Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Freidrich M. Cruz"'
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(42)
MHC molecules are not randomly distributed on the plasma membrane but instead are present in discrete nanoclusters. The mechanisms that control formation of MHC I nanoclusters and the importance of such structures are incompletely understood. Here, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2874d1836ef5195201397213ded8d59d
https://pubmed.ncbi.nlm.nih.gov/36215490
https://pubmed.ncbi.nlm.nih.gov/36215490
Publikováno v:
Seminars in Immunology. 66:101729
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e640af40dfa080a0737407242a6ad2c2
https://doi.org/10.1016/j.smim.2023.101729
https://doi.org/10.1016/j.smim.2023.101729
Publikováno v:
Curr Opin Immunol
In order to get recognized by CD8 T cells, most cells present peptides from endogenously expressed self or foreign proteins on MHC class I molecules. However, specialized antigen-presenting cells, such as DCs and macrophages, can present exogenous an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3d3ac5c2ceb0d3a824cc52994aadd61
https://doi.org/10.1016/j.coi.2019.12.005
https://doi.org/10.1016/j.coi.2019.12.005
Publikováno v:
EMBO J
For CD8 T lymphocytes to mount responses to cancer and virally-infected cells, dendritic cells must capture antigens present in tissues and display them as peptides bound to MHC-I molecules. This is most often accomplished through a pathway called an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bff21141f802d61af7ea58cfd733375a
https://europepmc.org/articles/PMC6960445/
https://europepmc.org/articles/PMC6960445/
The Biology and Underlying Mechanisms of Cross-Presentation of Exogenous Antigens on MHC-I Molecules
Publikováno v:
Annual Review of Immunology. 35:149-176
To monitor the health of cells, the immune system tasks antigen-presenting cells with gathering antigens from other cells and bringing them to CD8 T cells in the form of peptides bound to MHC-I molecules. Most cells would be unable to perform this fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f80e0e5b8bb0a75dc094fcc392c2665
https://doi.org/10.1146/annurev-immunol-041015-055254
https://doi.org/10.1146/annurev-immunol-041015-055254
Publikováno v:
Immunity
The immune system monitors the health of cells and is stimulated by necrosis. Here we examined the receptors and ligands driving this response. In a targeted screen of C-type lectin receptors, a Clec2d reporter responded to lysates from necrotic cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c56b44f35e7ccf60bdb8dc61fcb13eb3
https://pubmed.ncbi.nlm.nih.gov/31951550
https://pubmed.ncbi.nlm.nih.gov/31951550
Autor:
Barry A. Kriegsman, Freidrich M. Cruz, Elena Merino-Rodriguez, Janice BelleIsle, Kenneth L. Rock
Publikováno v:
The Journal of Immunology. 200:99.2-99.2
Antigen presentation is the process by which cells generate and display peptides on major histocompatibility complex (MHC) molecules for T cell recognition. Although it is well known that antigen presentation is critical for effective adaptive immuni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7356c6407324eae35165d301ff4d620
https://doi.org/10.4049/jimmunol.200.supp.99.2
https://doi.org/10.4049/jimmunol.200.supp.99.2
Publikováno v:
Molecular Immunology. 51:25-26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53413b6e1d0479ff2432c3f85ae7c376
https://doi.org/10.1016/j.molimm.2012.02.068
https://doi.org/10.1016/j.molimm.2012.02.068