Zobrazeno 1 - 10
of 171
pro vyhledávání: '"Fresia Pareja"'
Autor:
Chiu-Hsiang Connie Liao, Nilay Bakoglu, Emine Cesmecioglu, Matthew Hanna, Fresia Pareja, Hannah Y. Wen, Timothy M. D’Alfonso, Edi Brogi, Yukako Yagi, Dara S. Ross
Publikováno v:
Pathology and Oncology Research, Vol 30 (2024)
Human epidermal growth factor receptor 2 (HER2) gene amplification and subsequent protein overexpression is a strong prognostic and predictive biomarker in invasive breast carcinoma (IBC). ASCO/CAP recommended tests for HER2 assessment include immuno
Externí odkaz:
https://doaj.org/article/5ad66b7fe96047f1846f4c6e6e954da9
Autor:
Sushmita Gordhandas, Arnaud Da Cruz Paula, Elizabeth C. Kertowidjojo, Fresia Pareja, Kimberly Dessources, Edaise M. da Silva, Fatemeh Derakhshan, Jennifer J. Mueller, Nadeem R. Abu-Rustum, M. Herman Chui, Britta Weigelt
Publikováno v:
Gynecologic Oncology Reports, Vol 53, Iss , Pp 101391- (2024)
Externí odkaz:
https://doaj.org/article/8013523ea6fd4a99a7ed9434d3ad1847
Autor:
Higinio Dopeso, Andrea M. Gazzo, Fatemeh Derakhshan, David N. Brown, Pier Selenica, Sahar Jalali, Arnaud Da Cruz Paula, Antonio Marra, Edaise M. da Silva, Thais Basili, Laxmi Gusain, Lorraine Colon-Cartagena, Shirin Issa Bhaloo, Hunter Green, Chad Vanderbilt, Steffi Oesterreich, Anne Grabenstetter, M. Gabriela Kuba, Dara Ross, Dilip Giri, Hannah Y. Wen, Hong Zhang, Edi Brogi, Britta Weigelt, Fresia Pareja, Jorge S. Reis-Filho
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-11 (2024)
Abstract CDH1 (E-cadherin) bi-allelic inactivation is the hallmark alteration of breast invasive lobular carcinoma (ILC), resulting in its discohesive phenotype. A subset of ILCs, however, lack CDH1 genetic/epigenetic inactivation, and their genetic
Externí odkaz:
https://doaj.org/article/2bcd7e3ff5014c2e98a7bf5bd912578b
Autor:
Juan Blanco-Heredia, Carla Anjos Souza, Juan L. Trincado, Maria Gonzalez-Cao, Samuel Gonçalves-Ribeiro, Sara Ruiz Gil, Dmytro Pravdyvets, Samandhy Cedeño, Maurizio Callari, Antonio Marra, Andrea M. Gazzo, Britta Weigelt, Fresia Pareja, Theodore Vougiouklakis, Achim A. Jungbluth, Rafael Rosell, Christian Brander, Francesc Tresserra, Jorge S. Reis-Filho, Daniel Guimarães Tiezzi, Nuria de la Iglesia, Holger Heyn, Leticia De Mattos-Arruda
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract The interactions between tumor and immune cells along the course of breast cancer progression remain largely unknown. Here, we extensively characterize multiple sequential and parallel multiregion tumor and blood specimens of an index patien
Externí odkaz:
https://doaj.org/article/14cae652f3b14f88b2b7c2b80f375b63
Autor:
Jing Yu, Edaise M. da Silva, Hae-Sun La, Beth Z. Clark, Jeffrey L. Fine, Gloria J. Carter, Tatiana M. Villatoro, T. Rinda Soong, Adrian V. Lee, Steffi Oesterreich, Thais Basili, Juan Blanco-Heredia, Pier Selenica, Qiqi Ye, Arnaud Da Cruz Paula, Higinio Dopeso, Andrea Gazzo, Antonio Marra, Fresia Pareja, Jorge S. Reis-Filho, Rohit Bhargava
Publikováno v:
npj Breast Cancer, Vol 9, Iss 1, Pp 1-13 (2023)
Abstract This study describes “lobular-like invasive mammary carcinomas” (LLIMCas), a group of low- to intermediate-grade invasive mammary carcinomas with discohesive, diffusely infiltrative cells showing retained circumferential membranous immun
Externí odkaz:
https://doaj.org/article/a2ffe8ff28f6494d9753ae713d6f5f51
Autor:
Antonio Strillacci, Pasquale Sansone, Vinagolu K. Rajasekhar, Mesruh Turkekul, Vitaly Boyko, Fanli Meng, Brian Houck-Loomis, David Brown, Michael F. Berger, Ronald C. Hendrickson, Qing Chang, Elisa de Stanchina, Fresia Pareja, Jorge S. Reis-Filho, Ramya Segu Rajappachetty, Isabella Del Priore, Bo Liu, Yanyan Cai, Alex Penson, Chiara Mastroleo, Marjan Berishaj, Francesca Borsetti, Enzo Spisni, David Lyden, Sarat Chandarlapaty, Jacqueline Bromberg
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-16 (2022)
Abstract Estrogen receptor alpha (ERα) drives mammary gland development and breast cancer (BC) growth through an evolutionarily conserved linkage of DNA binding and hormone activation functions. Therapeutic targeting of the hormone binding pocket is
Externí odkaz:
https://doaj.org/article/f78ea24d939745a8868b8fcd4d4bff37
Autor:
Ivan J. Cohen, Fresia Pareja, Nicholas D. Socci, Ronglai Shen, Ashley S. Doane, Jazmin Schwartz, Raya Khanin, Elizabeth A. Morris, Elizabeth J. Sutton, Ronald G. Blasberg
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Response to immunotherapy across multiple cancer types is approximately 25%, with some tumor types showing increased response rates compared to others (i.e. response rates in melanoma and non-small cell lung cancer (NSCLC) are typically 30-60%). Pati
Externí odkaz:
https://doaj.org/article/b6d4c2779f6e4c78b8dc4b87286d952c
Autor:
Bastien Nguyen, Francisco Sanchez-Vega, Christopher J. Fong, Walid K. Chatila, Amir Momeni Boroujeni, Fresia Pareja, Britta Weigelt, Christos Sotiriou, Denis Larsimont, Jorge S. Reis-Filho, Christine Desmedt, Nikolaus Schultz
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract Mucinous carcinomas can arise in any organ with epithelial cells that produce mucus. While mucinous tumors from different organs are histologically similar, it remains to be elucidated whether they share molecular alterations. Here we analyz
Externí odkaz:
https://doaj.org/article/c0bc9dd2f7f64c679e8a4095f00c5414
Autor:
Lea A. Moukarzel, Lorenzo Ferrando, Arnaud Da Cruz Paula, David N. Brown, Felipe C. Geyer, Fresia Pareja, Salvatore Piscuoglio, Anastasios D. Papanastasiou, Nicola Fusco, Caterina Marchiò, Nadeem R. Abu‐Rustum, Rajmohan Murali, Edi Brogi, Hannah Y. Wen, Larry Norton, Robert A. Soslow, Anne Vincent‐Salomon, Jorge S. Reis‐Filho, Britta Weigelt
Publikováno v:
Molecular Oncology, Vol 15, Iss 4, Pp 1024-1039 (2021)
Metaplastic breast carcinoma (MBC) and uterine carcinosarcoma (UCS) are rare aggressive cancers, characterized by an admixture of adenocarcinoma and areas displaying mesenchymal/sarcomatoid differentiation. We sought to define whether MBCs and UCSs h
Externí odkaz:
https://doaj.org/article/d43d7492291245088deab363a8092b63
Autor:
Edaise M. da Silva, Pier Selenica, Mahsa Vahdatinia, Fresia Pareja, Arnaud Da Cruz Paula, Lorenzo Ferrando, Andrea M. Gazzo, Higinio Dopeso, Dara S. Ross, Ariya Bakhteri, Nadeem Riaz, Sarat Chandarlapaty, Pedram Razavi, Larry Norton, Hannah Y. Wen, Edi Brogi, Britta Weigelt, Hong Zhang, Jorge S. Reis-Filho
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-8 (2021)
Abstract Metaplastic breast cancers (MBCs) are characterized by complex genomes, which seem to vary according to their histologic subtype. TERT promoter hotspot mutations and gene amplification are rare in common forms of breast cancer, but present i
Externí odkaz:
https://doaj.org/article/f132c81e88b1476593e2db603427ca32