Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Fresnida J. Ramos"'
Autor:
Ryan Rossner, Marissa Fletcher, Matt Kaeberlein, Scott F. Leiser, Alison Leonard, Melissa Primitivo, Fresnida J. Ramos, Dana L. Miller, Nicholas D. Rintala, Hillary Miller
Publikováno v:
Science. 350:1375-1378
Stabilization of the hypoxia-inducible factor 1 (HIF-1) increases life span and health span in nematodes through an unknown mechanism. We report that neuronal stabilization of HIF-1 mediates these effects in Caenorhabditis elegans through a cell nona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b888b3e0f7ca89095bf93c1b812d6900
https://doi.org/10.1126/science.aac9257
https://doi.org/10.1126/science.aac9257
Autor:
Feng Liu, Hak Joo Lee, Lily Q. Dong, Ruihua Xiang, Meilian Liu, Changhua Wang, Hongzhi Chen, Xuming Mao, Fresnida J. Ramos, Chintan K. Kikani, Xiaoban Xin
Publikováno v:
Journal of Biological Chemistry. 284:31608-31615
APPL1 is a newly identified adiponectin receptor-binding protein that positively mediates adiponectin signaling in cells. Here we report that APPL2, an isoform of APPL1 that forms a dimer with APPL1, can interacts with both AdipoR1 and AdipoR2 and ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a81c4b98cf780db00929cf9166d1d0d
https://doi.org/10.1074/jbc.m109.010355
https://doi.org/10.1074/jbc.m109.010355
Autor:
Lily Q. Dong, Bogdan Balas, Ryang Yeo Kim, Cuiling Li, Nicolas Musi, Ralph A. DeFronzo, Chintan K. Kikani, Chu-Xia Deng, Feng Liu, Lixin Wang, Fresnida J. Ramos, Sara M. Reyna, Christine Y. Christ-Roberts
Publikováno v:
Molecular and Cellular Biology. 27:6497-6505
Grb10 is a pleckstrin homology and Src homology 2 domain-containing protein that interacts with a number of phosphorylated receptor tyrosine kinases, including the insulin receptor. In mice, Grb10 gene expression is imprinted with maternal expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd4103ebc11331230ffd136f6a05fb1b
https://doi.org/10.1128/mcb.00679-07
https://doi.org/10.1128/mcb.00679-07
Autor:
Matt Kaeberlein, Ernst Bernhard Kayser, Melana E. Yanos, Lauren Uhde, Philip G. Morgan, Richard D. Palmiter, Simon C. Johnson, Kelly Oh, Maya Sangesland, Margaret M. Sedensky, Brian M. Wasko, Albert Quintana, Valerie Z. Wall, Peter S. Rabinovitch, Anthony S. Castanza, Fresnida J. Ramos, Arni Gagnidze, Jessica Hui
Publikováno v:
Science (New York, N.Y.). 342(6165)
More from mTOR Leigh syndrome is a rare, untreatable, inherited neurodegenerative disease in children that is caused by functional disruption of mitochondria, the cell's energy-producing organelles. Johnson et al. (p. 1524 , published online 14 Novem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb0fbbc97498d1c4abc33ab36b00f040
https://pubmed.ncbi.nlm.nih.gov/24357304
https://pubmed.ncbi.nlm.nih.gov/24357304
Autor:
Steven C. Chen, Randy Strong, Elroy H. An, Vivian L. MacKay, Chen-Yu Liao, Peter S. Rabinovitch, Warren C. Ladiges, Matt Kaeberlein, Dao-Fu Dai, Katherine H. Schreiber, Michael G. Garelick, Brian K. Kennedy, Fresnida J. Ramos
Publikováno v:
Science translational medicine. 4(144)
Mutations in LMNA, the gene that encodes A-type lamins, cause multiple diseases including dystrophies of the skeletal muscle and fat, dilated cardiomyopathy, and progeria-like syndromes (collectively termed laminopathies). Reduced A-type lamin functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e93e50b1825af97f659bfbb94e4ae7c1
https://pubmed.ncbi.nlm.nih.gov/22837538
https://pubmed.ncbi.nlm.nih.gov/22837538
Publikováno v:
Advances in experimental medicine and biology. 694
Appropriate regulation of mRNA translation is essential for growth and survival and the pathways that regulate mRNA translation have been highly conserved throughout eukaryotic evolution. Translation is controlled by a complex set of mechanisms actin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e27c2d544f8e6dafccf52e1918af0114
https://pubmed.ncbi.nlm.nih.gov/20886753
https://pubmed.ncbi.nlm.nih.gov/20886753
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781441970015
Appropriate regulation of mRNA translation is essential for growth and survival and the pathways that regulate mRNA translation have been highly conserved throughout eukaryotic evolution. Translation is controlled by a complex set of mechanisms actin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27a5e438fdd7d0f74f74dfb782947d98
https://doi.org/10.1007/978-1-4419-7002-2_2
https://doi.org/10.1007/978-1-4419-7002-2_2
Autor:
Alexander Huh, George L. Sutphin, Christina Davis, Lara S. Shamieh, Katherine A. Steinkraus, Devon Chandler-Brown, Ranjana Mehta, Fresnida J. Ramos, Matt Kaeberlein
Publikováno v:
Science (New York, N.Y.). 324(5931)
Anti-Aging Several human neurodegenerative diseases, such as Alzheimer's and Huntington's, are caused by aberrant protein aggregation. These disorders typically develop after the fifth decade of life, suggesting a connection with the aging process. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04c8ba63253e494f8d2ae16c9e3936d7
https://pubmed.ncbi.nlm.nih.gov/19372390
https://pubmed.ncbi.nlm.nih.gov/19372390
Autor:
Jingjing Zhang, Holly Van Remmen, Lily Q. Dong, Meilian Liu, Arlan Richardson, Xianling Liu, Xiang Bai, Fresnida J. Ramos, Fuyou Liu, Feng Liu
Publikováno v:
American journal of physiology. Endocrinology and metabolism. 296(5)
Calorie restriction (CR) alleviates insulin resistance and has a beneficial effect on numerous metabolic disorders, yet the underlying mechanism has not been fully elucidated. In the present study, we found that CR of mice (60% of the diet consumptio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02eca6d91a504ca9be91cb90158b616b
https://pubmed.ncbi.nlm.nih.gov/19240254
https://pubmed.ncbi.nlm.nih.gov/19240254
Publikováno v:
Autophagy. 9:108-109
A-type lamins, generated from the LMNA gene by differential splicing, are type V intermediate filament proteins that polymerize to form part of the nuclear lamina, and are of considerable medical interest because missense mutations in LMNA give rise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4ccf1d489639bff356fbd4da0d6f78e
https://doi.org/10.4161/auto.22401
https://doi.org/10.4161/auto.22401