Zobrazeno 1 - 10
of 1 221
pro vyhledávání: '"Free Light Chain"'
Publikováno v:
Renal Failure, Vol 46, Iss 1 (2024)
Background Light-chain proximal tubulopathy (LCPT) is a rare disease characterized by the accumulation of monoclonal light chains within proximal tubular cells. This study aimed to investigate the clinical characteristics of LCPT from a single Chines
Externí odkaz:
https://doaj.org/article/66242db2c97049ccb428c4085ef9eee1
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-8 (2024)
Abstract Multiple myeloma (MM) denotes a cancerous growth characterized by abnormal proliferation of plasma cells. Growing evidence suggests that the complexity in addressing MM lies in the presence of minimal residual disease (MRD) within the body.
Externí odkaz:
https://doaj.org/article/738a5890f35448639e73d78c7f7f6e75
Autor:
Nitin J. Burkule
Publikováno v:
Journal of the Indian Academy of Echocardiography & Cardiovascular Imaging, Vol 8, Iss 1, Pp 17-32 (2024)
Cardiac amyloid cardiomyopathy (CM) is a rapidly progressive disease that is frequently underrecognized and frequently diagnosed late in a significant number of individuals suffering from heart failure. Cardiac amyloid infiltration resulting in myoca
Externí odkaz:
https://doaj.org/article/0a83ffc3a6c24e12bf48e1754cc814f2
Publikováno v:
Journal of Laboratory Physicians, Vol 15, Iss 04, Pp 518-523 (2023)
Introduction Serum immunofixation electrophoresis (SIFE) and serum free light chain (SFLC) assay are imperative investigations in diagnosis and follow-up of multiple myeloma (MM). SFLC assays are reported to have higher sensitivity than SIFE. However
Externí odkaz:
https://doaj.org/article/942899291c0445b3ba1fa3465ee8c2d2
Autor:
XIE Yaqiong, LIN Xiaoyi
Publikováno v:
Zhenduanxue lilun yu shijian, Vol 22, Iss 02, Pp 166-171 (2023)
Objective: To assess the diagnostic efficacy of serum free light chain (sFLC) levels in differential diagnosis of monoclonal gammopathies of renal significance, and to evaluate the correlation between sFLC and stages of kidney disease caused by vario
Externí odkaz:
https://doaj.org/article/1616046e2d364d52ab8f85584025a1a6
Publikováno v:
Zhenduanxue lilun yu shijian, Vol 22, Iss 02, Pp 172-177 (2023)
Objective: To explore whether the novel urine free light chain (uFLC) assay is superior to the traditional urine total light chain (uTLC) assay in quantitative monitoring of urine light chain. Methods: A total of 458 paired samples of blood and were
Externí odkaz:
https://doaj.org/article/e14666aa4c1c4fbb9d7e8255ba2219ea
Autor:
Harald Hegen, Klaus Berek, Paola Cavalla, Mikael Christiansen, Andreja Emeršič, Massimiliano Di Filippo, Lorenzo Gaetani, Michaela Hassler, Cyra Leurs, Dejan Milosavljevic, Vincent van Pesch, Thor Petersen, Stefan Presslauer, Igal Rosenstein, Uroš Rot, Christine Schnabl, Charlotte Teunissen, Domizia Vecchio, Marco Vercellino, Florian Deisenhammer
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundKappa free light chains (κ-FLC) in the cerebrospinal fluid (CSF) are an emerging biomarker in multiple sclerosis (MS).ObjectiveTo investigate whether κ-FLC index has similar diagnostic value in patients with primary progressive multiple s
Externí odkaz:
https://doaj.org/article/f2268023c7d1409780b691eaa832cee5
Autor:
Enric Monreal, José Ignacio Fernández-Velasco, Ana García-Soidán, Susana Sainz de la Maza, Mercedes Espiño, Noelia Villarrubia, Fernando Rodríguez-Jorge, Juan Luís Chico-García, Raquel Sainz-Amo, Jaime Masjuan, Lucienne Costa-Frossard, Luisa María Villar
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe immunoglobulin kappa free light chain (KFLC) index has been proposed as a potentially suitable alternative to oligoclonal IgG bands (OCGB) for diagnosing multiple sclerosis (MS), offering automation and reduced processing time. Howeve
Externí odkaz:
https://doaj.org/article/c856cfa855b74d99a369be3e14854d57
Publikováno v:
Renal Failure, Vol 44, Iss 1, Pp 1-10 (2022)
Objectives Increased polyclonal free light chains (FLCs) are found in inflammatory conditions. Inflammation is recognized in the progression of acute kidney injury (AKI). This study was aimed to determine whether polyclonal combined FLC (cFLC) was as
Externí odkaz:
https://doaj.org/article/5142409674254b9ca5493b02a2ab3238
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