Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Fredrik B. Thorén"'
Autor:
Hana Komic, Malin S. Nilsson, Lovisa Wennström, Tagore Sanketh Bandaru, Pekka Jaako, Kristoffer Hellstrand, Fredrik B. Thorén, Anna Martner
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Hydroxyurea (HU) is frequently used in the early phase of chronic myeloid leukemia (CML) to achieve cytoreduction prior to tyrosine kinase inhibitor (TKI) therapy. However, its impact on CML stem and progenitor cells (SPC) remains largely unknown. Th
Externí odkaz:
https://doaj.org/article/f23234d23bb942d0bf1e71632bf7b0e2
Autor:
Malin S. Nilsson, Michael Fiegl, Wolfgang Hiddemann, Wolfgang R. Sperr, Fredrik B. Thorén, Anna Martner, Kristoffer Hellstrand
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Not available.
Externí odkaz:
https://doaj.org/article/3f20d37cbc5e4ebba05a7aa088a86f6a
Autor:
Brwa Ali Hussein, Alexander Hallner, Lovisa Wennström, Mats Brune, Anna Martner, Kristoffer Hellstrand, Elin Bernson, Fredrik B. Thorén
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/0a6225aaf7f04aa6bbdf917a321d10fd
Autor:
Brwa Ali Hussein, Alexander Hallner, Lovisa Wennström, Mats Brune, Anna Martner, Kristoffer Hellstrand, Elin Bernson, Fredrik B. Thorén
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Natural killer cells are important effector cells in the immune response against myeloid malignancies. Previous studies show that the expression of activating NK cell receptors is pivotal for efficient recognition of blasts from patients with acute m
Externí odkaz:
https://doaj.org/article/3ed919fa56004350a6ed3ec2bbec2303
Autor:
Malin S. Nilsson, Alexander Hallner, Mats Brune, Staffan Nilsson, Fredrik B. Thorén, Anna Martner, Kristoffer Hellstrand
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 16, Iss 1, Pp 109-111 (2020)
Immunotherapy with histamine dihydrochloride and low-dose interleukin-2 (HDC/IL-2) reduces the risk of relapse in the post-chemotherapy phase of acute myeloid leukemia (AML). Here we report the results of exploratory analyses of the clinical efficacy
Externí odkaz:
https://doaj.org/article/1115f322ac8e44e4896b7f1c3b9752fc
Autor:
Hanna Grauers Wiktorin, Ebru Aydin, Karin Christenson, Nuttida Issdisai, Fredrik B. Thorén, Kristoffer Hellstrand, Anna Martner
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Interleukin-1 beta (IL-1β), a pro-inflammatory cytokine, has been ascribed a role in the expansion of myeloid progenitors in acute myeloid leukemia (AML) and in promoting myeloid cell-induced suppression of lymphocyte-mediated immunity against malig
Externí odkaz:
https://doaj.org/article/7c0d65116fc642cdbd9af57dfbbac7c2
Autor:
Elin Bernson, Karin Christenson, Silvia Pesce, Malin Pasanen, Emanuela Marcenaro, Simona Sivori, Fredrik B. Thorén
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Neutrophils are potent effector cells and contain a battery of harmful substances and degrading enzymes. A silent neutrophil death, i.e., apoptosis, is therefore of importance to avoid damage to the surrounding tissue and to enable termination of the
Externí odkaz:
https://doaj.org/article/13aa5988cc61480783dec0b3af192754
Autor:
Roberta Kiffin, Hanna Grauers Wiktorin, Malin S. Nilsson, Johan Aurelius, Ebru Aydin, Brianna Lenox, Jonas A. Nilsson, Anders Ståhlberg, Fredrik B. Thorén, Kristoffer Hellstrand, Anna Martner
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
In patients with acute myeloid leukemia (AML), treatment with histamine dihydrochloride (HDC) and low-dose IL-2 (HDC/IL-2) in the post-chemotherapy phase has been shown to reduce the incidence of leukemic relapse. The clinical benefit of HDC/IL-2 is
Externí odkaz:
https://doaj.org/article/758f759ce5a64394afbcaa2d790c2c87
Autor:
Hana Komic, Alexander Hallner, Brwa A. Hussein, Chiara Badami, Anne Wöhr, Kristoffer Hellstrand, Elin Bernson, Fredrik B. Thorén
HLA-B proteins interact with key immune receptors on both T and NK cells, and variants of the encoding gene are associated with outcomes in various pathologies, including autoimmune diseases and malignancies. HLA-B is pivotal in antigen presentation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f49fda21a9062059ae4c4c6dad71e40c
https://doi.org/10.21203/rs.3.rs-2860436/v1
https://doi.org/10.21203/rs.3.rs-2860436/v1
Autor:
Kristoffer Hellstrand, Fredrik B. Thorén, Anna Martner, Johan Aurelius, Olle Werlenius, Ebru Aydin, Roberta Kiffin, Alexander Hallner, Ali A. Akhiani
The phosphatidylinositol-4,5-bisphosphate-3 kinase-δ (PI3Kδ) inhibitor idelalisib, used alone or in combination with anti-CD20, is clinically efficacious in B-cell lymphoma and chronic lymphocytic leukemia (CLL) by promoting apoptosis of malignant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d64c16e9eaf6192071104d27b919a54
https://doi.org/10.1158/2326-6066.c.6550396
https://doi.org/10.1158/2326-6066.c.6550396