Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Fredrick L Eyase"'
Autor:
Fredrick L Eyase, Hoseah M Akala, Luiser Ingasia, Agnes Cheruiyot, Angela Omondi, Charles Okudo, Dennis Juma, Redemptah Yeda, Ben Andagalu, Elizabeth Wanja, Edwin Kamau, David Schnabel, Wallace Bulimo, Norman C Waters, Douglas S Walsh, Jacob D Johnson
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64299 (2013)
Single Nucleotide Polymorphisms (SNPs) in the Pfmdr1, and Pfcrt, genes of Plasmodium falciparum may confer resistance to a number of anti-malaria drugs. Pfmdr1 86Y and haplotypes at Pfcrt 72-76 have been linked to chloroquine (CQ) as well as amodiaqu
Externí odkaz:
https://doaj.org/article/ecedf9a8fc864471a385b8940c1adfdb
Autor:
Wallace D. Bulimo, Mabel Imbuga, Benjamin Opot, Fredrick L. Eyase, Jacob D. Johnson, Luicer A. Ingasia, Edwin Kamau, Hoseah M. Akala
Publikováno v:
Antimicrobial Agents and Chemotherapy. 59:1818-1821
The prevalence of a genetic polymorphism(s) at codon 268 in the cytochrome b gene, which is associated with failure of atovaquone-proguanil treatment, was analyzed in 227 Plasmodium falciparum parasites from western Kenya. The prevalence of the wild-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c34e8757aec4ecafb05eb8239573c8c
https://doi.org/10.1128/aac.03956-14
https://doi.org/10.1128/aac.03956-14
Autor:
Abiy Yenesew, Hannington Twinomuhwezi, Jacques M. Kabaru, Hoseah M. Akala, Bernard T. Kiremire, Matthias Heydenreich, Martin G. Peter, Fredrick L. Eyase, Norman C. Waters, Douglas S. Walsh
Publikováno v:
Bulletin of the Chemical Society of Ethiopia, Vol 23, Iss 3, Pp 409-414 (2009)
From the dichloromethane-methanol (1:1) extract of the seed pods of Derris trifoliata, a new flavanone derivative (S)-lupinifolin 4´-methyl ether was isolated. In addition, the known flavonoids lupinifolin and rotenone were identified. The structure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::6454b072b049859d25a7e47ae2af92bf
http://www.ajol.info/index.php/bcse/article/view/47665
http://www.ajol.info/index.php/bcse/article/view/47665
Autor:
Jelagat, Cheruiyot, Luicer A, Ingasia, Angela A, Omondi, Dennis W, Juma, Benjamin H, Opot, Joseph M, Ndegwa, Joan, Mativo, Agnes C, Cheruiyot, Redemptah, Yeda, Charles, Okudo, Peninah, Muiruri, Ngalah S, Bidii, Lorna J, Chebon, Paul O, Angienda, Fredrick L, Eyase, Jacob D, Johnson, Wallace D, Bulimo, Ben, Andagalu, Hoseah M, Akala, Edwin, Kamau
Publikováno v:
Antimicrobial agents and chemotherapy. 58(7)
In combination with antibiotics, quinine is recommended as the second-line treatment for uncomplicated malaria, an alternative first-line treatment for severe malaria, and for treatment of malaria in the first trimester of pregnancy. Quinine has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::78684d8d9159e49cb5af5801ac49427d
https://pubmed.ncbi.nlm.nih.gov/24752268
https://pubmed.ncbi.nlm.nih.gov/24752268
Ferroquine (FQ), a chloroquine (CQ) analog, is being developed to treat persons with Plasmodium falciparum malaria. In 146 P. falciparum field isolates from western Kenya, we measured 50% inhibitory concentrations (IC50; nM) of CQ and FQ by a SYBR Gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5b8236df121263a7a56e91bdf0f8566
https://europepmc.org/articles/PMC3225175/
https://europepmc.org/articles/PMC3225175/
Autor:
Edgar K Omondi, Godfrey Allan Otieno, Willis Akhwale, Charles O Obonyo, Raymond Omollo, John M. Ong’echa, Kevin Omondi Onyango, Elizabeth Juma, Lucas Otieno, Bernhards Ogutu, Nelly Koskei, Jacob D. Johnson, Douglas J Perkins, Fredrick L. Eyase
Publikováno v:
Malaria Journal
Background This open-label, randomized study evaluated efficacy and safety of artemether-lumefantrine (AL) and dihydroartemisinin-piperaquine (DP) in treatment of uncomplicated falciparum malaria in children below five years of age, to build evidence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77d0bb9bca01e06bac9abe2134575a03