Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Freek G, Bouwman"'
Autor:
Rald V. M. Groven, Christel Kuik, Johannes Greven, Ümit Mert, Freek G. Bouwman, Martijn Poeze, Taco J. Blokhuis, Markus Huber-Lang, Frank Hildebrand, Berta Cillero-Pastor, Martijn van Griensven
Publikováno v:
Bone & Joint Research, Vol 13, Iss 5, Pp 214-225 (2024)
Aims: The aim of this study was to determine the fracture haematoma (fxH) proteome after multiple trauma using label-free proteomics, comparing two different fracture treatment strategies. Methods: A porcine multiple trauma model was used in which tw
Externí odkaz:
https://doaj.org/article/573a6f6a87ed43d9be6fe17da2e0373b
Autor:
Iris Cuijpers, Colin G. M. Dohmen, Freek G. Bouwman, Freddy J. Troost, Mireille M. J. P. E. Sthijns
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
IntroductionSkeletal muscle regeneration is impaired in elderly. An oxidative stress-induced decrease in differentiation capacity of muscle satellite cells is a key factor in this process. The aim of this study is to investigate whether orange polyph
Externí odkaz:
https://doaj.org/article/7a772c008fce459b9d3723e05bbbd5b8
Autor:
Joël E. J. Beaumont, Lydie M. O. Barbeau, Jinzhe Ju, Kim G. Savelkouls, Freek G. Bouwman, Marijke I. Zonneveld, Annelies Bronckaers, Kim R. Kampen, Tom G. H. Keulers, Kasper M. A. Rouschop
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 7, Pp n/a-n/a (2024)
Abstract Hypoxia is a common feature of solid tumours and activates adaptation mechanisms in cancer cells that induce therapy resistance and has profound effects on cellular metabolism. As such, hypoxia is an important contributor to cancer progressi
Externí odkaz:
https://doaj.org/article/ec4b00231fe04dc18ed39d6c447f3218
Autor:
Emanuel E. Canfora, Lars M. M. Vliex, Taojun Wang, Arjen Nauta, Freek G. Bouwman, Jens J. Holst, Koen Venema, Erwin G. Zoetendal, Ellen E. Blaak
Publikováno v:
Frontiers in Nutrition, Vol 10 (2023)
BackgroundInfusion of short-chain fatty acids (SCFA) to the distal colon beneficially affects human substrate and energy metabolism. Here, we hypothesized that the combination of 2′-fucosyllactose (2′-FL) with resistant starch (RS) increases dist
Externí odkaz:
https://doaj.org/article/fc60655e59c847819a7ef61882cbd547
Autor:
Thirza van Deuren, Lotte Smolders, Anita Hartog, Freek G. Bouwman, Jens J. Holst, Koen Venema, Ellen E. Blaak, Emanuel E. Canfora
Publikováno v:
Frontiers in Nutrition, Vol 9 (2023)
BackgroundShort chain fatty acids (SCFA) are increasingly recognized for their potential ability to alleviate obesity-associated chronic low-grade inflammation and disturbed energy homeostasis. Evidence suggests that an increase in circulating SCFA m
Externí odkaz:
https://doaj.org/article/0c3e7c73982b4f85b1b18915b4f74934
Autor:
M. Christella L.G.D. Thomassen, Bryan R.C. Bouwens, Kanin Wichapong, Dennis P. Suylen, Freek G. Bouwman, Tilman M. Hackeng, Rory R. Koenen
Publikováno v:
Journal of Thrombosis and Haemostasis, 21, 1214-1226. Wiley
Background: Tissue factor pathway inhibitor (TFPI) is an important regulator of coagulation and a link between inflammation and thrombosis. During thrombotic events, TFPI is proteolytically inactivated by neutrophil elastase while bound to neutrophil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::025d634a60b28c92bbc462064bf8305e
https://doi.org/10.1016/j.jtha.2023.01.017
https://doi.org/10.1016/j.jtha.2023.01.017
Autor:
Qi Qiao, Freek G. Bouwman, Marleen A. van Baak, Nadia J. T. Roumans, Roel G. Vink, Susan L. M. Coort, Johan W. Renes, Edwin C. M. Mariman
Publikováno v:
Adipocyte, Vol 8, Iss 1, Pp 190-200 (2019)
Long-term weight loss maintenance is a problem of overweight and obesity. Changes of gene expression during weight loss (WL) by calorie restriction (CR) are linked to the risk of weight regain (WR). However, detailed information on genes/proteins inv
Externí odkaz:
https://doaj.org/article/3227fb21dd4043de9b601f668f675ab8
Proteomic analysis reveals procoagulant properties of cigarette smoke-induced extracellular vesicles
Autor:
Birke J. Benedikter, Freek G. Bouwman, Alexandra C. A. Heinzmann, Tanja Vajen, Edwin C. Mariman, Emiel F. M. Wouters, Paul H. M. Savelkoul, Rory R. Koenen, Gernot G. U. Rohde, Rene van Oerle, Henri M. Spronk, Frank R. M. Stassen
Publikováno v:
Journal of Extracellular Vesicles, Vol 8, Iss 1 (2019)
Airway epithelial cells secrete extracellular vesicles (EVs) under basal conditions and when exposed to cigarette smoke extract (CSE). Getting insights into the composition of these EVs will help unravel their functions in homeostasis and smoking-ind
Externí odkaz:
https://doaj.org/article/2e10a0f1e43948209df9eeb2724a1d44
Autor:
Alexander S. Streng, Douwe de Boer, Freek G. Bouwman, Edwin C.M. Mariman, Arjen Scholten, Marja P. van Dieijen-Visser, Will K.W.H. Wodzig
Publikováno v:
Data in Brief, Vol 7, Iss , Pp 397-405 (2016)
Cardiac troponin T (cTnT) fragmentation in human serum was investigated using a newly developed targeted selected ion monitoring assay, as described in the accompanying article: “Development of a targeted selected ion monitoring assay for the eluci
Externí odkaz:
https://doaj.org/article/d5d095d3522e4e3ea38d0cb94fade487
Autor:
Berta Cillero-Pastor, Annelies Boonen, Ron M. A. Heeren, Maxime R. Eveque-Mourroux, Freek G. Bouwman, Pieter J. Emans, Britt S. R. Claes
Publikováno v:
Journal of Proteome Research, 20(5), 2973-2982. American Chemical Society
Journal of Proteome Research
Journal of Proteome Research
Osteoarthritis (OA) is a multifactorial pathology and comprises a wide range of distinct phenotypes. In this context, the characterization of the different molecular profiles associated with each phenotype can improve the classification of OA. In par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd71839e52c7c6a47a35869c2a79389f
https://cris.maastrichtuniversity.nl/en/publications/127777fe-5c90-4a66-a406-96706917bd19
https://cris.maastrichtuniversity.nl/en/publications/127777fe-5c90-4a66-a406-96706917bd19