Zobrazeno 1 - 10
of 1 722
pro vyhledávání: '"Free light chains"'
Autor:
Manlio Fazio, Chiara Maria Catena Sorbello, Vittorio Del Fabro, Alessandra Romano, Maria Teresa Cannizzaro, Nunziatina Laura Parrinello, Benedetta Esposito, Sara Frazzetto, Federica Elia, Francesco Di Raimondo, Concetta Conticello
Publikováno v:
Hematology Reports, Vol 16, Iss 3, Pp 541-551 (2024)
Neoplastic plasma cells (PCs) proliferation at anatomic sites dislocated from the bone marrow (BM) or their contiguous growth from osseous lesions that disrupt the cortical bone is termed extramedullary multiple myeloma (EMD). EMD still remains chall
Externí odkaz:
https://doaj.org/article/11046c4e4c2847b4bf27b2213c705ae2
Autor:
Patricia Kleinova, Timea Blichova, Monika Beliancinova, Matej Vnucak, Karol Granak, Ivana Dedinska
Publikováno v:
Acta Medica Martiniana, Vol 24, Iss 2, Pp 92-99 (2024)
As a heterogeneous group of diseases, monoclonal gammopathy is typical for older age and is characterized by the presence of paraprotein in serum and urine. In addition to damage to the bone marrow, other organs are also affected, whereas in the case
Externí odkaz:
https://doaj.org/article/e6eaf6fa4e074946ae35ca0fdf761e4f
Autor:
Sh. R. Nabiev, S. A. Dzhukkaeva, M. Sh. Asvedov, D. E. Prokhorov, E. V. Popova, V. V. Grinyuk, P. R. Magomadova, A. R. Apevalova, O. N. Voskresenskaya
Publikováno v:
Неврология, нейропсихиатрия, психосоматика, Vol 16, Iss 3, Pp 26-30 (2024)
Objective: to determine the sensitivity and specificity of method of determining the concentration of immunoglobulin free light chains (FLCs) in cerebrospinal fluid (CSF) in the diagnosis and differential diagnosis of multiple sclerosis (MS).Material
Externí odkaz:
https://doaj.org/article/5cd080d7bce04004852f43dac3e6aa02
Autor:
Hokhim Yau, Liye Zhong, Sheng Li, Weiting He, Yaxi Zhu, Pengjun Liao, Jianteng Xie, Hongwen Fei, Liwen Li, Hui Liu, Jie Li, Wenjian Wang
Publikováno v:
Medicine Advances, Vol 2, Iss 1, Pp 82-94 (2024)
Abstract Background The prognosis of patients with light‐chain amyloidosis (AL) has improved markedly in the past decade in China; whether the current staging systems are suitable to predict the overall survival (OS) of the patients remains undeter
Externí odkaz:
https://doaj.org/article/4dc6323376a14bf78925bc1e685c97b6
Autor:
Cathérine Dekeyser, Pieter De Kesel, Melissa Cambron, Ludo Vanopdenbosch, Liesbeth Van Hijfte, Martine Vercammen, Guy Laureys
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundCerebrospinal fluid (CSF) kappa free light chain (κFLC) measures gained increasing interest as diagnostic markers in multiple sclerosis (MS). However, the lack of studies comparing assay-dependent diagnostic cutoff values hinders their use
Externí odkaz:
https://doaj.org/article/0d37abcdf0564cd19a52a700c5b684c8
Autor:
Youyoung Kim, John P. Campbell, Neil M. Johannsen, Timothy S. Church, Eunhan Cho, Jennifer Heaney, Guillaume Spielmann
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Background and aims: Serum polyclonal free light chains (FLCs) levels are associated with overall survival in the general population, reflecting their utility as a biomarker of underlying immune activation and inflammation. Regular exercise is known
Externí odkaz:
https://doaj.org/article/236081f3d9d64ebb843c402fb3edfe6d
Publikováno v:
Neurología, Vol 38, Iss 9, Pp 663-670 (2023)
Resumen: Introducción: La mayoría de los pacientes con esclerosis múltiple (EM) debutan con un síndrome clínico aislado (SCA). Es importante diferenciar este SCA de otras patologías neurológicas agudas o subagudas y estimar el riesgo de desarr
Externí odkaz:
https://doaj.org/article/9e2869e4c76647d48ca828ed608499e1
Autor:
Felix Korell, Stefan Schönland, Anita Schmitt, Madelaine Jansen, Kiavasch Farid, Carsten Müller-Tidow, Peter Dreger, Michael Schmitt, Ute Hegenbart
Publikováno v:
Biomarker Research, Vol 11, Iss 1, Pp 1-5 (2023)
Abstract Light chain amyloidosis (AL) is a rare disease caused by the generalized deposition of misfolded free light chains. Patients with immunoglobulin M gammopathy (IgM) and indolent B-cell lymphoma such as marginal zone lymphoma (MZL) may in some
Externí odkaz:
https://doaj.org/article/13e1843c81ab4f838c20a79d797c1993
Plasma cell dyscrasia: monoclonal gammopathies, AL-amyloidosis, multiple myeloma Clinical case study
Publikováno v:
Онкогематология, Vol 18, Iss 1, Pp 57-62 (2023)
This study was performed in real clinical practice settings. Our paper describes two case studies which show the difficulty of differential diagnosis of monoclonal gammopathies, multiple myeloma associated with AL-amyloidosis and primary AL-amyloidos
Externí odkaz:
https://doaj.org/article/b45c94c1c91747dca3f00cd71e11820a
Autor:
A. A. Churko, A. Sh. Rumyantsev
Publikováno v:
Juvenis Scientia, Vol 9, Iss 3, Pp 42-50 (2023)
Introduction. Light chains of immunoglobulins are not only structural elements of immunoglobulins of all classes, but can become independent units of immuno-mediated inflammatory reactions. Serum polyclonal free light chains (pFLC) are also found i
Externí odkaz:
https://doaj.org/article/6b5f0a5667494c22826a3d4885c4a032