Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Freya, Harrison"'
Autor:
Claudia Simm, Tzong-Hsien Lee, Harshini Weerasinghe, Dean Walsh, Ioanna T. Nakou, Madhu Shankar, Wai Chung Tse, Yu Zhang, Rebecca Inman, Roger J. Mulder, Freya Harrison, Marie-Isabel Aguilar, Gregory L. Challis, Ana Traven
Publikováno v:
mBio, Vol 15, Iss 11 (2024)
ABSTRACT Amphotericin B (AmpB) is an effective but toxic antifungal drug. Thus, improving its activity/toxicity relationship is of interest. AmpB disrupts fungal membranes by two proposed mechanisms: ergosterol sequestration from the membrane and por
Externí odkaz:
https://doaj.org/article/19fb737237544dd1ace8e32c2584b530
Autor:
Elizabeth M. Darby, Robert A. Moran, Emma Holden, Theresa Morris, Freya Harrison, Barbara Clough, Ross S. McInnes, Ludwig Schneider, Eva M. Frickel, Mark A. Webber, Jessica M. A. Blair
Publikováno v:
mSphere, Vol 9, Iss 5 (2024)
ABSTRACT The two species that account for most cases of Acinetobacter-associated bacteremia in the United Kingdom are Acinetobacter lwoffii, often a commensal but also an emerging pathogen, and Acinetobacter baumannii, a well-known antibiotic-resista
Externí odkaz:
https://doaj.org/article/8d374d5b7f504bbaa70c039e941064e4
Autor:
Ramón Garcia Maset, Alexia Hapeshi, John Lapage, Niamh Harrington, Jenny Littler, Sébastien Perrier, Freya Harrison
Publikováno v:
npj Biofilms and Microbiomes, Vol 9, Iss 1, Pp 1-17 (2023)
Abstract Biofilm infections are associated with a high mortality risk for patients. Antibiotics perform poorly against biofilm communities, so high doses and prolonged treatments are often used in clinical settings. We investigated the pairwise inter
Externí odkaz:
https://doaj.org/article/18d8da64cf6b44fb84d7ee93d6c60bed
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract New antibiotics are urgently needed to reduce the health burden of antibiotic-resistant bacterial infection. Natural products (NPs) derived from plants and animals are a current focus of research seeking to discover new antibacterial molecul
Externí odkaz:
https://doaj.org/article/4261743306ae42ff87d8f6503ca1292f
Publikováno v:
Microorganisms, Vol 12, Iss 4, p 732 (2024)
Growth environment greatly alters many facets of pathogen physiology, including pathogenesis and antimicrobial tolerance. The importance of host-mimicking environments for attaining an accurate picture of pathogen behaviour is widely recognised. Whil
Externí odkaz:
https://doaj.org/article/7d7aa20178174c81b05deacde087ca3d
Autor:
Ramón Garcia Maset, Alexia Hapeshi, John Lapage, Niamh Harrington, Jenny Littler, Sébastien Perrier, Freya Harrison
Publikováno v:
npj Biofilms and Microbiomes, Vol 9, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/02cc73f1abb846d3bfe7820490e9b9be
Autor:
George A. O’Toole, Aurélie Crabbé, Rolf Kümmerli, John J. LiPuma, Jennifer M. Bomberger, Jane C. Davies, Dominique Limoli, Vanessa V. Phelan, James B. Bliska, William H. DePas, Lars E. Dietrich, Thomas H. Hampton, Ryan Hunter, Cezar M. Khursigara, Alexa Price-Whelan, Alix Ashare, Robert A. Cramer, Joanna B. Goldberg, Freya Harrison, Deborah A. Hogan, Michael A. Henson, Dean R. Madden, Jared R. Mayers, Carey Nadell, Dianne Newman, Alice Prince, Damian W. Rivett, Joseph D. Schwartzman, Daniel Schultz, Donald C. Sheppard, Alan R. Smyth, Melanie A. Spero, Bruce A. Stanton, Paul E. Turner, Chris van der Gast, Fiona J. Whelan, Rachel Whitaker, Katrine Whiteson
Publikováno v:
mBio, Vol 12, Iss 5 (2021)
A recent workshop titled “Developing Models to Study Polymicrobial Infections,” sponsored by the Dartmouth Cystic Fibrosis Center (DartCF), explored the development of new models to study the polymicrobial infections associated with the airways o
Externí odkaz:
https://doaj.org/article/1ed07d7593e74bbf8897df772ce78eb2
Publikováno v:
F1000Research, Vol 10 (2021)
The airways of people with cystic fibrosis (CF) are often chronically colonised with a diverse array of bacterial and fungal species. However, little is known about the relative partitioning of species between the planktonic and biofilm modes of grow
Externí odkaz:
https://doaj.org/article/a55c3b4bd15248e48fb5015413590e40
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Externí odkaz:
https://doaj.org/article/8e55c8f746b242b692be53497547f0b1
Publikováno v:
Biofilm, Vol 2, Iss , Pp 100024- (2020)
Pseudomonas aeruginosa biofilm infections in the cystic fibrosis (CF) lung are highly resistant to current antimicrobial treatments and are associated with increased mortality rates. The existing models for such infections are not able to reliably mi
Externí odkaz:
https://doaj.org/article/cff15820f8f24b66ab48f349fc690a12