Intranasal delivery of transforming growth factor-beta1 in mice after stroke reduces infarct volume and increases neurogenesis in the subventricular zone.

Autor: Ma M, Ma Y, Yi X, Guo R, Zhu W, Fan X, Xu G, Frey WH 2nd, Liu X, Ma, Minmin, Ma, Yuping, Yi, Xueming, Guo, Ruibing, Zhu, Wusheng, Fan, Xinying, Xu, Gelin, Frey, William H 2nd, Liu, Xinfeng

Publikováno v: BMC Neuroscience; 2008, Vol. 9, p117-117, 1p

Brain Glucose Hypometabolism and Iron Accumulation in Different Brain Regions in Alzheimer's and Parkinson's Diseases.

Autor: Rao IY; HealthPartners Center for Memory and Aging, 295 Phalen Boulevard, St. Paul, MN 55130, USA., Hanson LR; HealthPartners Center for Memory and Aging, 295 Phalen Boulevard, St. Paul, MN 55130, USA.; HealthPartners Institute, Bloomington, MN 55425, USA., Johnson JC; HealthPartners Struthers Parkinson's Center, Minneapolis, MN 55427, USA., Rosenbloom MH; HealthPartners Center for Memory and Aging, 295 Phalen Boulevard, St. Paul, MN 55130, USA., Frey WH 2nd; HealthPartners Center for Memory and Aging, 295 Phalen Boulevard, St. Paul, MN 55130, USA.; HealthPartners Institute, Bloomington, MN 55425, USA.

Publikováno v: Pharmaceuticals (Basel, Switzerland) [Pharmaceuticals (Basel)] 2022 Apr 29; Vol. 15 (5). Date of Electronic Publication: 2022 Apr 29.

Comparative Effectiveness of Intracerebroventricular, Intrathecal, and Intranasal Routes of AAV9 Vector Administration for Genetic Therapy of Neurologic Disease in Murine Mucopolysaccharidosis Type I.

Autor: Belur LR; Department of Genetics, Cell Biology and Development, Center for Genome Engineering, University of Minnesota, Minneapolis, MN, United States., Romero M; Department of Genetics, Cell Biology and Development, Center for Genome Engineering, University of Minnesota, Minneapolis, MN, United States., Lee J; Department of Genetics, Cell Biology and Development, Center for Genome Engineering, University of Minnesota, Minneapolis, MN, United States., Podetz-Pedersen KM; Department of Genetics, Cell Biology and Development, Center for Genome Engineering, University of Minnesota, Minneapolis, MN, United States., Nan Z; Department of Neurosurgery and Graduate Program in Neuroscience, University of Minnesota, Minneapolis, MN, United States., Riedl MS; Department of Neuroscience, University of Minnesota, Minneapolis, MN, United States., Vulchanova L; Department of Neuroscience, University of Minnesota, Minneapolis, MN, United States., Kitto KF; Department of Pharmaceutics, University of Minnesota, Minneapolis, MN, United States., Fairbanks CA; Department of Pharmaceutics, University of Minnesota, Minneapolis, MN, United States., Kozarsky KF; REGENXBIO Inc., Rockville, MD, United States., Orchard PJ; Division of Blood and Marrow Transplantation, Department of Pediatrics, University of Minnesota, Minneapolis, MN, United States., Frey WH 2nd; HealthPartners Neurosciences, Regions Hospital, St. Paul, MN, United States., Low WC; Department of Neurosurgery and Graduate Program in Neuroscience, University of Minnesota, Minneapolis, MN, United States., McIvor RS; Department of Genetics, Cell Biology and Development, Center for Genome Engineering, University of Minnesota, Minneapolis, MN, United States.

Publikováno v: Frontiers in molecular neuroscience [Front Mol Neurosci] 2021 May 10; Vol. 14, pp. 618360. Date of Electronic Publication: 2021 May 10 (Print Publication: 2021).

Cell motility and migration as determinants of stem cell efficacy.

Autor: Danielyan L; Department of Clinical Pharmacology, University Hospital Tübingen, Tübingen, Germany; Neuroscience Laboratory and Departments of Biochemistry and Clinical Pharmacology, Yerevan State Medical University, Yerevan, Armenia. Electronic address: lusine.danielyan@med.uni-tuebingen.de., Schwab M; Department of Clinical Pharmacology, University Hospital Tübingen, Tübingen, Germany; Neuroscience Laboratory and Departments of Biochemistry and Clinical Pharmacology, Yerevan State Medical University, Yerevan, Armenia; Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany and University of Tübingen, Tübingen, Germany; Department of Pharmacy and Biochemistry, University of Tübingen, Tübingen, Germany., Siegel G; Institute of Clinical and Experimental Transfusion Medicine, University Hospital Tübingen, Tübingen, Germany., Brawek B; Institute of Physiology, Department of Neurophysiology, University of Tübingen, Tübingen, Germany., Garaschuk O; Institute of Physiology, Department of Neurophysiology, University of Tübingen, Tübingen, Germany., Asavapanumas N; Institute of Physiology, Department of Neurophysiology, University of Tübingen, Tübingen, Germany., Buadze M; Department of Clinical Pharmacology, University Hospital Tübingen, Tübingen, Germany., Lourhmati A; Department of Clinical Pharmacology, University Hospital Tübingen, Tübingen, Germany., Wendel HP; Department of Thoracic, Cardiac and Vascular Surgery, University Hospital Tübingen, Tübingen, Germany., Avci-Adali M; Department of Thoracic, Cardiac and Vascular Surgery, University Hospital Tübingen, Tübingen, Germany., Krueger MA; Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, University Hospital Tübingen, Tübingen, Germany., Calaminus C; Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, University Hospital Tübingen, Tübingen, Germany., Naumann U; Hertie Institute for Clinical Brain Research and Center Neurology, Department of Vascular Neurology, Tübingen Neuro-Campus (TNC), University of Tübingen, Tübingen, Germany., Winter S; Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany and University of Tübingen, Tübingen, Germany., Schaeffeler E; Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany and University of Tübingen, Tübingen, Germany., Spogis A; Department of Clinical Pharmacology, University Hospital Tübingen, Tübingen, Germany., Beer-Hammer S; Department of Pharmacology, Experimental Therapy and Toxicology, Institute of Experimental and Clinical Pharmacology and Pharmacogenomic, and ICePhA, University Hospital Tübingen, Tübingen, Germany., Neher JJ; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Tübingen, Germany., Spohn G; Institute for Transfusion Medicine and Immunohematology, German Red Cross Blood Donor Service Baden-Württemberg-Hessen gGmbH, Goethe-University Hospital, Frankfurt am Main, Germany., Kretschmer A; Institute for Transfusion Medicine and Immunohematology, German Red Cross Blood Donor Service Baden-Württemberg-Hessen gGmbH, Goethe-University Hospital, Frankfurt am Main, Germany., Krämer-Albers EM; Institute for Developmental Biology and Neurobiology, Johannes Gutenberg University Mainz, Mainz, Germany., Barth K; Institute for Developmental Biology and Neurobiology, Johannes Gutenberg University Mainz, Mainz, Germany., Lee HJ; College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Chungbuk, Republic of Korea; Research Institute eBiogen Inc., Seoul, Republic of Korea., Kim SU; Division of Neurology, Department of Medicine, UBC Hospital, University of British Columbia, Vancouver, BC, Canada., Frey WH 2nd; HealthPartners Center for Memory and Aging, HealthPartners Neurosciences, St. Paul, MN, U.S.A., Claussen CD; Department of Radiology, University Hospital Tübingen, Tübingen, Germany., Hermann DM; Department of Neurology, University of Duisburg-Essen, Essen, Germany., Doeppner TR; Department of Neurology, University of Duisburg-Essen, Essen, Germany; Department of Neurology, University Medical Center Göttingen, Göttingen, Germany., Seifried E; Institute for Transfusion Medicine and Immunohematology, German Red Cross Blood Donor Service Baden-Württemberg-Hessen gGmbH, Goethe-University Hospital, Frankfurt am Main, Germany., Gleiter CH; Department of Clinical Pharmacology, University Hospital Tübingen, Tübingen, Germany., Northoff H; Institute of Clinical and Experimental Transfusion Medicine, University Hospital Tübingen, Tübingen, Germany., Schäfer R; Institute of Clinical and Experimental Transfusion Medicine, University Hospital Tübingen, Tübingen, Germany; Institute for Transfusion Medicine and Immunohematology, German Red Cross Blood Donor Service Baden-Württemberg-Hessen gGmbH, Goethe-University Hospital, Frankfurt am Main, Germany. Electronic address: richard.schaefer.md@gmail.com.

Publikováno v: EBioMedicine [EBioMedicine] 2020 Oct; Vol. 60, pp. 102989. Date of Electronic Publication: 2020 Sep 10.

Intranasal deferoxamine can improve memory in healthy C57 mice, suggesting a partially non-disease-specific pathway of functional neurologic improvement.

Autor: Fine JM; Neuroscience Research at HealthPartners Institute, Saint Paul, MN, USA., Kosyakovsky J; Neuroscience Research at HealthPartners Institute, Saint Paul, MN, USA., Baillargeon AM; Neuroscience Research at HealthPartners Institute, Saint Paul, MN, USA., Tokarev JV; Neuroscience Research at HealthPartners Institute, Saint Paul, MN, USA., Cooner JM; Neuroscience Research at HealthPartners Institute, Saint Paul, MN, USA., Svitak AL; Neuroscience Research at HealthPartners Institute, Saint Paul, MN, USA., Faltesek KA; Neuroscience Research at HealthPartners Institute, Saint Paul, MN, USA., Frey WH 2nd; Neuroscience Research at HealthPartners Institute, Saint Paul, MN, USA., Hanson LR; Neuroscience Research at HealthPartners Institute, Saint Paul, MN, USA.

Publikováno v: Brain and behavior [Brain Behav] 2020 Mar; Vol. 10 (3), pp. e01536. Date of Electronic Publication: 2020 Jan 20.