Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Fredrik Melander"'
Autor:
Sophie B. Jensen, Ditte E. Jæhger, Elizabeth Serrano-Chávez, Hólmfríður R. Halldórsdóttir, Trine B. Engel, Jennifer S. Jørgensen, Unnur J. Björgvinsdóttir, Serhii Kostrikov, Marouschka J. Scheeper, Lars Ringgaard, Linda M. Bruun, Camilla Stavnsbjerg, Esben Christensen, Martin Bak, Julianna Thuroczy, Lajos Balogh, Andreas T. I. Jensen, Fredrik Melander, Andreas Kjaer, Jonas R. Henriksen, Anders E. Hansen, Thomas L. Andresen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Cancer curing immune responses against heterogeneous solid cancers require that a coordinated immune activation is initiated in the antigen avid but immunosuppressive tumor microenvironment (TME). The plastic TME, and the poor systemic toler
Externí odkaz:
https://doaj.org/article/d50340662d0947fe879e809163698218
Autor:
Kamilla Norregaard, Jesper T Jørgensen, Marina Simón, Fredrik Melander, Lotte K Kristensen, Pól M Bendix, Thomas L Andresen, Lene B Oddershede, Andreas Kjaer
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177997 (2017)
Within the field of nanoparticle-assisted photothermal cancer therapy, focus has mostly been on developing novel heat-generating nanoparticles with the right optical and dimensional properties. Comparison and evaluation of their performance in tumor-
Externí odkaz:
https://doaj.org/article/abaa70fb7c214c879d5928c61465a523
Autor:
Sophie Jensen, Elizabeth Serrano-Chávez, Hólmfridur Halldórsdóttir, Trine Engel, Jennifer Jørgensen, Serhii Kostrikov, Marouschka Scheeper, Lars Ringgaard, Linda Bruun, Camilla Stavnsbjerg, Ditte Jæhger, Esben Christensen, Martin Bak, Julianna Thuroczy, Lajos Balogh, Andreas Jensen, Fredrik Melander, Andreas Kjaer, Jonas Henriksen, Anders Hansen, Thomas Andresen
Cancer curing immune responses against heterogeneous solid cancers require that a coordinated immune activation is initiated in the antigen avid but immunosuppressive tumor microenvironment (TME). The plastic, immunosuppressive TME, and the poor syst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f7cae691685a4bcd0cd3e8691764c6a
https://doi.org/10.21203/rs.3.rs-2511064/v1
https://doi.org/10.21203/rs.3.rs-2511064/v1
Autor:
Marina Simón, Jesper Tranekjær Jørgensen, Andreas Kjaer, Fredrik Melander, Thomas Lars Andresen, Anders Christensen
Publikováno v:
Cancers
Volume 13
Issue 22
Simón, M, Jørgensen, J T, Melander, F, Andresen, T L, Christensen, A & Kjaer, A 2021, ' Photothermal therapy as adjuvant to surgery in an orthotopic mouse model of human fibrosarcoma ', Cancers, vol. 13, no. 22, 5820 . https://doi.org/10.3390/cancers13225820
Cancers, Vol 13, Iss 5820, p 5820 (2021)
Volume 13
Issue 22
Simón, M, Jørgensen, J T, Melander, F, Andresen, T L, Christensen, A & Kjaer, A 2021, ' Photothermal therapy as adjuvant to surgery in an orthotopic mouse model of human fibrosarcoma ', Cancers, vol. 13, no. 22, 5820 . https://doi.org/10.3390/cancers13225820
Cancers, Vol 13, Iss 5820, p 5820 (2021)
Simple Summary Combining tumor surgery with other types of treatment can be useful when dealing with aggressive tumors or tumors in difficult locations. Photothermal therapy (PTT) is a technique based on the use of light-absorbing nanoparticles that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b992b576d70471a95d1866d2385d727e
Autor:
Matthias, Fach, Frederikke P, Fliedner, Paul J, Kempen, Fredrik, Melander, Anders E, Hansen, Linda M, Bruun, Ulli, Köster, Emanuel, Sporer, Andreas, Kjaer, Thomas L, Andresen, Andreas I, Jensen, Jonas R, Henriksen
Publikováno v:
Advanced healthcare materials. 10(10)
Local application of radioactive sources as brachytherapy is well established in oncology. This treatment is highly invasive however, due to the insertion of millimeter sized metal seeds. The authors report the development of a new concept for brachy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d98ac0189a8b5e4f200caffcc82b5912
https://pubmed.ncbi.nlm.nih.gov/33763995
https://pubmed.ncbi.nlm.nih.gov/33763995
Autor:
Rasmus Irming Jølck, Trine Bjørnbo Engel, Thomas Lars Andresen, Jonas Rosager Henriksen, Fredrik Melander, Per Roos, Paul J. Kempen, Anncatrine Luisa Petersen
Publikováno v:
Nanoscale. 12(43)
The main structural element defining the cell is the lipid membrane, which is an integral part of regulating the fluxes of ion and nutrition molecules in and out of the cell. Surprisingly, copper ions were found to have anomalous membrane permeabilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40d5fb3fb9becc9b84e3706dce6d30cf
https://pubmed.ncbi.nlm.nih.gov/33146209
https://pubmed.ncbi.nlm.nih.gov/33146209
Autor:
Kasper Kristensen, Andreas Kjaer, Jonas Rosager Henriksen, Frederikke P. Fliedner, Fredrik Melander, Rasmus Irming Jølck, Anders Elias Hansen, Dennis Ringkjøbing Elema, Rasmus Eliasen, Thomas Lars Andresen, Lars Ringgaard, Martin Bak, Trine Bjørnbo Engel
Publikováno v:
Science Advances
Ringgaard, L, Melander, F, Eliasen, R, Henriksen, J R, Jølck, R I, Engel, T B, Bak, M, Fliedner, F P, Kristensen, K, Elema, D R, Kjaer, A, Hansen, A E & Andresen, T L 2020, ' Tumor repolarization by an advanced liposomal drug delivery system provides a potent new approach for chemo-immunotherapy ', Science Advances, vol. 6, no. 36, eaba5628 . https://doi.org/10.1126/sciadv.aba5628
Ringgaard, L, Melander, F, Eliasen, R, Henriksen, J R, Jølck, R I, Engel, T B, Bak, M, Fliedner, F P, Kristensen, K, Elema, D R, Kjaer, A, Hansen, A E & Andresen, T L 2020, ' Tumor repolarization by an advanced liposomal drug delivery system provides a potent new approach for chemo-immunotherapy ', Science Advances, vol. 6, no. 36, eaba5628 . https://doi.org/10.1126/sciadv.aba5628
Liposomal oxaliplatin remodels the tumor microenvironment and potentiate TLR-agonist–mediated immune responses in cancer.
Immunosuppressive cells in the tumor microenvironment allow cancer cells to escape immune recognition and support cancer
Immunosuppressive cells in the tumor microenvironment allow cancer cells to escape immune recognition and support cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9075070e972158e969e56067aa9719fd
http://europepmc.org/articles/PMC7473747
http://europepmc.org/articles/PMC7473747
Autor:
Andreas Tue Ingemann Jensen, Andreas Kjaer, Frederikke P. Fliedner, Rasmus Eliasen, Wenbo Wang, Fredrik Melander, Jonas Rosager Henriksen, Anders Elias Hansen, Thomas Lars Andresen
Publikováno v:
Wang, W, Fliedner, F P, Hansen, A E, Eliasen, R, Melander, F, Kjær, A, Andresen, T L, Jensen, A I & Henriksen, J R 2020, ' Preclinical evaluation of cationic DOTA-triarginine-lipid conjugates for theranostic liquid brachytherapy ', Theranostics, vol. 10, no. 3, pp. 142-155 . https://doi.org/10.7150/ntno.44562
Nanotheranostics
Wang, W, Fliedner, F P, Hansen, A E, Eliasen, R, Melander, F, Kjaer, A, Andresen, T L, Jensen, A I & Henriksen, J R 2020, ' Preclinical evaluation of cationic DOTA-triarginine-lipid conjugates for theranostic liquid brachytherapy ', Nanotheranostics, vol. 4, no. 3, pp. 142-155 . https://doi.org/10.7150/ntno.44562
Nanotheranostics
Wang, W, Fliedner, F P, Hansen, A E, Eliasen, R, Melander, F, Kjaer, A, Andresen, T L, Jensen, A I & Henriksen, J R 2020, ' Preclinical evaluation of cationic DOTA-triarginine-lipid conjugates for theranostic liquid brachytherapy ', Nanotheranostics, vol. 4, no. 3, pp. 142-155 . https://doi.org/10.7150/ntno.44562
Liquid brachytherapy is an emerging technology for internal radiation therapy where liquids containing radionuclides are administered directly into solid tumors. These technologies are less invasive than conventional brachytherapy, and can potentiall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::852c7616bdc81a16bd7c2ecac5bb2b24
https://orbit.dtu.dk/en/publications/ea594aed-13d7-4638-bee1-c9c1bc950971
https://orbit.dtu.dk/en/publications/ea594aed-13d7-4638-bee1-c9c1bc950971
Autor:
Arto Heiskanen, Thomas Lars Andresen, Francesca Garbarino, Fredrik Melander, Giorgio Ferrari, Kinga Zor, Claudia Caviglia, Chiara Canali, Marco Sampietro, Roberto Raiteri, Jenny Emnéus
Publikováno v:
Caviglia, C, Garbarino, F, Canali, C, Melander, F, Raiteri, R, Ferrari, G, Sampietro, M, Heiskanen, A, Andresen, T L, Zor, K & Emnéus, J 2020, ' Monitoring cell endocytosis of liposomes by real-time electrical impedance spectroscopy ', Analytical and Bioanalytical Chemistry, vol. 412, no. 24, pp. 6371-6380 . https://doi.org/10.1007/s00216-020-02592-x
Evaluation and understanding the effect of drug delivery in in vitro systems is fundamental in drug discovery. We present an assay based on real-time electrical impedance spectroscopy (EIS) measurements that can be used to follow the internalisation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca702741138acf2aea082269902b503a
http://hdl.handle.net/11567/1034470
http://hdl.handle.net/11567/1034470
Autor:
Andreas Kjaer, Dennis Ringkjøbing Elema, Betina Børresen, Gael Clergeaud, Jonas Rosager Henriksen, Fredrik Melander, Jennifer Solgaard Jørgensen, Thomas Lars Andresen, Anders Elias Hansen, Janos Szebeni, Annemarie T. Kristensen, Svend Aage Engelholm
Publikováno v:
ACS Nano. 12:11386-11398
The enhanced permeability and retention (EPR) effect increases tumor accumulation of liposomal chemotherapy and should, in theory, increase anticancer effects and lower toxicity. Unfortunately, liposomal chemotherapy has generally not met the expecte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::318a09220486860797ecc4a04cb8f90c
https://doi.org/10.1021/acsnano.8b06266
https://doi.org/10.1021/acsnano.8b06266