Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Frieder Kroener"'
Autor:
Fabian Bickel, François Griaud, Wolfram Kern, Frieder Kroener, Manuela Gritsch, Jérôme Dayer, Samuel Barteau, Blandine Denefeld, Chi-Ya Kao-Scharf, Manuel Lang, Izabela Slupska-Muanza, Carla Schmidt, Matthias Berg, Jürgen Sigg, Lina Boado, Dirk Chelius
Publikováno v:
mAbs, Vol 15, Iss 1 (2023)
ABSTRACTIn this study, we report the isomerization of an aspartic acid residue in the complementarity-determining region (CDR) of crizanlizumab as a major degradation pathway. The succinimide intermediate and iso-aspartic acid degradation products we
Externí odkaz:
https://doaj.org/article/704ad1576cf945d7aab734d00191b085
Autor:
Fabian Bickel, François Griaud, Wolfram Kern, Frieder Kroener, Manuela Gritsch, Jérôme Dayer, Samuel Barteau, Blandine Denefeld, Chi-Ya Kao-Scharf, Manuel Lang, Izabela Slupska-Muanza, Carla Schmidt, Matthias Berg, Jürgen Sigg, Lina Boado, Dirk Chelius
Publikováno v:
mAbs. 15(1)
In this study, we report the isomerization of an aspartic acid residue in the complementarity-determining region (CDR) of crizanlizumab as a major degradation pathway. The succinimide intermediate and iso-aspartic acid degradation products were succe
Autor:
Bickel, Fabian, Griaud, François, Kern, Wolfram, Kroener, Frieder, Gritsch, Manuela, Dayer, Jérôme, Barteau, Samuel, Denefeld, Blandine, Kao-Scharf, Chi-Ya, Lang, Manuel, Slupska-Muanza, Izabela, Schmidt, Carla, Berg, Matthias, Sigg, Jürgen, Boado, Lina, Chelius, Dirk
Publikováno v:
mAbs; Jan-Dec2023, Vol. 15 Issue 1, p1-12, 12p