Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Fredrick, Monsma"'
Autor:
Douglas C. Beshore, Stephen Day, Jason Cassaday, Michelle F. Homsher, Brian Squadroni, David Pechter, Michelle Smith, Lei Ma, Jeffrey D. Hermes, Elizabeth Mohammed, Michelle Hartnett, Paul Zuck, Michael F.A. Finley, Victor N. Uebele, Fredrick Monsma
Publikováno v:
SLAS Discovery. 22:1060-1066
Agonist shift assays feature cross-titrations of allosteric modulators and orthosteric ligands. Information generated in agonist shift assays can include a modulator's effect on the orthosteric agonist's potency (alpha) and efficacy (beta), as well a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4aa4a57a20f8bcde2680cb5a7bfd7c52
https://doi.org/10.1177/2472555217705373
https://doi.org/10.1177/2472555217705373
Autor:
Michelle F, Homsher, Douglas C, Beshore, Jason, Cassaday, Brian, Squadroni, Elizabeth, Mohammed, Michelle, Hartnett, Stephen, Day, Lei, Ma, David, Pechter, Michelle D, Smith, Fredrick, Monsma, Paul, Zuck, Michael F, Finley, Victor N, Uebele, Jeffrey D, Hermes
Publikováno v:
SLAS discovery : advancing life sciences RD. 22(8)
Agonist shift assays feature cross-titrations of allosteric modulators and orthosteric ligands. Information generated in agonist shift assays can include a modulator's effect on the orthosteric agonist's potency (alpha) and efficacy (beta), as well a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d7c79a7b5f4df8eb76db0b4627102a9f
https://pubmed.ncbi.nlm.nih.gov/28426939
https://pubmed.ncbi.nlm.nih.gov/28426939
Autor:
Elizabeth Smith, Arshad Siddiqui, Paul Kirschmeier, Jay Tagat, Fredrick Monsma, Yushi Xiao, Ming Liu, Seema Tevar, David B. Belanger, Doll Ronald J, Sara Esposite, Suining Lee, Tao Yu, Dan Hicklin, Samad Ponery, Andrea D. Basso, Kimberly Gray, Yonglain Zhang
Publikováno v:
Cancer Research. 70:1648-1648
Aurora kinases are required for orderly progression of cells through mitosis. Inhibition of these kinases by siRNA or a small molecule inhibitors results in aberrant endoreduplication and cell death. SCH 1473759 is a novel Aurora inhibitor with poten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::088363723344b576ea6e37524c8707cb
https://doi.org/10.1158/1538-7445.am10-1648
https://doi.org/10.1158/1538-7445.am10-1648