‘Pergularain e I’ – a plant cysteine protease with thrombin-like activity from Pergularia extensa latex

Autor: Shivaprasad, Holenarasipura V., Rajaiah, Rajesh, Frey, Brigitte M., Frey, Felix J., Vishwanath, Bannikuppe S.

Publikováno v: In Thrombosis Research 2010 125(3):e100-e105

Mechanism of the Dual Activities of Human CYP17A1 and Binding to Anti-Prostate Cancer Drug Abiraterone Revealed by a Novel V366M Mutation Causing 17,20 Lyase Deficiency

Autor: Fernández Cancio, Mónica, Camats Tarruella, Núria, Flück, Christa E., Zalewski, Adam, Dick, Bernhard, Frey, Brigitte M., Monné, Raquel, Torán, Núria, Audí, Laura, Pandey, Amit V., Universitat Autònoma de Barcelona

Publikováno v: Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Pharmaceuticals
Pharmaceuticals; Volume 11; Issue 2; Pages: 37
Pharmaceuticals, Vol 11, Iss 2, p 37 (2018)
Fernández-Cancio, Mónica; Camats Tarruella, Núria; Flück Pandey, Christa Emma; Zalewski, Adam; Dick, Bernhard; Frey-von Matt, Brigitte; Monné, Raquel; Torán, Núria; Audí, Laura; Pandey, Amit Vikram (2018). Mechanism of the Dual Activities of Human CYP17A1 and Binding to Anti-Prostate Cancer Drug Abiraterone Revealed by a Novel V366M Mutation Causing 17,20 Lyase Deficiency. Pharmaceuticals, 11(2), p. 37. MDPI 10.3390/ph11020037

The CYP17A1 gene regulates sex steroid biosynthesis in humans through 17α-hydroxylase/17,20 lyase activities and is a target of anti-prostate cancer drug abiraterone. In a 46, XY patient with female external genitalia, together with a loss of functi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d8ac07a6e9b6f36ca3ab02c5374e833
https://ddd.uab.cat/record/253512

Role of the α-adducin genotype on renal disease progression

Autor: Nicod, Jérôme ^*, Frey, Brigitte M., Frey, Felix J., Ferrari, Paolo

Publikováno v: In Kidney International April 2002 61(4):1270-1275

Age-dependent Decrease in 11β-Hydroxysteroid Dehydrogenase Type 2 (11β-HSD2) Activity in Hypertensive Patients

Autor: Henschkowski, Jana, Stuck, Andreas E., Frey, Brigitte M., Gillmann, Gerhard, Dick, Bernhard, Frey, Felix J., Mohaupt, Markus G.

Background The prevalence of arterial hypertension lacking a defined underlying cause increases with age. Age-related arterial hypertension is insufficiently understood, yet known characteristics suggest an aldosterone-independent activation of the m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______805::11fbfcc60a912f5a6eb6ca708ae618dd
http://doc.rero.ch/record/304949/files/21_6_644.pdf

18F-RB390: innovative ligand for imaging the T877A androgen receptor mutant in prostate cancer via positron emission tomography (PET)

Autor: Bertolini, Reto, Goepfert, Christine, Andrieu, Thomas, Nichols, Sara, Walter, Martin A, Frey, Felix J, McCammon, J Andrew, Frey, Brigitte M

Publikováno v: The Prostate, vol 75, iss 4

BACKGROUND Detecting prostate cancer before spreading or predicting a favorable therapy are challenging issues for impacting patient's survival. Presently, 2-[(18) F]-fluoro-2-deoxy-D-glucose ((18) F-FDG) and/or (18) F-fluorocholine ((18) F-FCH) are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74e5fe527a7a6173e8acc2c85e465411