Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Fredrik, Ek"'
Autor:
Umut Aydemir, Abdelrazek H. Mousa, Cedric Dicko, Xenofon Strakosas, Muhammad Anwar Shameem, Karin Hellman, Amit Singh Yadav, Peter Ekström, Damien Hughes, Fredrik Ek, Magnus Berggren, Anders Arner, Martin Hjort, Roger Olsson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Without intervention, cardiac arrhythmias pose a risk of fatality. However, timely intervention can be challenging in environments where transporting a large, heavy defibrillator is impractical, or emergency surgery to implant cardiac stimul
Externí odkaz:
https://doaj.org/article/075fd4a8c4a94ceea4111c5175505fec
Autor:
Geriolda Topi, Shakti Ranjan Satapathy, Souvik Ghatak, Karin Hellman, Fredrik Ek, Roger Olsson, Roy Ehrnström, Marie-Louise Lydrup, Anita Sjölander
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-5 (2024)
Externí odkaz:
https://doaj.org/article/5df1f30bb958432f8f975e172fc6bdd9
Autor:
Geriolda Topi, Shakti Ranjan Satapathy, Souvik Ghatak, Karin Hellman, Fredrik Ek, Roger Olsson, Roy Ehrnström, Marie-Louise Lydrup, Anita Sjölander
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract In normal colon tissue, oestrogen receptor alpha (ERα) is expressed at low levels, while oestrogen receptor beta (ERβ) is considered the dominant subtype. However, in colon carcinomas, the ERα/β ratio is often increased, an observation t
Externí odkaz:
https://doaj.org/article/9909d49bdbe2475eb75229dbd8eb2454
Autor:
Martin Hjort, Abdelrazek H. Mousa, David Bliman, Muhammad Anwar Shameem, Karin Hellman, Amit Singh Yadav, Peter Ekström, Fredrik Ek, Roger Olsson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Bioelectronics can potentially complement classical therapies in nonchronic treatments, such as immunotherapy and cancer. In addition to functionality, minimally invasive implantation methods and bioresorbable materials are central to nonchr
Externí odkaz:
https://doaj.org/article/3de6f1aaa3764e0aa605c8cd94c4bfb4
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-17 (2022)
Abstract Glioblastoma (GBM) is the most common and most aggressive primary brain tumor in adults. Glioma stem like cells (GSC) represent the highest cellular hierarchy in GBM and have a determining role in tumor growth, recurrence and patient prognos
Externí odkaz:
https://doaj.org/article/9fd57575b391431ea243f0e6acf21815
Autor:
Svetlana Soboleva, Ryo Kurita, Fredrik Ek, Hugo Åkerstrand, Rita Silvério-Alves, Roger Olsson, Yukio Nakamura, Kenichi Miharada
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
In an imaging-based screen of >3,300 compounds compounds, Soboleva et al identify HDAC inhibitors as mediators of erythroid cell enucleation. They further show that the erythroid-specific cell membrane protein, SPTA1, is downregulated in HDAC inhibit
Externí odkaz:
https://doaj.org/article/61f572de14eb48a18df29210fe97c443
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Publikováno v:
Bio-Protocol, Vol 12, Iss 6 (2022)
Ex vivo culture of primary acute myeloid leukemia (AML) cells is notoriously difficult due to spontaneous differentiation and cell death, which hinders mechanistic and translational studies. To overcome this bottleneck, we have implemented a co-cultu
Externí odkaz:
https://doaj.org/article/dd8359556e17452f85cdd524ad16a772
Autor:
Xenofon Strakosas, Hanne Biesmans, Tobias Abrahamsson, Karin Hellman, Malin Silverå Ejneby, Mary J. Donahue, Peter Ekström, Fredrik Ek, Marios Savvakis, Martin Hjort, David Bliman, Mathieu Linares, Caroline Lindholm, Eleni Stavrinidou, Jennifer Y. Gerasimov, Daniel T. Simon, Roger Olsson, Magnus Berggren
Publikováno v:
Science. 379:795-802
Interfacing electronics with neural tissue is crucial for understanding complex biological functions, but conventional bioelectronics consist of rigid electrodes fundamentally incompatible with living systems. The difference between static solid-stat
Autor:
Simon Hultmark, Aurélie Baudet, Ludwig Schmiderer, Pavan Prabhala, Sara Palma-Tortosa, Carl Sandén, Thoas Fioretos, Rajkumar Sasidharan, Christer Larsson, Sören Lehmann, Gunnar Juliusson, Fredrik Ek, Mattias Magnusson
Publikováno v:
Haematologica, Vol 106, Iss 10 (2020)
Combination treatment has proven effective for patients with acute promyelocytic leukemia, exemplifying the importance of therapy targeting multiple components of oncogenic regulation for a successful outcome. However, recent studies have shown that
Externí odkaz:
https://doaj.org/article/eb07afe4d0a343629492a6a4e40ce48b