Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Frida Gustafsson"'
Autor:
Elias Bengtsson, Frida Gustafsson
Publikováno v:
European Financial Management. 29(1):150-195
This article investigates if cryptocurrencies returns' are similarly affected by a selection of demand- and supply-side determinants. Homogeneity among cryptocurrencies is tested via a least absolute shrinkage and selection operator (LASSO) model whe
Autor:
Mark J. Anderton, Jasper Komen, Jayati Basak, Frida Gustafsson, Andy Mead, Joanna Harding, Emilyanne Leonard
Publikováno v:
Toxicology Letters. 280:S264-S265
Autor:
Elizabeth Underwood, Paul Hemsley, Jonathan P. Orme, Andrew X. Zhang, Frida Gustafsson, Anna Cronin, Jeffrey W. Johannes, Lucy Riches, Jenni Nikkilä, Fiona Pachl, Ruth Macdonald, Sinbad Sweeney, Elisabetta Leo, Mark J. O'Connor, Verity Talbot, Giuditta Illuzzi, Andrew N. Mead, Michal Bista, Piero Ricchiuto, Eric Miele, Andrew Pike, Debora A. Roaquin, Ana J. Narvaez, Glen Hawthorne
Publikováno v:
Cancer Research. 78:LB-273
Four poly(ADP-ribose) polymerase (PARP) inhibitors have now presented phase 3 monotherapy data showing compelling benefit of targeting tumours enriched with DNA damage response (DDR) pathway deficiencies, including BRCA gene mutations. Indirect treat
Autor:
Frida Gustafsson, Philip A. MacFaul, Simon Brocklehurst, Kevin Hickling, James Goodman, Ryan A. Bragg, Steve Swallow, Jonathan Tugwood
Publikováno v:
Chemical research in toxicology. 28(10)
The oral dipeptidyl peptidase 1 (DPP1) inhibitor AZD5248 showed aortic binding in a rat quantitative whole-body autoradiography (QWBA) study, and its development was terminated prior to human dosing. A mechanistic hypothesis for this finding was esta
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 137(1)
Drug toxicity to T-antigen-immortalized human liver epithelial (THLE) cells stably transfected with plasmid vectors that encoded human cytochrome P450s 1A2, 2C9, 2C19, 2D6, or 3A4, or an empty plasmid vector (THLE-Null), was investigated. An automate
Autor:
Timothy Schulz-Utermoehl, J. Gerry Kenna, Julie Eakins, Simone H. Stahl, Ian D. Wilson, Scott W. Martin, Alison V. M. Rodrigues, Frida Gustafsson, Helen Rollison, Sunil Sarda
Publikováno v:
Archives of toxicology. 87(8)
The carboxylic acid NSAID fenclozic acid exhibited an excellent preclinical safety profile and promising clinical efficacy, yet was withdrawn from clinical development in 1971 due to hepatotoxicity observed in clinical trials. A variety of modern in
Autor:
Emre M. Isin, David G. Temesi, J. Gerry Kenna, Johanna Midlöv, Alison J. Foster, Neal Castagnoli, Lucy H. Prime, Frida Gustafsson
Publikováno v:
Chemical research in toxicology. 26(1)
The cannabinoid type 1 receptor (CB1r) antagonist rimonabant was approved in 2006 for the treatment of obesity but was withdrawn in 2008 due to serious drug-related psychiatric disorders. In vitro metabolism studies with rimonabant have revealed high
Autor:
Martin R. Brown, Edward K. Ainscow, Frida Gustafsson, Jean Pierre Valentin, Tony Goodall, James Pilling, Joanne Bowes, Paul J. Ciaccio
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 64:e12
Autor:
Ryan A. Bragg, Simon Brocklehurst, Frida Gustafsson, James Goodman, Kevin Hickling, Philip A. MacFaul, Steve Swallow, Jonathan Tugwood
Publikováno v:
Chemical Research in Toxicology; Oct2015, Vol. 28 Issue 10, p1991-1999, 9p