Zobrazeno 1 - 10
of 371
pro vyhledávání: '"Fredrik Pontén"'
Autor:
Olivia Wegrzyniak, Bo Zhang, Johanna Rokka, Maria Rosestedt, Bogdan Mitran, Pierre Cheung, Emmi Puuvuori, Sofie Ingvast, Jonas Persson, Helena Nordström, John Löfblom, Fredrik Pontén, Fredrik Y. Frejd, Olle Korsgren, Jonas Eriksson, Olof Eriksson
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 8, Iss 1, Pp 1-18 (2023)
Abstract Background Platelet-derived growth factor receptor beta (PDGFRβ) is a receptor overexpressed on activated hepatic stellate cells (aHSCs). Positron emission tomography (PET) imaging of PDGFRβ could potentially allow the quantification of fi
Externí odkaz:
https://doaj.org/article/84daea9b1f234c4eacb9912e8eedc172
Autor:
Fei Wang, Peiwen Ding, Xue Liang, Xiangning Ding, Camilla Blunk Brandt, Evelina Sjöstedt, Jiacheng Zhu, Saga Bolund, Lijing Zhang, Laura P. M. H. de Rooij, Lihua Luo, Yanan Wei, Wandong Zhao, Zhiyuan Lv, János Haskó, Runchu Li, Qiuyu Qin, Yi Jia, Wendi Wu, Yuting Yuan, Mingyi Pu, Haoyu Wang, Aiping Wu, Lin Xie, Ping Liu, Fang Chen, Jacqueline Herold, Joanna Kalucka, Max Karlsson, Xiuqing Zhang, Rikke Bek Helmig, Linn Fagerberg, Cecilia Lindskog, Fredrik Pontén, Mathias Uhlen, Lars Bolund, Niels Jessen, Hui Jiang, Xun Xu, Huanming Yang, Peter Carmeliet, Jan Mulder, Dongsheng Chen, Lin Lin, Yonglun Luo
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Pigs are important large animal models for biomedical research. Here, the authors construct a single-cell landscape of pig tissues, unravelling the phenotypic heterogeneity of blood endothelial cells in adipose tissues and the evolutionally conserved
Externí odkaz:
https://doaj.org/article/c21d50994fe24c6aa783a0e4f2146142
Autor:
David Kotol, Jakob Woessmann, Andreas Hober, María Bueno Álvez, Khue Hua Tran Minh, Fredrik Pontén, Linn Fagerberg, Mathias Uhlén, Fredrik Edfors
Publikováno v:
Cancers, Vol 15, Iss 19, p 4764 (2023)
Mass spectrometry based on data-independent acquisition (DIA) has developed into a powerful quantitative tool with a variety of implications, including precision medicine. Combined with stable isotope recombinant protein standards, this strategy prov
Externí odkaz:
https://doaj.org/article/4e8dfd9c67bb4b4db87257fe1e6b221a
Autor:
Max Karlsson, Evelina Sjöstedt, Per Oksvold, Åsa Sivertsson, Jinrong Huang, María Bueno Álvez, Muhammad Arif, Xiangyu Li, Lin Lin, Jiaying Yu, Tao Ma, Fengping Xu, Peng Han, Hui Jiang, Adil Mardinoglu, Cheng Zhang, Kalle von Feilitzen, Xun Xu, Jian Wang, Huanming Yang, Lars Bolund, Wen Zhong, Linn Fagerberg, Cecilia Lindskog, Fredrik Pontén, Jan Mulder, Yonglun Luo, Mathias Uhlen
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-18 (2022)
Abstract Background There is a need for functional genome-wide annotation of the protein-coding genes to get a deeper understanding of mammalian biology. Here, a new annotation strategy is introduced based on dimensionality reduction and density-base
Externí odkaz:
https://doaj.org/article/1a4c2eb074664d69abac78894b05f1bc
Autor:
Abdellah Tebani, Jelena Jotanovic, Neda Hekmati, Åsa Sivertsson, Olafur Gudjonsson, Britt Edén Engström, Johan Wikström, Mathias Uhlèn, Olivera Casar-Borota, Fredrik Pontén
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-16 (2021)
Abstract Pituitary neuroendocrine tumors (PitNETs) are common, generally benign tumors with complex clinical characteristics related to hormone hypersecretion and/or growing sellar tumor mass. PitNETs can be classified based on the expression pattern
Externí odkaz:
https://doaj.org/article/9310c583b1f143c397522ca78e786048
Autor:
Fei Wang, Peiwen Ding, Xue Liang, Xiangning Ding, Camilla Blunk Brandt, Evelina Sjöstedt, Jiacheng Zhu, Saga Bolund, Lijing Zhang, Laura P. M. H. de Rooij, Lihua Luo, Yanan Wei, Wandong Zhao, Zhiyuan Lv, János Haskó, Runchu Li, Qiuyu Qin, Yi Jia, Wendi Wu, Yuting Yuan, Mingyi Pu, Haoyu Wang, Aiping Wu, Lin Xie, Ping Liu, Fang Chen, Jacqueline Herold, Joanna Kalucka, Max Karlsson, Xiuqing Zhang, Rikke Bek Helmig, Linn Fagerberg, Cecilia Lindskog, Fredrik Pontén, Mathias Uhlen, Lars Bolund, Niels Jessen, Hui Jiang, Xun Xu, Huanming Yang, Peter Carmeliet, Jan Mulder, Dongsheng Chen, Lin Lin, Yonglun Luo
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-2 (2022)
Externí odkaz:
https://doaj.org/article/d4cf4c7a7e6b438db4f2246d1eed4075
Autor:
Sanna Byström, Claudia Fredolini, Per-Henrik Edqvist, Etienne-Nicholas Nyaiesh, Kimi Drobin, Mathias Uhlén, Michael Bergqvist, Fredrik Pontén, Jochen M. Schwenk
Publikováno v:
Translational Oncology, Vol 10, Iss 3, Pp 385-395 (2017)
BACKGROUND: Blood-based proteomic profiling may aid and expand our understanding of diseases and their different phenotypes. The aim of the presented study was to profile serum samples from patients with malignant melanoma using affinity proteomic as
Externí odkaz:
https://doaj.org/article/c1388b73ca554fedb1b3bfd0ebfaf152
Autor:
Ananya Roy, Sylwia Libard, Holger Weishaupt, Ida Gustavsson, Lene Uhrbom, Göran Hesselager, Fredrik J. Swartling, Fredrik Pontén, Irina Alafuzoff, Elena Tchougounova
Publikováno v:
Frontiers in Oncology, Vol 7 (2017)
Metastatic brain tumors continue to be a clinical problem, despite new therapeutic advances in cancer treatment. Brain metastases (BMs) are among the most common mass lesions in the brain that are resistant to chemotherapies, have a very poor prognos
Externí odkaz:
https://doaj.org/article/4921c0771bfc42b88baaa71cac492952
Autor:
Christina Siesing, Halfdan Sorbye, Anca Dragomir, Per Pfeiffer, Camilla Qvortrup, Fredrik Pontén, Karin Jirström, Bengt Glimelius, Jakob Eberhard
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182512 (2017)
High expression of the RNA-binding motif protein 3 (RBM3) has been shown to correlate, with prolonged survival in several malignant diseases and with the benefit of platinum-based chemotherapy in ovarian cancer. The aim of this study was to evaluate
Externí odkaz:
https://doaj.org/article/06c949eda58648e39cb16adef866f642
Autor:
Mathias Uhlén, Björn M Hallström, Cecilia Lindskog, Adil Mardinoglu, Fredrik Pontén, Jens Nielsen
Publikováno v:
Molecular Systems Biology, Vol 12, Iss 4, Pp n/a-n/a (2016)
Abstract Quantifying the differential expression of genes in various human organs, tissues, and cell types is vital to understand human physiology and disease. Recently, several large‐scale transcriptomics studies have analyzed the expression of pr
Externí odkaz:
https://doaj.org/article/c6279c823e8b41ceb63eb9ec06c6dc07