Výsledky vyhledávání - "Freitas, Rafaela Paula"

Dissertation/ Thesis

Avaliação da atividade esquistossomicida de análogos sintéticos da piplartina em vermes adultos de Schistosoma mansoni.

Anteriormente, foi identificada a atividade esquistossomicida da piplartina, um alcalóide-amida isolado em nossos estudos de bioprospecção em plantas da família Piperaceae. Neste trabalho, foi analisada a estrutura e as propriedades de uma série

Externí odkaz: http://www.teses.usp.br/teses/disponiveis/87/87131/tde-31082015-150317/

Zobrazit plný text záznamu

Dissertation/ Thesis

Competência informacional e recursos informacionais na prática docente

Autor: Freitas, Rafaela Paula

Publikováno v: Repositório Institucional da UFSCUniversidade Federal de Santa CatarinaUFSC.

Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Educação, Programa de Pós-Graduação em Ciência da Informação, Florianópolis, 2010
Made available in DSpace on 2012-10-25T11:17:42Z (GMT). No. of b

Externí odkaz: http://repositorio.ufsc.br/xmlui/handle/123456789/94515

Zobrazit plný text záznamu

Additional file 4 of The antischistosomal potential of GSK-J4, an H3K27 demethylase inhibitor: insights from molecular modeling, transcriptomics and in vitro assays

Autor: Lobo-Silva, Jessica, Cabral, Fernanda J., Murilo S. Amaral, Miyasato, Patrícia A., Freitas, Rafaela Paula De, Pereira, Adriana S. A., Khouri, Mariana I., Barbosa, Mayra M. F., Ramos, Pablo I. P., Leite, Luciana C. C., Oluwatoyin A. Asojo, Nakano, Eliana, Verjovski-Almeida, Sergio, Farias, Leonardo P.

Additional file 4: Figure S4. Decrease in egg size and oviposition in S. mansoni couples exposed to GSK-J4 and GSK-J5 for 72 h. Data are expressed as mean ± SEM from one experiment, data for 30 µM GSK-J5 point was replotted from the previous assay

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c18b29148ac65211edc16957da18d995

Zobrazit plný text záznamu

Additional file 8 of The antischistosomal potential of GSK-J4, an H3K27 demethylase inhibitor: insights from molecular modeling, transcriptomics and in vitro assays

Additional file 8: Figure S7. Confocal micrographs of muscle fibers of Schistosoma mansoni adult worms exposed to GSK-J4 7.5 μM for 24 h. Male and female worms stained with phalloidin-FITC revealing that muscle fibers lose their original features af

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6b7f16d043760baabbccbff264282cf

Zobrazit plný text záznamu

Additional file 6 of The antischistosomal potential of GSK-J4, an H3K27 demethylase inhibitor: insights from molecular modeling, transcriptomics and in vitro assays

Additional file 6: Figure S5. Confocal micrographs of Schistosoma mansoni adult worms exposed to GSK-J4 or GSK-J5.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfad3acb9cfeec90b0116161a921448c

Zobrazit plný text záznamu

Additional file 3 of The antischistosomal potential of GSK-J4, an H3K27 demethylase inhibitor: insights from molecular modeling, transcriptomics and in vitro assays

Additional file 3: Figure S3. Comparison between the catalytic domain of the Schistosoma UTX protein sequence and human UTX/KDM6A, UTY and JMJD3/KDM6B. Alignments were generated by ClustalX. Residues involved in histone binding (red stars) and residu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ca3b821f93b4726e0b8038675c57a0f

Zobrazit plný text záznamu

Additional file 7 of The antischistosomal potential of GSK-J4, an H3K27 demethylase inhibitor: insights from molecular modeling, transcriptomics and in vitro assays

Additional file 7: Figure S6. Confocal micrographs of the reproductive organs of Schistosoma mansoni female adult worms exposed to GSK-J4 or GSK-J5. Panel a was adapted from [50].

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45f6648306af390e9dae72328e9fecef

Zobrazit plný text záznamu

Additional file 1 of The antischistosomal potential of GSK-J4, an H3K27 demethylase inhibitor: insights from molecular modeling, transcriptomics and in vitro assays

Additional file 1: Figure S1. Comparison of S. mansoni demethylase domain architecture and corresponding human orthologs. Proteins domains were mapped using SMART. This analysis includes only S. mansoni proteins presenting druggability score > 0.8.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3eea64db279deb8f5c1b0f2498973a7

Zobrazit plný text záznamu

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Vyhledávací nástroje:

Upřesnit hledání