Pyrimidin‐6‐yl trifluoroborate salts as versatile templates for heterocycle synthesis

Autor: Cousins, D.L., Fricero, P., Kopf, K.P.M., McColl, E.J., Czechtizky, W., Lim, Y.H., Harrity, J.P.A.

We report a novel and general method to access a highly under‐studied privileged scaffold – pyrimidines bearing a trifluoroborate at C4, and highlight the broad utility of these intermediates in a rich array of downstream functionalization reacti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::9496c942b5e62bdda28ca9604027ec84
https://eprints.whiterose.ac.uk/171513/7/anie.202101297.pdf

DIGITALIZAREA DREPTULUI ŞI A ADMINISTRAȚIEI PUBLICE ÎN CONTEXTUL PANDEMIEI. DIGITALIZAREA PROCEDURILOR CIVILE ŞI A CĂILOR DE EXECUTARE. (Romanian)

Autor: Fricero, Natalie

Publikováno v: Romanian Journal of Compulsory Execution / Revista Română de Executare Silită; 2021, Vol. 17 Issue 1, p11-14, 4p

Pyrimidin-6-yl Trifluoroborate Salts as Versatile Templates for Heterocycle Synthesis.

Autor: Cousins DL; Department of Chemistry, University of Sheffield, Sheffield, S3 7HF, UK., Fricero P; Department of Chemistry, University of Sheffield, Sheffield, S3 7HF, UK., Kopf KPM; Department of Chemistry, University of Sheffield, Sheffield, S3 7HF, UK., McColl EJ; Department of Chemistry, University of Sheffield, Sheffield, S3 7HF, UK., Czechtizky W; Integrated Drug discovery, R&D, Sanofi Aventis (Deutschland) GmbH, Industriepark Höchst, 65926, Frankfurt am Main, Germany.; Present address: Department of Medicinal Chemistry, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Pepparedsleden 1, 43183, Mölndal, Sweden., Lim YH; Functional Molecules & Polymers, Institute of Chemical and Engineering Sciences, A*STAR, Biopolis, Singapore, Singapore., Harrity JPA; Department of Chemistry, University of Sheffield, Sheffield, S3 7HF, UK.

Publikováno v: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2021 Apr 19; Vol. 60 (17), pp. 9412-9415. Date of Electronic Publication: 2021 Mar 17.

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