Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Freya Bruveris"'
Autor:
Rhys J.P. Skelton, Magdaline Costa, David J. Anderson, Freya Bruveris, Ben W. Finnin, Katerina Koutsis, Deevina Arasaratnam, Anthony J. White, Arash Rafii, Elizabeth S. Ng, Andrew G. Elefanty, Edouard G. Stanley, Colin W. Pouton, John M. Haynes, Reza Ardehali, Richard P. Davis, Christine L. Mummery, David A. Elliott
Publikováno v:
Stem Cell Research, Vol 13, Iss 1, Pp 172-179 (2014)
The study of human cardiogenesis would benefit from a detailed cell lineage fate map akin to that established for the haematopoietic lineages. Here we sought to define cell lineage relationships based on the expression of NKX2-5 and the cell surface
Externí odkaz:
https://doaj.org/article/5a705f1660c946f484ef5ef83c7f2db2
Autor:
Freya Bruveris, Jacqueline V. Schiesser, Andrew G. Elefanty, Tyrone Chen, Santhosh V. Kumar, Ali Motazedian, Elizabeth Ng, Christine A. Wells, Ann P. Chidgey, Edouard G. Stanley
Publikováno v:
Nature Cell Biology. 22:60-73
Defining the ontogeny of the human adaptive immune system during embryogenesis has implications for understanding childhood diseases including leukaemias and autoimmune conditions. Using RAG1:GFP human pluripotent stem cell reporter lines, we examine
Autor:
Freya Bruveris, Andrew Elefanty, Ana Rita Leitoguinho, Ali Motazedian, Elizabeth Ng, Koula Sourris, Edouard Stanley, Katerina Vlahos
Publikováno v:
Experimental Hematology. 111:S65-S66
Autor:
Edouard G. Stanley, Ana Rita Leitoguinho, Lisa Azzola, N. Davidson, Alicia Oshlack, Penelope McDonald, Ali Motazedian, Andrew G. Elefanty, Elizabeth Ng, Robyn Mayberry, Katerina Vlahos, Koula Sourris, Freya Bruveris
Publikováno v:
Development (Cambridge, England)
article-version (VoR) Version of Record
article-version (VoR) Version of Record
The genetic regulatory network controlling early fate choices during human blood cell development are not well understood. We used human pluripotent stem cell reporter lines to track the development of endothelial and haematopoietic populations in an
Publikováno v:
Experimental Hematology. 103:30-39.e2
Exogenous growth factors play an important role in mediating hematopoietic differentiation of human pluripotent stem cells. We explored the role of different factors in early human blood cell production using blast colony formation in methylcellulose
Autor:
Freya Bruveris, Andrew Elefanty, Ana Rita Leitoguinho, Ali Motazedian, Elizabeth Ng, Koula Sourris, Ed Stanley, Katerina Vlahos
Publikováno v:
Experimental Hematology. 100:S45
Autor:
Vincenzo Calvanese, Magdaline Costa, Aude Conscience, Vanta J. Jokubaitis, Claire E Hirst, Katerina Vlahos, Alicia Oshlack, Belinda Phipson, Freya Bruveris, Brenda Williams, Hanna K. A. Mikkola, Simone Liebscher, Andrew G. Elefanty, Qing C Yu, Elizabeth Ng, Edouard G. Stanley, Vania Januar, Katja Schenke-Layland, Zhen Zhang, Richard Saffery, Susan K. Nilsson, David A. Elliott, Lisa Azzola, Jennifer Durnall, Steven Anthony Jackson, Jovana Maksimovic, David N. Haylock
Publikováno v:
Nature Biotechnology. 34:1168-1179
The ability to generate hematopoietic stem cells from human pluripotent cells would enable many biomedical applications. We find that hematopoietic CD34+ cells in spin embryoid bodies derived from human embryonic stem cells (hESCs) lack HOXA expressi
Autor:
Elizabeth Ng, Osmond Lao, Stanley Ed, Patrick Ralph, Robert E. Nordon, Jingjing Li, Freya Bruveris, Andrew G. Elefanty
Publikováno v:
Experimental Hematology. 76:S73-S74
This study aims to characterise the effect of fluid shear stress on human embryonic stem cell (hESC)-derived haematopoiesis and vasculogenesis by applying microfluidics, live cell imaging and single cell RNA sequencing. AGM-like haematopoietic cultur
Autor:
Edouard G. Stanley, Santhosh V. Kumar, Freya Bruveris, Ann P. Chidgey, Elizabeth Ng, Ali Motazedian, Christine A. Wells, Andrew G. Elefanty, Tyrone Chen, Jacqueline V. Schiesser
Publikováno v:
Experimental Hematology. 76:e5
Defining the ontogeny of the human adaptive immune system during early embryogenesis has implications for understanding childhood diseases including leukemias and autoimmune diseases. Using RAG1:GFP human pluripotent stem cell reporter lines, we exam
Autor:
Koula Sourris, Kiymet Bozaoglu, Freya Bruveris, Penelope McDonald, Edouard G. Stanley, Andrew G. Elefanty, Robyn Mayberry, Katerina Vlahos, Jacqueline V. Schiesser, Paul J. Lockhart
Publikováno v:
Stem Cell Research, Vol 34, Iss, Pp-(2019)
We describe the generation and characterization of 5 human induced pluripotent stem cell (iPSC) lines derived from peripheral blood mononuclear cells (PBMCs) of healthy adult individuals. The PBMCs were reprogrammed using non-integrating Sendai virus