Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Friederike Berberich-Siebelt"'
Autor:
Chunguang Liang, Silvia Spoerl, Yin Xiao, Katharina M. Habenicht, Sigrun S. Haeusl, Isabel Sandner, Julia Winkler, Nicholas Strieder, Rüdiger Eder, Hanna Stanewsky, Christoph Alexiou, Diana Dudziak, Andreas Rosenwald, Matthias Edinger, Michael Rehli, Petra Hoffmann, Thomas H. Winkler, Friederike Berberich-Siebelt
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-16 (2024)
Abstract In clinical situations, peripheral blood accessible CD3+CD4+CXCR5+ T-follicular helper (TFH) cells may have to serve as a surrogate indicator for dysregulated germinal center responses in tissues. To determine the heterogeneity of TFH cells
Externí odkaz:
https://doaj.org/article/7c0d3bc23f4c4d5f842af48b76085e66
Autor:
Sigrid Bülow, Katharina U. Ederer, Jonas M. Holzinger, Lisa Zeller, Maren Werner, Martina Toelge, Christina Pfab, Sarah Hirsch, Franziska Göpferich, Andreas Hiergeist, Friederike Berberich-Siebelt, André Gessner
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113929- (2024)
Summary: Neutrophil-derived bactericidal/permeability-increasing protein (BPI) is known for its bactericidal activity against gram-negative bacteria and neutralization of lipopolysaccharide. Here, we define BPI as a potent activator of murine dendrit
Externí odkaz:
https://doaj.org/article/fded7e7fc781498cb3a38118486a84c8
Autor:
M Zeeshan Chaudhry, Lisa Borkner, Upasana Kulkarni, Friederike Berberich-Siebelt, Luka Cicin-Sain
Publikováno v:
PLoS Pathogens, Vol 20, Iss 2, p e1012025 (2024)
Cytomegalovirus (CMV) induces a unique T cell response, where antigen-specific populations do not contract, but rather inflate during viral latency. It has been proposed that subclinical episodes of virus reactivation feed the inflation of CMV-specif
Externí odkaz:
https://doaj.org/article/0eb04c2d77ee4f83a07608ad30411962
Autor:
Rishav Seal, Lara S. U. Schwab, Cristina M. Chiarolla, Nadine Hundhausen, Georg Heinrich Klose, Simone Reu-Hofer, Andreas Rosenwald, Johannes Wiest, Friederike Berberich-Siebelt
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
In inflammatory bowel disease, dysregulated T cells express pro-inflammatory cytokines. Using a chronic azoxymethane (AOM)/dextran sulfate sodium (DSS)-induced colitis model resembling ulcerative colitis, we evaluated whether and when treatment with
Externí odkaz:
https://doaj.org/article/d73909a7d100442684c5123cadf784a8
Autor:
Martina Seefried, Nadine Hundhausen, Irena Kroeger, Maike Büttner-Herold, Petra Hoffmann, Matthias Edinger, Evelyn Ullrich, Friederike Berberich-Siebelt, William J. Britt, Michael Mach, Thomas H. Winkler
Publikováno v:
JCI Insight, Vol 8, Iss 5 (2023)
Reactivation of human cytomegalovirus (HCMV) from latency is a frequent complication following hematopoietic stem cell transplantation (HSCT). The development of acute graft-versus-host disease (GVHD) is a significant risk factor for HCMV disease. Us
Externí odkaz:
https://doaj.org/article/85e5e8164bca4a6aa5ac4dbeda5eced2
Autor:
Sabrina Giampaolo, Cristina M. Chiarolla, Konrad Knöpper, Martin Vaeth, Matthias Klein, Azeem Muhammad, Tobias Bopp, Friederike Berberich-Siebelt, Amiya K. Patra, Edgar Serfling, Stefan Klein-Hessling
Publikováno v:
iScience, Vol 26, Iss 3, Pp 106234- (2023)
Summary: In thymus, the ablation of T cell receptor (TCR)-activated transcription factor NFATc1 or its inducible isoforms during the double-negative (DN) stages of thymocyte development leads to a marked increase in γδ thymocytes whereas the develo
Externí odkaz:
https://doaj.org/article/674aa6d2228e4a759cbeb67b1400a61e
Autor:
Anika Koenig, Martin Vaeth, Yin Xiao, Cristina M. Chiarolla, Raghu Erapaneedi, Matthias Klein, Lena Dietz, Nadine Hundhausen, Snigdha Majumder, Felix Schuessler, Tobias Bopp, Stefan Klein-Hessling, Andreas Rosenwald, Ingolf Berberich, Friederike Berberich-Siebelt
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
CD4+CXCR5+Foxp3+ T-follicular regulatory (TFR) cells control the germinal center responses. Like T-follicular helper cells, they express high levels of Nuclear Factor of Activated T-cells c1, predominantly its short isoform NFATc1/αA. Ablation of NF
Externí odkaz:
https://doaj.org/article/2abac50c221949b989cc5a8fa7379943
Autor:
Franziska Karl, Michael Hudecek, Friederike Berberich-Siebelt, Andreas Mackensen, Dimitrios Mougiakakos
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Allogeneic-hematopoietic stem cell transplantation (allo-HSCT) represents the only curative treatment option for numerous hematological malignancies. Elimination of malignant cells depends on the T-cells’ Graft-versus-Tumor (GvT) effect. However, G
Externí odkaz:
https://doaj.org/article/987643ba580341958788e6c05f200cc5
Autor:
Snigdha Majumder, Isabelle Jugovic, Domenica Saul, Luisa Bell, Nadine Hundhausen, Rishav Seal, Andreas Beilhack, Andreas Rosenwald, Dimitrios Mougiakakos, Friederike Berberich-Siebelt
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Gene editing of primary T cells is a difficult task. However, it is important for research and especially for clinical T-cell transfers. CRISPR/Cas9 is the most powerful gene-editing technique. It has to be applied to cells by either retroviral trans
Externí odkaz:
https://doaj.org/article/ba4a939100cb4bc385aea5698087a5bc
Autor:
Luisa Bell, Alexander Lenhart, Andreas Rosenwald, Camelia M. Monoranu, Friederike Berberich-Siebelt
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
In gray matter pathology of multiple sclerosis, neurodegeneration associates with a high degree of meningeal inflammatory activity. Importantly, ectopic lymphoid follicles (eLFs) were identified at the inflamed meninges of patients with progressive m
Externí odkaz:
https://doaj.org/article/a04cbd4f376042f9984b9bc417ef9daa