Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Fredrik Gussing"'
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e46269 (2012)
Regulating transgene expression in vivo by delivering oral drugs has been a long-time goal for the gene therapy field. A novel gene regulating system based on targeted proteasomal degradation has been recently developed. The system is based on a dest
Externí odkaz:
https://doaj.org/article/ede1238e80cc468291c620c3498024d3
Publikováno v:
Neuroscience Letters. 530:29-34
Gene therapy is a promising therapeutic tool for Parkinson's disease (PD), but there is a lack of evaluated cell specific promoters that are relevant for the disease. We have chosen PD relevant promoter candidates for gene therapy vectors based on ei
Publikováno v:
Journal of Neurochemistry. 110:1263-1275
In mouse, sexual, aggressive, and social behaviors are influenced by G protein-coupled vomeronasal receptor signaling in two distinct subsets of vomeronasal sensory neurons (VSNs): apical and basal VSNs. In addition, G protein-signaling by these rece
Publikováno v:
Journal of Neuroscience Research. 76:442-452
In this study we have identified a repertoire of chemosensory receptors expressed in the septal organ (SO). The results suggest that septal organ neurons are specified to express receptor genes belonging to class II olfactory receptors that are also
Publikováno v:
Current Biology. 13:1214-1219
Several social and reproductive behaviors are under the influence of the vomeronasal (VN) organ; VN neurons detect odorous molecules emitted by individuals of the same species. There are two types of VN neurons, and these differ in their expression o
Autor:
Maria Hägglund, Staffan Bohm, Fredrik Gussing, Viktoria Vedin, E.Marianne Norlin, Mattias Alenius
Publikováno v:
Molecular and Cellular Neuroscience. 18:283-295
Signals regulating diversification of olfactory sensory neurons to express odorant receptors and other genes necessary for correct assembly of the olfactory sensory map persist in the olfactory epithelium of adult mouse. We have screened for genes wi
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 515
Lentiviral vectors offer many advantages within the central nervous system. They are capable of transfecting neurons and can be readily manipulated for selective expression. This chapter describes the production and use of lentiviruses to deliver GFP
Autor:
Staffan Bohm, Fredrik Gussing
Publikováno v:
The European journal of neuroscience. 19(9)
The mouse olfactory epithelium (OE) is divided into spatial zones, each containing neurons expressing zone-specific subsets of odorant receptor genes. Likewise, the vomeronasal (VN) organ is organized into apical and basal subpopulations of neurons e
Publikováno v:
Journal of Neuroscience Research; May2004, Vol. 76 Issue 4, p442-452, 11p