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pro vyhledávání: '"Fredy Rojo"'
Autor:
Mónica García, José Baselga, Veeraswamy Manne, Carmen Garrido, Michael K. Cooper, Maurizio Voi, Fredy Rojo, James A. Manning, Sonia Valverde, Irene Marimón, Anne Van Vreckem, Joaquim Bellmunt, Josep Tabernero, Josep M. del Campo, Enriqueta Felip, Joan Albanell, Marta Guix, Jordi Andreu, Federico Vazquez, J Carulla
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 23(11)
Purpose BMS-214662 is a potent, nonpeptide, small molecule inhibitor of human farnesyltransferase (FT). We have conducted a phase I pharmacokinetic (PK) and pharmacodynamic study of BMS-214662 administered intravenously weekly with 1- and 24-hour inf