Peripheral Tumor Necrosis Factor Production Is a Predictor for Remission Under Adalimumab in Crohn’s Disease

Autor: Freise, I., Staudacher, J.J., Haag, L.M., Kredel, L., Schumann, M., Weidinger, C., Sonnenberg, E., Jessen, Bosse, Tordai, Marcell T., Siegmund, Britta

Publikováno v: In Clinical Gastroenterology and Hepatology

Level of Tumor Necrosis Factor Production by Stimulated Blood Mononuclear Cells Can Be Used to Predict Response of Patients With Inflammatory Bowel Diseases to Infliximab.

Autor: Jessen B; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Campus Benjamin Franklin, Department for Medicine (Gastroenterology, Infectious diseases, Rheumatology), Berlin, Germany; Berlin Institute of Health (BIH), Berlin, Germany. Electronic address: bosse.jessen@charite.de., Rodriguez-Sillke Y; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Campus Benjamin Franklin, Department for Medicine (Gastroenterology, Infectious diseases, Rheumatology), Berlin, Germany., Sonnenberg E; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Campus Benjamin Franklin, Department for Medicine (Gastroenterology, Infectious diseases, Rheumatology), Berlin, Germany., Schumann M; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Campus Benjamin Franklin, Department for Medicine (Gastroenterology, Infectious diseases, Rheumatology), Berlin, Germany., Kruglov A; German Rheumatism Research Center (DRFZ), A Leibniz Institute, Berlin, Germany., Freise I; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Campus Benjamin Franklin, Department for Medicine (Gastroenterology, Infectious diseases, Rheumatology), Berlin, Germany., Schmidt F; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Campus Benjamin Franklin, Department for Medicine (Gastroenterology, Infectious diseases, Rheumatology), Berlin, Germany., Maul J; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Campus Benjamin Franklin, Department for Medicine (Gastroenterology, Infectious diseases, Rheumatology), Berlin, Germany; Gastroenterologie am Bayerischen Platz, Berlin, Germany., Kühl AA; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Campus Benjamin Franklin, iPATH.Berlin-Core Unit, Berlin, Germany., Glauben R; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Campus Benjamin Franklin, Department for Medicine (Gastroenterology, Infectious diseases, Rheumatology), Berlin, Germany., Lissner D; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Campus Benjamin Franklin, Department for Medicine (Gastroenterology, Infectious diseases, Rheumatology), Berlin, Germany., Siegmund B; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Campus Benjamin Franklin, Department for Medicine (Gastroenterology, Infectious diseases, Rheumatology), Berlin, Germany.

Publikováno v: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association [Clin Gastroenterol Hepatol] 2021 Apr; Vol. 19 (4), pp. 721-731.e1. Date of Electronic Publication: 2020 Apr 06.

Leptin induces TNFα-dependent inflammation in acquired generalized lipodystrophy and combined Crohn's disease.

Autor: Ziegler JF; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.; Department of Gastroenterology, Infectious Diseases and Rheumatology, Campus Benjamin Franklin, Berlin, Germany., Böttcher C; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.; Laboratory of Molecular Psychiatry and Department of Neuropsychiatry, Berlin, Germany., Letizia M; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.; Department of Gastroenterology, Infectious Diseases and Rheumatology, Campus Benjamin Franklin, Berlin, Germany., Yerinde C; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.; Department of Gastroenterology, Infectious Diseases and Rheumatology, Campus Benjamin Franklin, Berlin, Germany., Wu H; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.; Department of Gastroenterology, Infectious Diseases and Rheumatology, Campus Benjamin Franklin, Berlin, Germany., Freise I; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.; Department of Gastroenterology, Infectious Diseases and Rheumatology, Campus Benjamin Franklin, Berlin, Germany., Rodriguez-Sillke Y; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.; Department of Gastroenterology, Infectious Diseases and Rheumatology, Campus Benjamin Franklin, Berlin, Germany., Stoyanova AK; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.; Department of Visceral Surgery, Campus Benjamin Franklin, Berlin, Germany., Kreis ME; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.; Department of Visceral Surgery, Campus Benjamin Franklin, Berlin, Germany., Asbach P; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.; Department of Radiology, Campus Benjamin Franklin, Berlin, Germany., Kunkel D; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.; BIH Cytometry Core, Berlin Institute of Health, 10178, Berlin, Germany., Priller J; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.; Laboratory of Molecular Psychiatry and Department of Neuropsychiatry, Berlin, Germany.; BIH Berlin, DZNE Berlin and University of Edinburgh and UK DRI, Edinburgh, UK., Anagnostopoulos I; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.; Department of Pathology, Campus Charité Mitte, Berlin, Germany., Kühl AA; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.; iPATH.Berlin-Immunopathology for Experimental Models, Core Facility of the Charité, Berlin, Germany., Miehle K; Medical Department III-Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center, Leipzig, Germany., Stumvoll M; Medical Department III-Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center, Leipzig, Germany., Tran F; Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany., Fredrich B; Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany., Forster M; Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany., Franke A; Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany., Bojarski C; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.; Department of Gastroenterology, Infectious Diseases and Rheumatology, Campus Benjamin Franklin, Berlin, Germany., Glauben R; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.; Department of Gastroenterology, Infectious Diseases and Rheumatology, Campus Benjamin Franklin, Berlin, Germany., Löscher BS; Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany., Siegmund B; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany. britta.siegmund@charite.de.; Department of Gastroenterology, Infectious Diseases and Rheumatology, Campus Benjamin Franklin, Berlin, Germany. britta.siegmund@charite.de., Weidinger C; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany. carl.weidinger@charite.de.; Department of Gastroenterology, Infectious Diseases and Rheumatology, Campus Benjamin Franklin, Berlin, Germany. carl.weidinger@charite.de.; Clinician Scientist Program, Berlin Institute of Health, Berlin, Germany. carl.weidinger@charite.de.

Publikováno v: Nature communications [Nat Commun] 2019 Dec 10; Vol. 10 (1), pp. 5629. Date of Electronic Publication: 2019 Dec 10.

Genetically predicted metabolites mediate the causal associations between autoimmune thyroiditis and immune cells.

Autor: Yongzhao Chen, Bo Jiang, Cheng Qu, Chaoyu Jiang, Chen Zhang, Yanxue Wang, Fei Chen, Xitai Sun, Lei Su, Yuqian Luo

Publikováno v: Frontiers in Endocrinology; 2024, p01-13, 13p

Obesity and Risk for Lymphoma: Possible Role of Leptin.

Autor: Jiménez-Cortegana, Carlos^1,2,3 (AUTHOR), Hontecillas-Prieto, Lourdes^1,3 (AUTHOR), García-Domínguez, Daniel J.^1,3 (AUTHOR), Zapata, Fernando³ (AUTHOR), Palazón-Carrión, Natalia³ (AUTHOR), Sánchez-León, María L.³ (AUTHOR), Tami, Malika^1,3 (AUTHOR), Pérez-Pérez, Antonio¹ (AUTHOR), Sánchez-Jiménez, Flora¹ (AUTHOR), Vilariño-García, Teresa¹ (AUTHOR), de la Cruz-Merino, Luis³ (AUTHOR) luis.cruz.sspa@juntadeandalucia.es, Sánchez-Margalet, Víctor¹ (AUTHOR) luis.cruz.sspa@juntadeandalucia.es

Publikováno v: International Journal of Molecular Sciences. Dec2022, Vol. 23 Issue 24, p15530. 21p.