Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Freyr Jóhannsson"'
Autor:
Freyr Jóhannsson, James T. Yurkovich, Steinn Guðmundsson, Ólafur E. Sigurjónsson, Óttar Rolfsson
Publikováno v:
Metabolites, Vol 14, Iss 2, p 91 (2024)
Temperature plays a fundamental role in biology, influencing cellular function, chemical reaction rates, molecular structures, and interactions. While the temperature dependence of many biochemical reactions is well defined in vitro, the effect of te
Externí odkaz:
https://doaj.org/article/9bfd54caf5d64a4fa3f6fc37421be371
Autor:
Lea F. Buchweitz, James T. Yurkovich, Christoph Blessing, Veronika Kohler, Fabian Schwarzkopf, Zachary A. King, Laurence Yang, Freyr Jóhannsson, Ólafur E. Sigurjónsson, Óttar Rolfsson, Julian Heinrich, Andreas Dräger
Publikováno v:
BMC Bioinformatics, Vol 21, Iss 1, Pp 1-10 (2020)
Abstract Background New technologies have given rise to an abundance of -omics data, particularly metabolomic data. The scale of these data introduces new challenges for the interpretation and extraction of knowledge, requiring the development of inn
Externí odkaz:
https://doaj.org/article/d6b35fc262944f6188fb91f69512f3df
Autor:
Olafur E. Sigurjonsson, Ottar Rolfsson, Freyr Jóhannsson, Sveinn Guðmundsson, Niels Arni Arnason, Ragna Landrö
Publikováno v:
Transfusion. 60:367-377
Background The risk of bacterial contamination and the deterioration of platelet (PLT) quality limit the shelf-life of platelet concentrates (PCs). The INTERCEPT pathogen inactivation system reduces the risk of pathogen transmission by inhibiting nuc
Publikováno v:
Planta medica. 88(11)
The lichen compound protolichesterinic acid (PA) has an anti-proliferative effect against several cancer cell lines of different origin. This effect cannot be explained by the known inhibitory activity of PA against 5- and 12-lipoxygenases. The aim w
Autor:
Kotryna Seip, Ottar Rolfsson, Maria Tunset Grinde, Qiong Wang, Siver Andreas Moestue, Skarphedinn Halldorsson, Gunhild Mari Mælandsmo, Freyr Jóhannsson, Arnar Sigurdsson, Sigurdur Trausti Karvelsson
Background: Epithelial-to-mesenchymal transition (EMT) is a fundamental developmental process with strong implications in cancer progression. Understanding the metabolic alterations associated with EMT may open new avenues of treatment and prevention
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8078047cbda13f5b01f6a2d246cb751d
https://doi.org/10.21203/rs.3.rs-100299/v1
https://doi.org/10.21203/rs.3.rs-100299/v1
Autor:
Skarphedinn Halldorsson, Maria Tunset Grinde, Ottar Rolfsson, Qiong Wang, Sigurdur Trausti Karvelsson, Kotryna Seip, Gunhild Marie Maelandsmo, Freyr Jóhannsson, Siver Andreas Moestue, Arnar Sigurdsson
Publikováno v:
Molecular Cancer Research
Epithelial-to-mesenchymal transition (EMT) is a fundamental developmental process with strong implications in cancer progression. Understanding the metabolic alterations associated with EMT may open new avenues of treatment and prevention. Here we us
Autor:
Jón Freyr Jóhannsson
Publikováno v:
INTED Proceedings.
Autor:
Aarash Bordbar, Freyr Jóhannsson, Manuela Magnusdottir, Bernhard O. Palsson, Sigurður Brynjólfsson, Giuseppe Paglia, Sirus Palsson, Olafur E. Sigurjonsson, Ottar Rolfsson, Sveinn Guðmundsson
Publikováno v:
Transfusion. 57:2665-2676
BACKGROUND Alternate sugar metabolism during red blood cell (RBC) storage is not well understood. Here we report fructose and mannose metabolism in RBCs during cold storage in SAGM and the impact that these monosaccharides have on metabolic biomarker
Autor:
Sveinn Guðmundsson, Freyr Jóhannsson, Ottar Rolfsson, James T. Yurkovich, Olafur E. Sigurjonsson
Temperature plays a fundamental role in biology, influencing cellular function, affecting chemical reaction rates, molecular structures, and interactions. While the temperature dependence of many biochemical reactions is well definedin vitro, the eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d130f345f6881c8f3fc425c973c137e5
https://doi.org/10.1101/802660
https://doi.org/10.1101/802660
Systems analysis of metabolism in platelet concentrates during storage in platelet additive solution
Autor:
Sveinn Guðmundsson, Olafur E. Sigurjonsson, Steinn Guðmundsson, Bernhard O. Palsson, Ottar Rolfsson, Freyr Jóhannsson, Giuseppe Paglia
Publikováno v:
The Biochemical journal. 475(13)
Platelets (PLTs) deteriorate over time when stored within blood banks through a biological process known as PLT storage lesion (PSL). Here, we describe the refinement of the biochemical model of PLT metabolism, iAT-PLT-636, and its application to des