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of 7
pro vyhledávání: '"Friederike Bathe"'
Autor:
Manfred Schliwa, Lucia Driller, Friederike Bathe, Guenther Woehlke, Renate Dombi, Katrin Hahlen
Publikováno v:
Molecular Biology of the Cell. 16:3529-3537
Kinesin-1 dimerizes via the coiled-coil neck domain. In contrast to animal kinesins, neck dimerization of the fungal kinesin-1 NcKin requires additional residues from the hinge. Using chimeric constructs containing or lacking fungal-specific elements
Cyclin-dependent protein kinases (CDKs) are usually involved in cell cycle regulation. However, Cdk9 is an exception and promotes RNA synthesis through phosphorylation of the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f21dd9b7c6a9d2aff1c81b80a7c94b5a
https://europepmc.org/articles/PMC3535853/
https://europepmc.org/articles/PMC3535853/
Autor:
Elke Wohlmann, Sabrina Hettinger, Reinhard Fischer, Claudia Kempf, Aysha H. Osmani, Friederike Bathe, Stephen A. Osmani
Publikováno v:
Eukaryotic cell. 9(12)
Cdk9-like kinases in complex with T-type cyclins are essential components of the eukaryotic transcription elongation machinery. The full spectrum of Cdk9/cyclin T targets, as well as the specific consequences of phosphorylations, is still largely und
Publikováno v:
Journal of muscle research and cell motility. 27(2)
Kinesin-1 microtubule motors are common kinesin motors from protozoa, fungi and animals. They transport vesicular or particle cargo in a strictly regulated manner. The relatively well-studied tail inhibition mechanism is based on a conformational cha
Publikováno v:
GBM Annual Spring meeting Mosbach 2005. 2005
Publikováno v:
Journal of Muscle Research & Cell Motility; Feb2006, Vol. 27 Issue 2, p153-160, 8p
Publikováno v:
Biophysical Journal. (4):1407-1412
Kinesin-1 is a dimeric motor protein that moves stepwise along microtubules. A two-stranded α-helical coiled-coil formed by the neck domain links the two heads of the molecule, and forces the motor heads to alternate. By exchanging the particularly