastian Uhrig, Daniela Aust, Stefan Frohling, Barbara Hutter, Arne Jahn, Hanno Glimm, Friederike Herbst, Dorothea Hanf
Publikováno v:
JCO Precision Oncology. :687-694
Autor:
Friederike Herbst, Spyridon Tsikalakis, Janina Müller, Vasilis G. Gregoriou, Stella Arelaki, Maria Goulielmaki, Alkmini D. Nega, Claudia R. Ball, Stefan Wiemann, Antonia Dimitrakopoulou-Strauss, Christos L. Chochos, Panagiota Koralli
Publikováno v:
Materials Chemistry Frontiers. 5:4950-4962
Conjugated polymer nanoparticles (CPNs) have emerged as a new promising class of cancer theranostic agents due to their desirable optical features, such as high absorption coefficient and photoluminescence quantum yields, spanning from the ultraviole
Autor:
Ava Oberlack, Mathias Kalxdorf, Katharina Jechow, Mark Kriegsmann, Stephan M Tirier, Jeroen Krijgsveld, Christian Conrad, Roland Eils, Karin Laaber, Torsten Müller, Teresa G Krieger, Martin Schneider, Friederike Herbst, Mario Huerta, Sebastian M. Dieter, Claudia R. Ball, Robert Lorenz Chua, Foo Wei Ten, Martina K. Zowada, Katharina Kriegsmann, Jeongbin Park, Hanno Glimm
Publikováno v:
Cancers, Vol 13, Iss 1097, p 1097 (2021)
Cancers
Volume 13
Issue 5
Cancers
Volume 13
Issue 5
Simple Summary Different types of cells with tumor-initiating cell (TIC) activity contribute to colorectal cancer (CRC) progression and resistance to anti-cancer treatment. In this study, we aimed to understand whether different cell types exist with
Autor:
Martin Lange, Erik Schulz, Mario Huerta, Mona Blatter, Ali Nowrouzi, Bernhard Kuster, Ulrike Uhrig, Karin Laaber, Axel Benner, Hanno Glimm, Claudia R. Ball, Sina Kreth, Dominik Mumberg, Kerstin Putzker, Friederike Herbst, Joerg Weiske, Hannes Hahne, Sarah Johannes, Gerhard Siemeister, Frank Westermann, Andrea Haegebarth, Martina K. Zowada, Gabriele Stoehr, Simon Holton, Paula L Codo, Joe Lewis, Sebastian M. Dieter, Ulrike Scheib, Lena-Marit Toepper, Sylvia Martin, Christine Siegl, Anna L. Ostermann-Parucha
Summary Novel treatment options for metastatic colorectal cancer (CRC) are urgently needed to improve patient outcome. Here, we screen a library of non-characterized small molecules against a heterogeneous collection of patient-derived CRC spheroids.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a410f992a87b35fec1505c6f97a79632
https://mediatum.ub.tum.de/doc/1652086/document.pdf
https://mediatum.ub.tum.de/doc/1652086/document.pdf