Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Fredrik J. Olson"'
Publikováno v:
International journal of technology assessment in health care. 33(4)
Objectives: For medical devices, benefits other than direct clinical effects may have a large impact on the patients’ well-being, but a standardized method for measuring these benefits is unavailable. The objective was to explore potential patient
Autor:
Johannes Hulthe, Carina Sihlbom, Björn Fagerberg, Pia Davidsson, Fredrik J. Olson, Göran Bergström
Publikováno v:
Biochemical and Biophysical Research Communications. 401:574-580
Identifying proteins associated with a complicated atherosclerotic plaque phenotype would provide potential biomarkers for detection of patients at elevated risk for clinically overt disease. We hypothesized that the protein content of carotid athero
Autor:
Erik Elias, Carl Johan Behre, Göran Bergström, Hans Herlitz, Fredrik J. Olson, Ville Wallenius
Publikováno v:
Scandinavian Journal of Clinical and Laboratory Investigation. 70:487-491
We have previously described that the sodium/lithium countertransport (SLC) in the erythrocyte cell membrane is closely linked to obesity and insulin resistance. Adiponectin and retinol-binding protein 4 (RBP-4) are believed to affect obesity and ins
Autor:
Björn Fagerberg, Gerhard Brohall, Fredrik J. Olson, Mikael Ryndel, Caroline Schmidt, Göran Bergström, Ulrica Prahl, Carl Johan Behre
Publikováno v:
Clinica Chimica Acta. 411:500-504
Background Haptoglobin polymorphism generates three common human genotypes: Hp1-1, Hp2-1 and Hp2-2. Among subjects with diabetes, Hp2-2 is associated with an elevated risk to develop cardiovascular disease. The impact of haptoglobin genotype on subcl
Autor:
Lars Karlström, Fredrik J. Olson, Björn Fagerberg, Göran Bergström, Josefin Kjelldahl, Mikael Ryndel, Levent M. Akyürek, Lars Rosengren
Publikováno v:
Journal of Vascular Research. 47:221-230
Background: The heterogeneous structure of carotid atherosclerotic plaques may be better understood if it is related to blood flow variations, influencing gene expression and cellular functions. Upstream of the maximum stenosis there is laminar blood
Autor:
Björn Fagerberg, Josefin Kjelldahl, Margareta Jernås, Dag S. Thelle, Daniel Hägg, Fredrik J. Olson, Per-Arne Svensson, Lena M. S. Carlsson
Publikováno v:
Atherosclerosis. 204:e15-e20
OBJECTIVE: Using gene expression profiling, we aimed to identify genes that are predominantly expressed in human carotid atherosclerotic plaques. Such genes may be important in atherogenesis and pathophysiology of the plaque, and genes that encode fo
Autor:
Thomas Link, Rosalind Graham, Thomas Noll, Joyce Taylor-Papadimitriou, Gunnar C. Hansson, Joy Burchell, Gianfranco Picco, Malin Bäckström, Hasse Karlsson, Fredrik J. Olson
Publikováno v:
Biochemical Journal. 376:677-686
We have developed an expression system for the production of large quantities of recombinant MUC1 mucin in CHO-K1 (Chinese-hamster ovary K1) cells. The extracellular part of human MUC1, including 16 MUC1 tandem repeats, was produced as a fusion prote
Autor:
Gunnar C. Hansson, Matthias Mörgelin, Klaus Godl, Hasse Karlsson, Martin E. Lidell, Malin E. V. Johansson, Young S. Kim, James R. Gum, Fredrik J. Olson
Publikováno v:
Journal of Biological Chemistry. 277:47248-47256
The N terminus of the human MUC2 mucin (amino acids 1-1397) has been expressed as a recombinant tagged protein in Chinese hamster ovary cells. The intracellular form was found to be an endoglycosidase H-sensitive monomer, whereas the secreted form wa
Publikováno v:
Glycoconjugate Journal. 19:67-75
The glycosylation alterations of mouse small intestinal mucins during a 12-day infectious cycle caused by the parasite Nippostrongylus brasiliensis have been studied. The guanidinium chloride insoluble mucins were isolated at day 0 to 12 from the sma
Autor:
Lennart Enerbäck, Niclas G. Karlsson, Per-Åke Jovall, Gunnar C. Hansson, Ylva Andersch, Fredrik J. Olson
Publikováno v:
Biochemical Journal. 350:805-814
The sialylation of the oligosaccharides from small-intestinal mucins during a 13-day infectious cycle was studied in Sprague–Dawley rats with the parasite Nippostrongylus brasiliensis. Sialic acid analysis and release, permethylation and analysis b