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Exploring novel HIV-1 reverse transcriptase inhibitors with drug-resistant mutants: A double mutant surprise.

Autor: Hollander K; Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, Connecticut, USA.; Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut, USA., Chan AH; Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut, USA., Frey KM; Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut, USA., Hunker O; Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, Connecticut, USA., Ippolito JA; Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut, USA.; Department of Chemistry, Yale University, New Haven, Connecticut, USA., Spasov KA; Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut, USA., Yeh YJ; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, Connecticut, USA., Jorgensen WL; Department of Chemistry, Yale University, New Haven, Connecticut, USA., Ho YC; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, Connecticut, USA., Anderson KS; Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, Connecticut, USA.; Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut, USA.

Publikováno v: Protein science : a publication of the Protein Society [Protein Sci] 2023 Dec; Vol. 32 (12), pp. e4814.

Early testicular maturation is sensitive to depletion of spermatogonial pool in sickle cell disease.

Autor: Benninghoven-Frey KM; Centre of Reproductive Medicine and Andrology, University of Münster and University Clinic Münster, Münster., Neuhaus N; Centre of Reproductive Medicine and Andrology, University of Münster and University Clinic Münster, Münster., Lahtinen AK; Applied Tumor Genomics Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland; Department of Medical and Clinical Genetics / Medicum, Faculty of Medicine, University of Helsinki, Helsinki., Krallmann C; Centre of Reproductive Medicine and Andrology, University of Münster and University Clinic Münster, Münster., Portela JMD; Center for Reproductive Medicine, Research Institute Reproduction and Development, Amsterdam Universitair Medische Centra, University of Amsterdam, Amsterdam., Jarisch A; Division of Stem Cell Transplantation and Immunology, Department of Children and Adolescent Medicine, University Hospital Frankfurt, Johann Wolfgang Goethe University, Frankfurt am Main., Nordhoff V; Centre of Reproductive Medicine and Andrology, University of Münster and University Clinic Münster, Münster., Soave A; Department of Urology, University Medical Center Hamburg-Eppendorf, Hamburg., Ba Omar HAM; NORDFERTIL Research Lab Stockholm, Department of Women's and Children's Health, Karolinska Institutet, and Karolinska University Hospital, Stockholm., Sundin M; Division of Paediatrics, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden; Section of Hematology, Immunology and HCT, Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm., Langenskiöld C; Department of Pediatric Oncology, The Queen Silvia Children's Hospital, Gothenburg., Kliesch S; Centre of Reproductive Medicine and Andrology, University of Münster and University Clinic Münster, Münster., Stukenborg JB; NORDFERTIL Research Lab Stockholm, Department of Women's and Children's Health, Karolinska Institutet, and Karolinska University Hospital, Stockholm., Jahnukainen K; NORDFERTIL Research Lab Stockholm, Department of Women's and Children's Health, Karolinska Institutet, and Karolinska University Hospital, Stockholm, Sweden; New Children's Hospital, Paediatric Research Centre, University of Helsinki and Helsinki University Hospital, Helsinki. Kirsi.Jahnukainen@ki.se.

Publikováno v: Haematologica [Haematologica] 2022 Apr 01; Vol. 107 (4), pp. 975-979. Date of Electronic Publication: 2022 Apr 01.

Clascoterone: A Novel Topical Androgen Receptor Inhibitor for the Treatment of Acne.

Autor: Kalabalik-Hoganson J; Fairleigh Dickinson University School of Pharmacy and Health Sciences, Florham Park, NJ, USA., Frey KM; Fairleigh Dickinson University School of Pharmacy and Health Sciences, Florham Park, NJ, USA., Ozdener-Poyraz AE; Fairleigh Dickinson University School of Pharmacy and Health Sciences, Florham Park, NJ, USA., Slugocki M; Fairleigh Dickinson University School of Pharmacy and Health Sciences, Florham Park, NJ, USA.

Publikováno v: The Annals of pharmacotherapy [Ann Pharmacother] 2021 Oct; Vol. 55 (10), pp. 1290-1296. Date of Electronic Publication: 2021 Feb 03.

Limonene-induced activation of A 2A adenosine receptors reduces airway inflammation and reactivity in a mouse model of asthma.

Autor: Patel M; Division of Pharmaceutical Sciences Arnold & Marie Schwartz College of Pharmacy & Health Sciences, Long Island University, Brooklyn, NY, USA., Narke D; Division of Pharmaceutical Sciences Arnold & Marie Schwartz College of Pharmacy & Health Sciences, Long Island University, Brooklyn, NY, USA., Kurade M; Division of Pharmaceutical Sciences Arnold & Marie Schwartz College of Pharmacy & Health Sciences, Long Island University, Brooklyn, NY, USA., Frey KM; Fairleigh Dickinson University School of Pharmacy and Health Sciences, Teaneck, NJ, USA., Rajalingam S; Division of Pharmaceutical Sciences Arnold & Marie Schwartz College of Pharmacy & Health Sciences, Long Island University, Brooklyn, NY, USA., Siddiquee A; Division of Pharmaceutical Sciences Arnold & Marie Schwartz College of Pharmacy & Health Sciences, Long Island University, Brooklyn, NY, USA., Mustafa SJ; Department of Physiology and Pharmacology, West Virginia University, Morgantown, WV, USA., Ledent C; Université Libre de Bruxelles, Brussels, Belgium., Ponnoth DS; Division of Pharmaceutical Sciences Arnold & Marie Schwartz College of Pharmacy & Health Sciences, Long Island University, Brooklyn, NY, USA. dponnoth@osteo.wvsom.edu.; Department of Biomedical Sciences, West Virginia School of Osteopathic Medicine, WV, Lewisburg, USA. dponnoth@osteo.wvsom.edu.

Publikováno v: Purinergic signalling [Purinergic Signal] 2020 Sep; Vol. 16 (3), pp. 415-426. Date of Electronic Publication: 2020 Aug 13.