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pro vyhledávání: '"Friedemann J. Schaub"'
Autor:
Friedemann J. Schaub, Kirsten Sayson, Nicola Ferri, Ronald A. Seifert, W. Conrad Liles, Daniel F. Bowen-Pope
Publikováno v:
Circulation Research. 93:515-522
We previously reported that treatment of human vascular smooth muscle cells (SMCs) with proapoptotic stimuli, including Fas ligand plus cycloheximide (FasL/Chx), or overexpression of Fas-associated death domain protein (FADD) result in increased expr
Publikováno v:
Trends in cardiovascular medicine. 11(1)
Unlike necrosis, apoptosis is classically considered to be “silent,” (i.e., self-contained and non-inflammatory). In this review, we describe the system that we developed to regulate apoptosis of smooth muscle cells (SMC) in vivo. We have used th
Autor:
R K Ramachandran, L D Adams, W C Liles, Ronald A. Seifert, David K. Han, Stephen M. Schwartz, Friedemann J. Schaub, Daniel F. Bowen-Pope, Scott A. Coats
Publikováno v:
Nature medicine. 6(7)
Apoptosis of smooth muscle cells is a common feature of vascular lesions but its pathophysiological significance is not known. We demonstrate that signals initiated by regulated Fas-associated death domain protein overexpression in rat vascular smoot