Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Freek L. van Muiswinkel"'
Autor:
Peter Sodaar, Maria Stella Lombardi, Annemieke Kavelaars, Cobi Jacoba Johanna Heijnen, Freek L. Van Muiswinkel, Anne Vroon
Publikováno v:
Journal of Neurochemistry. 102:731-740
G protein-coupled receptor kinase 2 (GRK2) modulates G protein-coupled receptor desensitization and signaling. We previously described down-regulation of GRK2 expression in vivo in rat neonatal brain following hypoxia-ischemia. In this study, we inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe903929f1b2b4125261ebf33c14e8d7
https://doi.org/10.1111/j.1471-4159.2007.04576.x
https://doi.org/10.1111/j.1471-4159.2007.04576.x
Autor:
Benjamin Drukarch, Lars Bø, Jack van Horssen, Freek L. Van Muiswinkel, Lisette Montagne, Gerty Schreibelt, Helga E. de Vries
Publikováno v:
Free Radical Biology and Medicine, 41(2), 311-7. Elsevier Inc.
van Horssen, J, Schreibelt, G, Bö, L, Montagne, L, Drukarch, B, van Muiswinkel, F L & de Vries, H E 2006, ' NAD(P)H:quinone oxidoreductase 1 expression in multiple sclerosis lesions ', Free Radical Biology and Medicine, vol. 41, no. 2, pp. 311-7 . https://doi.org/10.1016/j.freeradbiomed.2006.04.013
van Horssen, J, Schreibelt, G, Bö, L, Montagne, L, Drukarch, B, van Muiswinkel, F L & de Vries, H E 2006, ' NAD(P)H:quinone oxidoreductase 1 expression in multiple sclerosis lesions ', Free Radical Biology and Medicine, vol. 41, no. 2, pp. 311-7 . https://doi.org/10.1016/j.freeradbiomed.2006.04.013
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS), marked by infiltration of monocyte-derived macrophages in the brain parenchyma. Macrophages contribute to disease pathology by secretion of inflammatory me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bc6e3e157f0993e90352624291748b8
https://doi.org/10.1016/j.freeradbiomed.2006.04.013
https://doi.org/10.1016/j.freeradbiomed.2006.04.013
Autor:
Freek L. van Muiswinkel, Gerry T. Snoek, Dop P. R. Bär, Peter Sodaar, Hanneke Bunte, Karel W. A. Wirtz, Martijn Schenning
Publikováno v:
Journal of Neurochemistry. 97:707-715
Selective neuronal loss is a prominent feature in both acute and chronic neurological disorders. Recently, a link between neurodegeneration and a deficiency in the lipid transport protein phosphatidylinositol transfer protein α (PI-TPα) has been de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7bc038390085e945371cf994781b7da
https://doi.org/10.1111/j.1471-4159.2006.03729.x
https://doi.org/10.1111/j.1471-4159.2006.03729.x
Autor:
Peter R. Bär, Liselijn A. B. Wisman, Pierre N. E. De Graan, Freek L. Van Muiswinkel, Elly M. Hol
Publikováno v:
NeuroReport. 14:1967-1970
Amyotrophic lateral sclerosis is an incurable disease in which cerebral and spinal motoneurons degenerate, causing paralysis and death within 2-5 years. One of the pathogenic factors of motoneuron death is a chronic excess of glutamate, which exceeds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f1d94ac1cb5044fadb253d8abcbaafd
https://doi.org/10.1097/00001756-200310270-00017
https://doi.org/10.1097/00001756-200310270-00017
Publikováno v:
Free Radical Research. 36:695-699
alpha-Lipoic acid (LA), an antioxidant with broad neuroprotective capacity, is thought to act by scavenging reactive oxygen species and stimulation of glutathione synthesis. LA shows structural resemblance to dithiolethiones, like anethole dithioleth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41584b0eefd2c29f021aa23acbfdd678
https://doi.org/10.1080/10715760290029155
https://doi.org/10.1080/10715760290029155
Autor:
Jan Verhoef, Hessel A. Smits, Hans S. L. M. Nottet, N. Machiel de Vos, Annemarie Rijsmus, Tjomme van der Bruggen, Astrid J. van Beelen, Freek L Van Muiswinkel
Publikováno v:
The Journal of Immunology. 166:6869-6876
In Alzheimer's disease, neuritic amyloid-beta plaques along with surrounding activated microglia and astrocytes are thought to play an important role in the inflammatory events leading to neurodegeneration. Studies have indicated that amyloid-beta ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1f5de4c3a04c445bb7a70df08cffb18
https://doi.org/10.4049/jimmunol.166.11.6869
https://doi.org/10.4049/jimmunol.166.11.6869
Publikováno v:
European Journal of Pharmacology. 230:349-355
The effects of selective opioid agonists on the evoked release of [3H]dopamine and [3H]noradrenaline were studied in cultured dopaminergic neurons of the ventral mesencephalon (containing the substantia nigra and ventral tegmental area) and in cultur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::764283f2dc618d1135b3103989cf8259
https://doi.org/10.1016/0014-2999(93)90572-y
https://doi.org/10.1016/0014-2999(93)90572-y
Autor:
Maria Stella, Lombardi, Anne, Vroon, Peter, Sodaar, Freek L, van Muiswinkel, Cobi J, Heijnen, Annemieke, Kavelaars
Publikováno v:
Journal of neurochemistry. 102(3)
G protein-coupled receptor kinase 2 (GRK2) modulates G protein-coupled receptor desensitization and signaling. We previously described down-regulation of GRK2 expression in vivo in rat neonatal brain following hypoxia-ischemia. In this study, we inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6ba2da99119895e9cc06c20be7203740
https://pubmed.ncbi.nlm.nih.gov/17437535
https://pubmed.ncbi.nlm.nih.gov/17437535
Autor:
John G.J.M. Bol, Freek L. Van Muiswinkel, Erik Ch. Wolters, Amie L. Phinney, Anne-Marie W. van Dam, Benjamin Drukarch, Gerda Andringa
Publikováno v:
Phinney, A L, Andringa, G, Bol, J G J M, Wolters, E C, van Muiswinkel, F L, van Dam, A-M W & Drukarch, B 2006, ' Enhanced sensitivity of dopaminergic neurons to rotenone-induced toxicity with aging ', Parkinsonism and Related Disorders, vol. 12, no. 4, pp. 228-38 . https://doi.org/10.1016/j.parkreldis.2005.12.002
Parkinsonism and Related Disorders, 12(4), 228-38. Elsevier BV
Parkinsonism and Related Disorders, 12(4), 228-38. Elsevier BV
Rotenone has been reported to induce various degrees of Parkinsonism in rats. We tested whether advancing age alters the sensitivity of dopaminergic neurons to rotenone. A low, systemic dose of rotenone had no effect on young rats, but led to a 20-30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::791aac535122f742ed126a12f85b406d
https://research.vumc.nl/en/publications/e964aa15-ea2a-47ef-9054-99f69a09f812
https://research.vumc.nl/en/publications/e964aa15-ea2a-47ef-9054-99f69a09f812
Autor:
Hanneke, Bunte, Martijn, Schenning, Peter, Sodaar, Dop P R, Bär, Karel W A, Wirtz, Freek L, van Muiswinkel, Gerry T, Snoek
Publikováno v:
Journal of neurochemistry. 97(3)
Selective neuronal loss is a prominent feature in both acute and chronic neurological disorders. Recently, a link between neurodegeneration and a deficiency in the lipid transport protein phosphatidylinositol transfer protein alpha (PI-TPalpha) has b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d1de37d66dfa4e3cc911a08a52aca2ad
https://pubmed.ncbi.nlm.nih.gov/16573656
https://pubmed.ncbi.nlm.nih.gov/16573656