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of 271
pro vyhledávání: '"Freemont PS"'
Publikováno v:
Metabolic Engineering. 38:370-381
Cell-free transcription-translation systems were originally applied towards in vitro protein production. More recently, synthetic biology is enabling these systems to be used within a systematic design context for prototyping DNA regulatory elements,
Autor:
MacDonald, J, Freemont, PS
Publikováno v:
Biochemical Society Transactions
The computational algorithms used in the design of artificial proteins have become increasingly sophisticated in recent years, producing a series of remarkable successes. The most dramatic of these is the de novo design of artificial enzymes. The maj
Autor:
Hillson, N, Caddick, M, Cai, Y, Carrasco, JA, Chang, MW, Curach, NC, Bell, DJ, Le Feuvre, R, Friedman, DC, Fu, X, Gold, ND, Herrgard, MJ, Holowko, MB, Johnson, JR, Johnson, RA, Keasling, JD, Kitney, RI, Kondo, A, Liu, C, Martin, VJJ, Menolascina, F, Ogino, C, Patron, NJ, Pavan, M, Poh, CL, Pretorius, IS, Rosser, SJ, Scrutton, NS, Storch, M, Tekotte, H, Travnik, E, Vickers, CE, Yew, WS, Yuan, Y, Zhao, H, Freemont, PS
Publikováno v:
NATURE COMMUNICATIONS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::e3468b3ba1798a00e1cff16f28e3665e
Autor:
Wen, KY, Cameron, L, Chappell, J, Jensen, K, Bell, DJ, Kelwick, R, Kopniczky, M, Davies, JC, Filloux, A, Freemont, PS
Synthetic biology designed cell-free biosensors are a promising new tool for the detection of clinically relevant biomarkers in infectious diseases. Here, we report that a modular DNA-encoded biosensor in cell-free protein expression systems can be u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1032::0d5161415224a8613011d77088102e47
http://hdl.handle.net/10044/1/53616
http://hdl.handle.net/10044/1/53616
Many high-value added recombinant proteins, such as therapeutic glycoproteins, are produced using mammalian cell cultures. In order to optimise the productivity of these cultures it is important to monitor cellular metabolism, for example the utilisa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1032::ec7c7d1aea1f64e364db9b6bf3289a85
http://hdl.handle.net/10044/1/44165
http://hdl.handle.net/10044/1/44165
Publikováno v:
Molecular Microbiology
Molecular Microbiology, Wiley, 2012, 83 (5), pp.1064-1079. ⟨10.1111/j.1365-2958.2012.07989.x⟩
Molecular Microbiology, Wiley, 2012, 83 (5), pp.1064-1079. ⟨10.1111/j.1365-2958.2012.07989.x⟩
Although oxidative stress is a key aspect of innate immunity, little is known about how host-restricted pathogens successfully repair DNA damage. Base excision repair is responsible for correcting nucleobases damaged by oxidative stress, and is essen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1caa9b738328cfc825076f252136567f
https://hal.archives-ouvertes.fr/hal-03514331
https://hal.archives-ouvertes.fr/hal-03514331
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