Divalent cations promote huntingtin fibril formation on endoplasmic reticulum derived and model membranes.

Autor: Skeens A; The C. Eugene Bennett Department of Chemistry, West Virginia University, 217 Clark Hall, Morgantown, WV 26506, USA., Markle JM; The Department of Chemistry, Gettysburg College, 300 N. Washington Street, Gettysburg, PA 17325, USA., Petipas G; The C. Eugene Bennett Department of Chemistry, West Virginia University, 217 Clark Hall, Morgantown, WV 26506, USA., Frey SL; The Department of Chemistry, Gettysburg College, 300 N. Washington Street, Gettysburg, PA 17325, USA. Electronic address: sfrey@gettysburg.edu., Legleiter J; The C. Eugene Bennett Department of Chemistry, West Virginia University, 217 Clark Hall, Morgantown, WV 26506, USA; Rockefeller Neurosciences Institutes, West Virginia University, 1 Medical Center Dr., P.O. Box 9303, Morgantown, WV 26505, USA; Department of Neuroscience, West Virginia University, 1 Medical Center Dr., P.O. Box 9303, Morgantown, WV 26505, USA. Electronic address: justin.legleiter@mail.wvu.edu.

Publikováno v: Biochimica et biophysica acta. Biomembranes [Biochim Biophys Acta Biomembr] 2024 Aug; Vol. 1866 (6), pp. 184339. Date of Electronic Publication: 2024 May 18.

The polyglutamine domain is the primary driver of seeding in huntingtin aggregation.

Autor: Skeens A; The C. Eugene Bennett Department of Chemistry, West Virginia University, Morgantown, West Virginia, United States of America., Siriwardhana C; The C. Eugene Bennett Department of Chemistry, West Virginia University, Morgantown, West Virginia, United States of America., Massinople SE; The C. Eugene Bennett Department of Chemistry, West Virginia University, Morgantown, West Virginia, United States of America., Wunder MM; The C. Eugene Bennett Department of Chemistry, West Virginia University, Morgantown, West Virginia, United States of America., Ellis ZL; The C. Eugene Bennett Department of Chemistry, West Virginia University, Morgantown, West Virginia, United States of America., Keith KM; The C. Eugene Bennett Department of Chemistry, West Virginia University, Morgantown, West Virginia, United States of America., Girman T; The C. Eugene Bennett Department of Chemistry, West Virginia University, Morgantown, West Virginia, United States of America., Frey SL; The Department of Chemistry, Gettysburg College, Gettysburg, Pennsylvania, United States of America., Legleiter J; The C. Eugene Bennett Department of Chemistry, West Virginia University, Morgantown, West Virginia, United States of America.; Rockefeller Neurosciences Institutes, West Virginia University, Morgantown, West Virginia, United States of America.; Department of Neuroscience, West Virginia University, Morgantown, West Virginia, United States of America.

Publikováno v: PloS one [PLoS One] 2024 Mar 14; Vol. 19 (3), pp. e0298323. Date of Electronic Publication: 2024 Mar 14 (Print Publication: 2024).

Enhanced Ordering in Monolayers Containing Glycosphingolipids: Impact of Carbohydrate Structure.

Autor: Watkins EB; MPA/CINT/Manual Lujan Jr. Neutron Scattering Center, Los Alamos National Laboratory, Los Alamos, New Mexico., Frey SL; Department of Chemistry, Gettysburg College, Gettysburg, Pennsylvania; Department of Chemistry, Institute for Biophysical Dynamics, and James Franck Institute, The University of Chicago, Chicago, Illinois., Chi EY; Department of Chemistry, Institute for Biophysical Dynamics, and James Franck Institute, The University of Chicago, Chicago, Illinois; Department of Chemical and Biological Engineering and the Center for Biomedical Engineering, University of New Mexico, Albuquerque, New Mexico., Cao KD; Department of Chemistry, Institute for Biophysical Dynamics, and James Franck Institute, The University of Chicago, Chicago, Illinois., Pacuszka T; Department of Biochemistry and Molecular Biology, Medical Center of Postgraduate Education, Warsaw, Poland., Majewski J; MPA/CINT/Manual Lujan Jr. Neutron Scattering Center, Los Alamos National Laboratory, Los Alamos, New Mexico; Department of Chemical Engineering, University of California Davis, Davis, California. Electronic address: jmajewsk@nsf.gov., Lee KYC; Department of Chemistry, Institute for Biophysical Dynamics, and James Franck Institute, The University of Chicago, Chicago, Illinois. Electronic address: kayeelee@uchicago.edu.

Publikováno v: Biophysical journal [Biophys J] 2018 Mar 13; Vol. 114 (5), pp. 1103-1115.

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