Vasculogenic mimicry in small cell lung cancer

Autor: Stuart C. Williamson, Robert L. Metcalf, Francesca Trapani, Sumitra Mohan, Jenny Antonello, Benjamin Abbott, Hui Sun Leong, Christopher P. E. Chester, Nicole Simms, Radoslaw Polanski, Daisuke Nonaka, Lynsey Priest, Alberto Fusi, Fredrika Carlsson, Anders Carlsson, Mary J. C. Hendrix, Richard E. B. Seftor, Elisabeth A. Seftor, Dominic G. Rothwell, Andrew Hughes, James Hicks, Crispin Miller, Peter Kuhn, Ged Brady, Kathryn L. Simpson, Fiona H. Blackhall, Caroline Dive

Publikováno v: Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)

Small cell lung cancer (SCLC) is characterised by prevalent circulating tumour cells (CTCs), early metastasis and poor prognosis. The authors show that SCLC patients have a rare CTC subset with a vasculogenic mimicry (VM) phenotype, and that VM is as

Externí odkaz: https://doaj.org/article/1f6ee31f432d40e09b2cc3b50bd9c622

AFFIRM—A Multiplexed Immunoaffinity Platform That Combines Recombinant Antibody Fragments and LC-SRM Analysis

Autor: Fredrika Carlsson, Anna Säll, Christer Wingren, Niclas Olsson, Sofia Waldemarson, Helena Persson, Mats Ohlin

Publikováno v: Journal of Proteome Research; 13(12), pp 5837-5847 (2014)

Targeted measurements of low abundance proteins in complex mixtures are in high demand in many areas, not the least in clinical applications measuring biomarkers. We here present the novel platform AFFIRM (AFFInity sRM) that utilizes the power of ant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f0471029167e5a961d4fe20afd4ae09
https://doi.org/10.1021/pr500757s

Vasculogenic mimicry in small cell lung cancer

Autor: Christopher P. E. Chester, Hui Sun Leong, Nicole Simms, Peter Kuhn, Lynsey Priest, Fiona H Blackhall, Alberto Fusi, Sumitra Mohan, Benjamin Abbott, Mary J.C. Hendrix, Ged Brady, Richard E.B. Seftor, Radoslaw Polanski, Anders Carlsson, Fredrika Carlsson, Robert Metcalf, Elisabeth A. Seftor, Francesca Trapani, SC Williamson, Caroline Dive, Jenny Antonello, Andrew Hughes, Kathryn Simpson, Daisuke Nonaka, Crispin J. Miller, Dominic G. Rothwell, James W. Hicks

Publikováno v: Williamson, S C, Metcalf, R L, Trapani, F, Mohan, S, Antonello, J, Abbott, B, Leong, H S, Chester, C, Simms, N, Polanski, R, Nonaka, D, Priest, L, Fusi, A, Carlsson, F, Carlsson, A, Hendrix, M J C, Seftor, R E B, Seftor, E A, Rothwell, D G, Hughes, A, Hicks, J, Miller, C, Kuhn, P, Brady, G, Simpson, K L, Blackhall, F H & Dive, C 2016, ' Vasculogenic mimicry in small cell lung cancer ', Nature Communications, vol. 7, pp. 13322 . https://doi.org/10.1038/ncomms13322, https://doi.org/10.1038/ncomms13322
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Trapani, F, Metcalf, R L, Hodgkinson, C L, Polanski, R, Bola, B, Nonaka, D, Fusi, A, Priest, L, Hendrix, M J C, Seftor, R E B, Seftor, E A, Morrow, C J, Antonello, J, Brady, G, Miller, C, Leong, H S, Rothwell, D, Blackhall, F, Williamson, S, Dive, C & Simpson, K L 2015, ' Vasculogenic Mimicry in Small Cell Lung Cancer ', Journal of Thoracic Oncology, vol. 10, no. 9 . https://doi.org/10.1038/ncomms13322

Small cell lung cancer (SCLC) is characterized by prevalent circulating tumour cells (CTCs), early metastasis and poor prognosis. We show that SCLC patients (37/38) have rare CTC subpopulations co-expressing vascular endothelial-cadherin (VE-cadherin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59b365016485bf0cea596e73fed88594
https://doi.org/10.1038/ncomms13322