Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Freja Albjerg Venning"'
Autor:
Freja Albjerg Venning, Kamilla Westarp Zornhagen, Lena Wullkopf, Jonas Sjölund, Carmen Rodriguez-Cupello, Pontus Kjellman, Mikkel Morsing, Morteza Chalabi Hajkarim, Kyoung Jae Won, Janine Terra Erler, Chris Denis Madsen
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-21 (2021)
Abstract Background Cancer-associated fibroblasts (CAFs) comprise a heterogeneous population of stromal cells within the tumour microenvironment. CAFs exhibit both tumour-promoting and tumour-suppressing functions, making them exciting targets for im
Externí odkaz:
https://doaj.org/article/a5982df9dfdb4c37a2ed3833290a7ddd
Publikováno v:
Frontiers in Oncology, Vol 5 (2015)
Metastatic complications are responsible for more than 90% of cancer related deaths. The progression from an isolated tumor to disseminated metastatic disease is a multi-step process, with each step involving intricate cross-talk between the cancer c
Externí odkaz:
https://doaj.org/article/1f56d21dce5145a7ab070bfd74d0b995
Autor:
Kamilla Westarp Zornhagen, Chris D. Madsen, Kyoung-Jae Won, Lena Wullkopf, Freja Albjerg Venning, Morteza Chalabi Hajkarim, Janine Tera Erler
Cancer-associated fibroblasts (CAFs) comprise a heterogeneous population of stromal cells within the tumour microenvironment. CAFs exhibit both tumour-promoting and tumour-suppressing functions, making them exciting targets for improving cancer treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19077d2bf39af35d18bcb89ff471032a
https://doi.org/10.1101/2020.05.05.070607
https://doi.org/10.1101/2020.05.05.070607
Autor:
Chris D. Madsen, Edward R. Horton, Janine T. Erler, Alejandro E Mayorca-Guiliani, Thomas R. Cox, Freja Albjerg Venning
Publikováno v:
Nature Medicine
The extracellular matrix (ECM) is a master regulator of cellular phenotype and behavior. It has a crucial role in both normal tissue homeostasis and disease pathology. Here we present a fast and efficient approach to enhance the study of ECM composit
Hypoxia and loss of PHD 2 inactivate stromal fibroblasts to decrease tumour stiffness and metastasis
Autor:
Emad Moeendarbary, Freja Albjerg Venning, Thomas R. Cox, Chris D. Madsen, Jesper Torbøl Pedersen, Lukram Babloo Singh, Guillaume Charras, Erik Sahai, Janine T. Erler
Publikováno v:
EMBO Reports
Cancer‐associated fibroblasts (CAFs) interact with tumour cells and promote growth and metastasis. Here, we show that CAF activation is reversible: chronic hypoxia deactivates CAFs, resulting in the loss of contractile force, reduced remodelling of
Autor:
Freja Albjerg Venning, Esben Gjerløff Wedebye Schmidt, Mogens H. Claesson, Mette Louise Trempenau
Publikováno v:
APMIS. 122:616-627
Studies reporting beneficial effects of B lymphocytes in autoimmune diseases have been accumulating and a regulatory role for certain B cell subsets is hence getting more and more recognition. Recently, B cells were shown to exhibit a regulatory effe
Publikováno v:
Frontiers in Oncology
Metastatic complications are responsible for more than 90% of cancer-related deaths. The progression from an isolated tumor to disseminated metastatic disease is a multistep process, with each step involving intricate cross talk between the cancer ce
Publikováno v:
Journal of Cancer Science & Therapy.
Severe combined immunodeficiency (SCID) mice transplanted with CD4+ T cells depleted of CD25+ regulatory T cells develop colitis within 2-3 weeks after the T cell transfer. In the present study we studied the effect of the carcinogen azoxymethane (AO