Next-Generation Sequencing (NGS) Methods Show Superior or Equivalent Performance to Non-NGS Methods on BRAF, EGFR, and KRAS Proficiency Testing Samples

Autor: Patricia Vasalos, Annette S. Kim, Jason D. Merker, Lea F. Surrey, Fredrick D. Oakley, Thomas A. Long, Joel T. Moncur

Publikováno v: Archives of Pathology & Laboratory Medicine. 143:980-984

Context.— There has been a rapid expansion of next-generation sequencing (NGS)–based assays for the detection of somatic variants in solid tumors. However, limited data are available regarding the comparative performance of NGS and non-NGS assays

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4bd92fb97276e3e810f7605dd495d0b6
https://doi.org/10.5858/arpa.2018-0394-cp

Next-Generation Sequencing (NGS) Methods Show Superior or Equivalent Performance to Non-NGS Methods on

Autor: Lea F, Surrey, Fredrick D, Oakley, Jason D, Merker, Thomas A, Long, Patricia, Vasalos, Joel T, Moncur, Annette S, Kim

Publikováno v: Archives of pathologylaboratory medicine. 143(8)

There has been a rapid expansion of next-generation sequencing (NGS)-based assays for the detection of somatic variants in solid tumors. However, limited data are available regarding the comparative performance of NGS and non-NGS assays using standar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::33a6cdc432e58c3664721dffc69da724
https://pubmed.ncbi.nlm.nih.gov/30865489

31. The PT alphabet soup: LDT, FDA, NGS, non-NGS, @#$!%

Autor: Alex J. Rai, Nathan D. Montgomery, Julia A. Bridge, Rakesh Nagarajan, Alexander J. Lazar, Lea F. Surrey, Annette S. Kim, Lawrence J. Jennings, Neal I. Lindeman, A. John Iafrate, Stephen B. Montgomery, Alissa Keegan, David L. Rimm, Jason D. Merker, Thomas A. Long, Suzanne Kamel-Reid, Fredrick D. Oakley, Patricia Vasalos, Angela N. Bartley, Paul G. Rothberg, Joel T. Moncur, Bryce P. Portier, Rena Xian, Craig Smail, Kelly A. Devereaux

Publikováno v: Cancer Genetics. :S13

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c79b533b6055a02bd3c6154719075137
https://doi.org/10.1016/j.cancergen.2019.04.037

Lipid Rafts and Caveolin-1 Coordinate Interleukin-1β (IL-1β)-dependent Activation of NFκB by Controlling Endocytosis of Nox2 and IL-1β Receptor 1 from the Plasma Membrane*

Autor: John F. Engelhardt, Fredrick D. Oakley, Rachel L. Smith

Recent evidence suggests that signaling by the proinflammatory cytokine interleukin-1beta (IL-1beta) is dependent on reactive oxygen species derived from NADPH oxidase. Redox signaling in response to IL-1beta is known to require endocytosis of its co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e11153e40db91bf277b735c8e4b21aba
https://europepmc.org/articles/PMC2785168/

JunD protects the liver from ischemia/reperfusion injury by dampening AP-1 transcriptional activation

Autor: Jonathan B Weitzman, Meihui Luo, Jennifer J. Marden, Paul B. McCray, Weihong Zhou, Hongpeng Jia, Fredrick D. Oakley, Moshe Yaniv, John F. Engelhardt, Yulong Zhang

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2008, 283 (11), pp.6687-6695. ⟨10.1074/jbc.M705606200⟩

The AP-1 transcription factor modulates a wide range of cellular processes, including cellular proliferation, programmed cell death, and survival. JunD is a major component of the AP-1 complex following liver ischemia/reperfusion (I/R) injury; howeve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03a31bbd35cc50820120acc45ff33768
https://pubmed.ncbi.nlm.nih.gov/18182393