Výsledky vyhledávání - "Fredrik Jesacher"

3-(4-Aroyl-1-methyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamides as a New Class of Synthetic Histone Deacetylase Inhibitors. 3. Discovery of Novel Lead Compounds through Structure-Based Drug Design and Docking Studies

Autor: Roberto Scatena, Antonello Mai, Gunther Brosch, Sergio Valente, Fredrik Jesacher, Ilaria Cerbara, Patrizia Bottoni, Rino Ragno, Peter Loidl, Silvio Massa

Publikováno v: Journal of Medicinal Chemistry. 47:1351-1359

Aroyl-pyrrole-hydroxy-amides (APHAs) are a new class of synthetic HDAC inhibitors recently described by us. Through three different docking procedures we designed, synthesized, and tested two new isomers of APHA lead compound 3-(4-benzoyl-1-methyl-1H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::145c03e03182cf2e85b49e7ed12df248
https://doi.org/10.1021/jm031036f

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