Zobrazeno 1 - 10
of 215
pro vyhledávání: '"Freek J, Beekman"'
Autor:
Koen Willemsen, Mirte H. M. Ketel, Frank Zijlstra, Mateusz C. Florkow, Ruurd J. A. Kuiper, Bart C. H. van der Wal, Harrie Weinans, Behdad Pouran, Freek J. Beekman, Peter R. Seevinck, Ralph J. B. Sakkers
Publikováno v:
3D Printing in Medicine, Vol 7, Iss 1, Pp 1-12 (2021)
Abstract Background Three-dimensional (3D)-printed saw guides are frequently used to optimize osteotomy results and are usually designed based on computed tomography (CT), despite the radiation burden, as radiation-less alternatives like magnetic res
Externí odkaz:
https://doaj.org/article/5cecf2db19b849188182136c41b75229
Autor:
Lisanne de Vor, Bruce van Dijk, Kok van Kessel, Jeffrey S Kavanaugh, Carla de Haas, Piet C Aerts, Marco C Viveen, Edwin C Boel, Ad C Fluit, Jakub M Kwiecinski, Gerard C Krijger, Ruud M Ramakers, Freek J Beekman, Ekaterina Dadachova, Marnix GEH Lam, H Charles Vogely, Bart CH van der Wal, Jos AG van Strijp, Alexander R Horswill, Harrie Weinans, Suzan HM Rooijakkers
Publikováno v:
eLife, Vol 11 (2022)
Implant-associated Staphylococcus aureus infections are difficult to treat because of biofilm formation. Bacteria in a biofilm are often insensitive to antibiotics and host immunity. Monoclonal antibodies (mAbs) could provide an alternative approach
Externí odkaz:
https://doaj.org/article/f9dfe179409a4ffabf19a218bc324d32
Autor:
Bruce van Dijk, J. Fred F. Hooning van Duyvenbode, Lisanne de Vor, F. Ruben H. A. Nurmohamed, Marnix G. E. H. Lam, Alex J. Poot, Ruud M. Ramakers, Sofia Koustoulidou, Freek J. Beekman, Jos van Strijp, Suzan H. M. Rooijakkers, Ekaterina Dadachova, H. Charles Vogely, Harrie Weinans, Bart C. H. van der Wal
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 5, p 4374 (2023)
Implant infections caused by Staphylococcus aureus are difficult to treat due to biofilm formation, which complicates surgical and antibiotic treatment. We introduce an alternative approach using monoclonal antibodies (mAbs) targeting S. aureus and p
Externí odkaz:
https://doaj.org/article/36872d55e41c4eb5809cab4c0ec6568e
Autor:
Tuomas O. Lilius, Kristian Nygaard Mortensen, Claire Deville, Terhi J. Lohela, Frederik Filip Stæger, Björn Sigurdsson, Elisabetta M. Fiordaliso, Marko Rosenholm, Chris Kamphuis, Freek J. Beekman, Andreas I. Jensen, Maiken Nedergaard
Publikováno v:
Journal of Controlled Release: official journal of the Controlled Release Society, 355
Lilius, T O, Mortensen, K N, Deville, C, Lohela, T J, Stæger, F F, Sigurdsson, B, Fiordaliso, E M, Rosenholm, M, Kamphuis, C, Beekman, F J, Jensen, A I & Nedergaard, M 2023, ' Glymphatic-assisted perivascular brain delivery of intrathecal small gold nanoparticles ', Journal of controlled release, vol. 355, pp. 135-148 . https://doi.org/10.1016/j.jconrel.2023.01.054
Lilius, T O, Mortensen, K N, Deville, C, Lohela, T J, Stæger, F F, Sigurdsson, B, Fiordaliso, E M, Rosenholm, M, Kamphuis, C, Beekman, F J, Jensen, A I & Nedergaard, M 2023, ' Glymphatic-assisted perivascular brain delivery of intrathecal small gold nanoparticles ', Journal of controlled release, vol. 355, pp. 135-148 . https://doi.org/10.1016/j.jconrel.2023.01.054
Nanoparticles are ultrafine particulate matter having considerable potential for treatment of central nervous system (CNS) disorders. Despite their tiny size, the blood-brain barrier (BBB) restricts their access to the CNS. Their direct cerebrospinal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41d67831ba45105125ad18a25a7a7f0a
http://hdl.handle.net/10138/356330
http://hdl.handle.net/10138/356330
Publikováno v:
Physics in Medicine and Biology, 68(7)
Microscopic nuclear imaging down to spatial resolutions of a few hundred microns can already be achieved using low-energy gamma emitters (e.g. 125I, ∼30 keV) and a basic single micro-pinhole gamma camera. This has been applied to in vivo mouse thyr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d66eff3fcb32a9f79ea567586c1ca09
http://resolver.tudelft.nl/uuid:8e1a39cd-3ea7-49d9-95be-c8d3754f6e2a
http://resolver.tudelft.nl/uuid:8e1a39cd-3ea7-49d9-95be-c8d3754f6e2a
Publikováno v:
IEEE Transactions on Radiation and Plasma Medical Sciences, 4(1)
Photomultiplier tube (PMT)-based scintillation cameras are predominant in molecular imaging but have the drawback that position estimation is severely degraded near the edges (dead edge effect). This leads to sensitivity losses and can cause severe p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6453a94205516879d20d80893691a65
https://doi.org/10.1109/trpms.2019.2916386
https://doi.org/10.1109/trpms.2019.2916386
Autor:
Huanhuan Liu, Robin M. de Kruijff, Adrianus C. Laan, Freek J. Beekman, Eline van den Heuvel, Ruud M. Ramakers, Rienk Eelkema, Antonia G. Denkova
Publikováno v:
Advanced Therapeutics, 5(9)
A variety of polymer micelles are designed for the delivery of chemotherapeutic drugs to tumors. Although the promise of these nanocarriers is very high, in the clinic the effectivity is rather limited. Determining the in vivo fate of the micelles ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9d73f48bba30c8aaa12461df3209ff9
https://doi.org/10.1002/adtp.202200077
https://doi.org/10.1002/adtp.202200077
Autor:
Bruce van Dijk, Lisanne de Vor, Kok van Kessel, Jeffrey S Kavanaugh, Carla de Haas, Piet C Aerts, Marco C Viveen, Edwin C Boel, Ad C Fluit, Jakub M Kwiecinski, Gerard C Krijger, Ruud M Ramakers, Freek J Beekman, Ekaterina Dadachova, Marnix GEH Lam, H Charles Vogely, Bart CH van der Wal, Jos AG van Strijp, Alexander R Horswill, Harrie Weinans, Suzan HM Rooijakkers
Publikováno v:
eLife, Vol 11 (2022)
eLife, 11
eLife, 11
Implant-associated Staphylococcus aureus infections are difficult to treat because of biofilm formation. Bacteria in a biofilm are often insensitive to antibiotics and host immunity. Monoclonal antibodies (mAbs) could provide an alternative approach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ea975441d1c76989ff2bd8fedabb64b
https://ruj.uj.edu.pl/xmlui/handle/item/312334
https://ruj.uj.edu.pl/xmlui/handle/item/312334
Autor:
Bruce van Dijk, Lisanne de Vor, Kok van Kessel, Jeffrey S Kavanaugh, Carla de Haas, Piet C Aerts, Marco C Viveen, Edwin C Boel, Ad C Fluit, Jakub M Kwiecinski, Gerard C Krijger, Ruud M Ramakers, Freek J Beekman, Ekaterina Dadachova, Marnix GEH Lam, H Charles Vogely, Bart CH van der Wal, Jos AG van Strijp, Alexander R Horswill, Harrie Weinans, Suzan HM Rooijakkers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1316cdc5b545935f37ec8c01c08dbff
https://doi.org/10.7554/elife.67301.sa2
https://doi.org/10.7554/elife.67301.sa2
Autor:
Chao Wu, Pieter E.B. Vaissier, Brendan Vastenhouw, Johan R. de Jong, Riemer H.J.A. Slart, Freek J. Beekman
Publikováno v:
Molecular Imaging, Vol 14 (2015)
Cardiac parameters obtained from single-photon emission computed tomographic (SPECT) images can be affected by respiratory motion, image filtering, and animal positioning. We investigated the influence of these factors on ultra-high-resolution murine
Externí odkaz:
https://doaj.org/article/00e42b18281343eaa87481da0082820f