Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Fridrika Hardardottir"'
Publikováno v:
The Journal of Experimental Medicine
Experimental autoimmune encephalomyelitis (EAE) is an animal model for autoimmune central nervous system disease mediated by CD4 T cells. To examine the role of B cells in the induction of EAE, we used B10.PL (I-Au) mice rendered deficient in B cells
Publikováno v:
Proceedings of the National Academy of Sciences. 92:354-358
Although the clonal selection theory states that lymphocytes should bear only a single specificity of receptor, there is much evidence that some T cells, at least, bear two receptors. Here, we have used mice transgenic for genes encoding an autoreact
Autor:
Jody L. Baron, Harald G. Foellmer, Fridrika Hardardottir, Iqbal S. Grewal, Charles A. Janeway, Richard A. Flavell, Kate D. Grewal, Jianchao Xu
Publikováno v:
Science (New York, N.Y.). 273(5283)
The mechanism of CD40 ligand (CD40L)-mediated in vivo activation of CD4(+) T cells was examined by investigation of the development of experimental allergic encephalomyelitis (EAE) in CD40L-deficient mice that carried a transgenic T cell receptor spe
Publikováno v:
Molecular immunology. 30(6)
Somatic mutations and cell lineage relationships were examined in a large panel of hybridomas derived from a single mouse 21 days after a primary immunization with NP-CGG. Among 21 λ-bearing anti-NP hybridomas 18 distinct cell lineages were observed