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pro vyhledávání: '"Freitas, Rafaela Paula de"'
Autor:
Freitas, Rafaela Paula de
Anteriormente, foi identificada a atividade esquistossomicida da piplartina, um alcalóide-amida isolado em nossos estudos de bioprospecção em plantas da família Piperaceae. Neste trabalho, foi analisada a estrutura e as propriedades de uma série
Autor:
Lobo-Silva, Jessica, Cabral, Fernanda J., Murilo S. Amaral, Miyasato, Patrícia A., Freitas, Rafaela Paula De, Pereira, Adriana S. A., Khouri, Mariana I., Barbosa, Mayra M. F., Ramos, Pablo I. P., Leite, Luciana C. C., Oluwatoyin A. Asojo, Nakano, Eliana, Verjovski-Almeida, Sergio, Farias, Leonardo P.
Additional file 4: Figure S4. Decrease in egg size and oviposition in S. mansoni couples exposed to GSK-J4 and GSK-J5 for 72 h. Data are expressed as mean ± SEM from one experiment, data for 30 µM GSK-J5 point was replotted from the previous assay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c18b29148ac65211edc16957da18d995
Autor:
Lobo-Silva, Jessica, Cabral, Fernanda J., Murilo S. Amaral, Miyasato, Patrícia A., Freitas, Rafaela Paula De, Pereira, Adriana S. A., Khouri, Mariana I., Barbosa, Mayra M. F., Ramos, Pablo I. P., Leite, Luciana C. C., Oluwatoyin A. Asojo, Nakano, Eliana, Verjovski-Almeida, Sergio, Farias, Leonardo P.
Additional file 8: Figure S7. Confocal micrographs of muscle fibers of Schistosoma mansoni adult worms exposed to GSK-J4 7.5 μM for 24 h. Male and female worms stained with phalloidin-FITC revealing that muscle fibers lose their original features af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6b7f16d043760baabbccbff264282cf
Autor:
Lobo-Silva, Jessica, Cabral, Fernanda J., Murilo S. Amaral, Miyasato, Patrícia A., Freitas, Rafaela Paula De, Pereira, Adriana S. A., Khouri, Mariana I., Barbosa, Mayra M. F., Ramos, Pablo I. P., Leite, Luciana C. C., Oluwatoyin A. Asojo, Nakano, Eliana, Verjovski-Almeida, Sergio, Farias, Leonardo P.
Additional file 6: Figure S5. Confocal micrographs of Schistosoma mansoni adult worms exposed to GSK-J4 or GSK-J5.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfad3acb9cfeec90b0116161a921448c
Autor:
Lobo-Silva, Jessica, Cabral, Fernanda J., Murilo S. Amaral, Miyasato, Patrícia A., Freitas, Rafaela Paula De, Pereira, Adriana S. A., Khouri, Mariana I., Barbosa, Mayra M. F., Ramos, Pablo I. P., Leite, Luciana C. C., Oluwatoyin A. Asojo, Nakano, Eliana, Verjovski-Almeida, Sergio, Farias, Leonardo P.
Additional file 3: Figure S3. Comparison between the catalytic domain of the Schistosoma UTX protein sequence and human UTX/KDM6A, UTY and JMJD3/KDM6B. Alignments were generated by ClustalX. Residues involved in histone binding (red stars) and residu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ca3b821f93b4726e0b8038675c57a0f
Autor:
Lobo-Silva, Jessica, Cabral, Fernanda J., Murilo S. Amaral, Miyasato, Patrícia A., Freitas, Rafaela Paula De, Pereira, Adriana S. A., Khouri, Mariana I., Barbosa, Mayra M. F., Ramos, Pablo I. P., Leite, Luciana C. C., Oluwatoyin A. Asojo, Nakano, Eliana, Verjovski-Almeida, Sergio, Farias, Leonardo P.
Additional file 7: Figure S6. Confocal micrographs of the reproductive organs of Schistosoma mansoni female adult worms exposed to GSK-J4 or GSK-J5. Panel a was adapted from [50].
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45f6648306af390e9dae72328e9fecef
Autor:
Lobo-Silva, Jessica, Cabral, Fernanda J., Murilo S. Amaral, Miyasato, Patrícia A., Freitas, Rafaela Paula De, Pereira, Adriana S. A., Khouri, Mariana I., Barbosa, Mayra M. F., Ramos, Pablo I. P., Leite, Luciana C. C., Oluwatoyin A. Asojo, Nakano, Eliana, Verjovski-Almeida, Sergio, Farias, Leonardo P.
Additional file 1: Figure S1. Comparison of S. mansoni demethylase domain architecture and corresponding human orthologs. Proteins domains were mapped using SMART. This analysis includes only S. mansoni proteins presenting druggability score > 0.8.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3eea64db279deb8f5c1b0f2498973a7