‘Pergularain e I’ – a plant cysteine protease with thrombin-like activity from Pergularia extensa latex

Autor: Shivaprasad, Holenarasipura V., Rajaiah, Rajesh, Frey, Brigitte M., Frey, Felix J., Vishwanath, Bannikuppe S.

Publikováno v: In Thrombosis Research 2010 125(3):e100-e105

Mechanism of the Dual Activities of Human CYP17A1 and Binding to Anti-Prostate Cancer Drug Abiraterone Revealed by a Novel V366M Mutation Causing 17,20 Lyase Deficiency

Autor: Fernández Cancio, Mónica, Camats Tarruella, Núria, Flück, Christa E., Zalewski, Adam, Dick, Bernhard, Frey, Brigitte M., Monné, Raquel, Torán, Núria, Audí, Laura, Pandey, Amit V., Universitat Autònoma de Barcelona

Publikováno v: Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Pharmaceuticals
Pharmaceuticals; Volume 11; Issue 2; Pages: 37
Pharmaceuticals, Vol 11, Iss 2, p 37 (2018)
Fernández-Cancio, Mónica; Camats Tarruella, Núria; Flück Pandey, Christa Emma; Zalewski, Adam; Dick, Bernhard; Frey-von Matt, Brigitte; Monné, Raquel; Torán, Núria; Audí, Laura; Pandey, Amit Vikram (2018). Mechanism of the Dual Activities of Human CYP17A1 and Binding to Anti-Prostate Cancer Drug Abiraterone Revealed by a Novel V366M Mutation Causing 17,20 Lyase Deficiency. Pharmaceuticals, 11(2), p. 37. MDPI 10.3390/ph11020037

The CYP17A1 gene regulates sex steroid biosynthesis in humans through 17α-hydroxylase/17,20 lyase activities and is a target of anti-prostate cancer drug abiraterone. In a 46, XY patient with female external genitalia, together with a loss of functi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d8ac07a6e9b6f36ca3ab02c5374e833
https://ddd.uab.cat/record/253512

Role of the α-adducin genotype on renal disease progression

Autor: Nicod, Jérôme ^*, Frey, Brigitte M., Frey, Felix J., Ferrari, Paolo

Publikováno v: In Kidney International April 2002 61(4):1270-1275

Age-dependent Decrease in 11β-Hydroxysteroid Dehydrogenase Type 2 (11β-HSD2) Activity in Hypertensive Patients

Autor: Henschkowski, Jana, Stuck, Andreas E., Frey, Brigitte M., Gillmann, Gerhard, Dick, Bernhard, Frey, Felix J., Mohaupt, Markus G.

Background The prevalence of arterial hypertension lacking a defined underlying cause increases with age. Age-related arterial hypertension is insufficiently understood, yet known characteristics suggest an aldosterone-independent activation of the m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______805::11fbfcc60a912f5a6eb6ca708ae618dd
http://doc.rero.ch/record/304949/files/21_6_644.pdf

Insulin, CCAAT/enhancer-binding proteins and lactate regulate the human 11β-hydroxysteroid dehydrogenase type 2 gene expression in colon cancer cell lines

Autor: Andrieu, Thomas, Fustier, Pierre, Alikhani-Koupaei, Rasoul, Ignatova, Irena D, Guettinger, Andreas, Frey, Felix J, Frey, Brigitte M, Alikhani, Rasoul, Ignatova, Irena Darieva, Güttinger, Andreas, Frey, Felix, Frey, Brigitte

Publikováno v: PLoS ONE
PLoS ONE, Vol 9, Iss 8, p e105354 (2014)
Andrieu, Thomas; Fustier, Pierre; Alikhani-Koupaei, Rasoul; Ignatova, Irena D; Guettinger, Andreas; Frey, Felix J; Frey, Brigitte M; Andrieu, Thomas; Fustier, Pierre; Alikhani, Rasoul; Ignatova, Irena Darieva; Güttinger, Andreas; Frey, Felix; Frey, Brigitte (2014). Insulin, CCAAT/enhancer-binding proteins and lactate regulate the human 11β-hydroxysteroid dehydrogenase type 2 gene expression in colon cancer cell lines. PLoS ONE, 9(8), e105354. Public Library of Science 10.1371/journal.pone.0105354

11β-Hydroxysteroid dehydrogenases (11beta-HSD) modulate mineralocorticoid receptor transactivation by glucocorticoids and regulate access to the glucocorticoid receptor. The isozyme 11beta-HSD2 is selectively expressed in mineralocorticoid target ti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85b77cf3e4d239e3068c777035b037d1
https://pubmed.ncbi.nlm.nih.gov/25133511