Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Fredrik B Thorén"'
Autor:
Per Guldberg, Tina M Green, Henrik J Ditzel, Morten F Gjerstorff, Fredrik B Thorén, Sofie Traynor, Mie K Jakobsen, Hana Komic, Yaseelan Palarasah, Christina B Pedersen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 6 (2024)
Cancer/testis antigens (CTAs) are widely expressed in melanoma and lung cancer, emerging as promising targets for vaccination strategies and T-cell-based therapies in these malignancies. Despite recognizing the essential impact of intratumoral hetero
Externí odkaz:
https://doaj.org/article/7b33650554d84d9abe5f3303d625a0d1
Autor:
Brwa Ali Hussein, Linnea Kristenson, Silvia Pesce, Anne Wöhr, Yarong Tian, Alexander Hallner, Mats Brune, Kristoffer Hellstrand, Ka-Wei Tang, Elin Bernson, Fredrik B Thorén
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 8 (2023)
Background The natural killer (NK) complex (NKC) harbors multiple genes such as KLRC1 (encoding NKG2A) and KLRK1 (encoding NKG2D) that are central to regulation of NK cell function. We aimed at determining to what extent NKC haplotypes impact on NK c
Externí odkaz:
https://doaj.org/article/b6c5fb919102458288b4d23545bab390
Autor:
Ali A Akhiani, Olle Werlenius, Johan Aurelius, Charlotta Movitz, Anna Martner, Kristoffer Hellstrand, Fredrik B Thorén
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89646 (2014)
Reactive oxygen species (ROS) are formed by myeloid cells as a defense strategy against microorganisms. ROS however also trigger poly(ADP-ribose) polymerase 1- (PARP-1) dependent cell death (parthanatos) in adjacent lymphocytes, which has been forwar
Externí odkaz:
https://doaj.org/article/b6254d98dcb94cf3a55d4ecbcdad9a7a
Autor:
Hana Komic, Alexander Hallner, Brwa A. Hussein, Chiara Badami, Anne Wöhr, Kristoffer Hellstrand, Elin Bernson, Fredrik B. Thorén
HLA-B proteins interact with key immune receptors on both T and NK cells, and variants of the encoding gene are associated with outcomes in various pathologies, including autoimmune diseases and malignancies. HLA-B is pivotal in antigen presentation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f49fda21a9062059ae4c4c6dad71e40c
https://doi.org/10.21203/rs.3.rs-2860436/v1
https://doi.org/10.21203/rs.3.rs-2860436/v1
Autor:
Elin Bernson, Karin Christenson, Silvia Pesce, Malin Pasanen, Emanuela Marcenaro, Simona Sivori, Fredrik B. Thorén
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Neutrophils are potent effector cells and contain a battery of harmful substances and degrading enzymes. A silent neutrophil death, i.e., apoptosis, is therefore of importance to avoid damage to the surrounding tissue and to enable termination of the
Externí odkaz:
https://doaj.org/article/13aa5988cc61480783dec0b3af192754
Autor:
Kristoffer Hellstrand, Fredrik B. Thorén, Anna Martner, Johan Aurelius, Olle Werlenius, Ebru Aydin, Roberta Kiffin, Alexander Hallner, Ali A. Akhiani
The phosphatidylinositol-4,5-bisphosphate-3 kinase-δ (PI3Kδ) inhibitor idelalisib, used alone or in combination with anti-CD20, is clinically efficacious in B-cell lymphoma and chronic lymphocytic leukemia (CLL) by promoting apoptosis of malignant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d64c16e9eaf6192071104d27b919a54
https://doi.org/10.1158/2326-6066.c.6550396
https://doi.org/10.1158/2326-6066.c.6550396
Autor:
Kristoffer Hellstrand, Fredrik B. Thorén, Anna Martner, Johan Aurelius, Olle Werlenius, Ebru Aydin, Roberta Kiffin, Alexander Hallner, Ali A. Akhiani
Supplementary Figures and Table
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b35c3cb2189d962dd425e7fd4e3e3c6d
https://doi.org/10.1158/2326-6066.22543753.v1
https://doi.org/10.1158/2326-6066.22543753.v1
Autor:
Fredrik B. Thorén, Kristoffer Hellstrand, Anna Martner, Johan Aurelius, Robin Foà, Mats Brune, Jan-Åke Liljeqvist, Ebru Aydin, Karin Christenson, Malin S. Nilsson, Malin Nicklasson, Frida E. Sander, Alexander Hallner, Elin Bernson
Supplementary figures and table
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f15cfda6d1f833d860fe078a8a34bb93
https://doi.org/10.1158/2326-6066.22539496.v1
https://doi.org/10.1158/2326-6066.22539496.v1
Autor:
Fredrik B. Thorén, Kristoffer Hellstrand, Anna Martner, Johan Aurelius, Robin Foà, Mats Brune, Jan-Åke Liljeqvist, Ebru Aydin, Karin Christenson, Malin S. Nilsson, Malin Nicklasson, Frida E. Sander, Alexander Hallner, Elin Bernson
Human cytomegalovirus (CMV) infection is reported to promote NK cell differentiation and education. The CMV-induced generation of highly differentiated adaptive-like NK cells has been proposed to affect favorably on the maintenance of remission in pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::173089a3c05415e3feabaa78851b7cfd
https://doi.org/10.1158/2326-6066.c.6549106.v1
https://doi.org/10.1158/2326-6066.c.6549106.v1
Publikováno v:
Radiation Protection Dosimetry
In contrast to optical colonoscopy, computed tomography colonography (CTC) has the ability to reveal pathology outside of the colon. While identification of colorectal lesions at CTC requires only limited radiation dose, the detection of abnormalitie